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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Biomedical Research

Browse the latest research summaries in the field of biomedical for spinal cord injury patients and caregivers.

Showing 321-330 of 904 results

Assistive TechnologyBiomedicalTelehealth & Digital Health

A Wireless Magnetoresistive Sensing System for an Intraoral Tongue-Computer Interface

IEEE Trans Biomed Circuits Syst, 2012 • December 1, 2012

The intraoral Tongue Drive System (iTDS) is a tongue-operated, minimally invasive, unobtrusive, and wireless assistive technology that infers users’ intentions by detecting their voluntary tongue moti...

KEY FINDING: The iTDS system-on-a-chip (SoC) features a configurable analog front-end (AFE) that reads the magnetic field variations inside the mouth from four 3-axial magnetoresistive sensors.

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UrologyBiomedical

Safety and Efficacy of a Patient-Controlled Bladder Management System for Treating Urinary Retention in Men

Neurourol Urodyn, 2016 • June 1, 2016

This study evaluated the CymActive Bladder Management System (BMS), an intraurethral catheter with a patient-controlled magnetic valve, in men with urinary retention. The primary endpoint assessed suc...

KEY FINDING: Nine of 23 patients met all four criteria for the primary endpoint (successful placement, low post-void residual volume, no device-related adverse events requiring early removal, and successful removal).

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Spinal Cord InjuryRehabilitationBiomedical

Facilitatory effects of anti-spastic medication on robotic locomotor training in people with chronic incomplete spinal cord injury

Journal of NeuroEngineering and Rehabilitation, 2015 • February 19, 2015

The study investigated whether the anti-spasticity medication Tizanidine could enhance the effects of robotic locomotor treadmill training (LTT) on gait function in individuals with chronic incomplete...

KEY FINDING: Both LTT and TizLTT resulted in significant improvements in walking speed and dorsiflexion maximum strength, with no significant differences between them, using group-averaging analysis.

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Spinal Cord InjuryBioinformaticsBiomedical

An Active Learning Algorithm for Control of Epidural Electrostimulation

IEEE Trans Biomed Eng, 2015 • October 1, 2015

This paper introduces a novel algorithm which can automatically optimize multi-electrode array stimulation parameters. The methodology is based on a novel Gaussian Process Batch Upper Confidence Bound...

KEY FINDING: GP-BUCB successfully controlled spinal electrostimulation in 37 testing sessions, selecting 670 stimuli.

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Assistive TechnologyBiomedical

System Characterization of MAHI EXO-II: A Robotic Exoskeleton for Upper Extremity Rehabilitation

Proc ASME Dyn Syst Control Conf, 2014 • October 1, 2014

This paper presents the performance characterization of the MAHI Exo-II, an upper extremity exoskeleton for stroke and spinal cord injury (SCI) rehabilitation, as a means to validate its clinical impl...

KEY FINDING: The MAHI Exo-II exhibits favorable static friction characteristics, both in magnitude and as a percentage of maximum continuous torque output.

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Assistive TechnologyBiomedical

A Body Machine Interface based on Inertial Sensors

Conf Proc IEEE Eng Med Biol Soc, 2014 • January 1, 2014

This study presents a body machine interface (BMI) utilizing inertial sensors to enable individuals with spinal cord injuries (SCI) to control assistive devices through residual upper-body movements. ...

KEY FINDING: SCI survivors can effectively operate assistive devices through functional reorganization of their residual upper-body movement skills.

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Spinal Cord InjuryAssistive TechnologyBiomedical

Upper Body-Based Power Wheelchair Control Interface for Individuals with Tetraplegia

IEEE Trans Neural Syst Rehabil Eng, 2016 • February 1, 2016

The study developed a body-machine interface (BMI) that uses shoulder kinematics to control a power wheelchair for individuals with tetraplegia. Three individuals with cervical spinal cord injuries we...

KEY FINDING: Participants with spinal cord injuries were able to use small shoulder movements to safely and accurately control a power wheelchair using the BMI.

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Spinal Cord InjuryNeurologyBiomedical

Biomaterial bridges enable regeneration and re-entry of corticospinal tract axons into the caudal spinal cord after SCI: association with recovery of forelimb function

Biomaterials, 2015 • October 1, 2015

This study describes a biodegradable implant using poly(lactideco-glycolide) (PLG) bridges as a carrier scaffold to support regeneration after injury. Taken together, these data suggest that axons ori...

KEY FINDING: Robust co-localization between GFP and neurofilament-200 (NF-200) as well as GFP and GAP-43 was observed at both the rostral and caudal bridge/tissue interface.

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NeurologyRehabilitationBiomedical

Assessment of brain-machine interfaces from the perspective of people with paralysis

J Neural Eng, 2015 • August 1, 2015

This study assessed the attitudes of people with paralysis toward using various BMI technologies to achieve particular benefits, considering the burdens associated with each system. The survey results...

KEY FINDING: Participants were most likely to adopt BMI technology to restore some of their natural upper extremity function, including restoration of hand grasp and/or some degree of natural arm movement.

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NeurologyBiomedicalBiomechanics

An Optimized Proportional-Derivative Controller for the Human Upper Extremity with Gravity

J Biomech, 2015 • October 15, 2015

This study optimized proportional-derivative (PD) controller gain sets on a 3-dimensional biomechanical arm model for goal-oriented reaching movements. The optimized controllers demonstrated significa...

KEY FINDING: Optimization of PD controllers can lead to significant improvements in accuracy for upper extremity movements in a 3D biomechanical arm model.

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