Browse the latest research summaries in the field of biomechanics for spinal cord injury patients and caregivers.
Showing 201-209 of 209 results
BMC Musculoskeletal Disorders, 2024 • August 19, 2024
The study aimed to assess biomechanical changes resulting from OLIF combined with six different internal fixation methods for degenerative spondylolisthesis in the lumbar spine using finite element an...
KEY FINDING: The S-A model had the highest average ROM of six motion modes, followed by LSR, UPS, UCBT, BPS and BCBT.
Bioengineering, 2025 • February 20, 2025
This study compared lumbopelvic kinematics in individuals with and without low back pain (LBP) before and after fatigue. Repetitive lifting induced fatigue, significantly affecting lumbopelvic kinemat...
KEY FINDING: Fatigue significantly altered lumbopelvic kinematics, specifically anterior/posterior translation and rotation around the z-axis, in both groups.
Neural Regeneration Research, 2015 • November 1, 2015
This study aimed to determine the strength characteristics of spinal nerve roots and rami radiculares to better understand the pathogenesis of cauda equina syndrome. Monoaxial tensile tests were perfo...
KEY FINDING: The tensile strength of the nerve root was not rate dependent, remaining relatively constant around 0.7 MPa across different strain rates.
BMC Neuroscience, 2016 • December 6, 2016
The study aimed to assess the usability of the CatWalk XT system to detect early gait abnormalities in a rat model of multiple sclerosis (MOG-EAE) and its applicability in treatment studies. The resul...
KEY FINDING: No preclinical gait abnormalities were detected by the CatWalk system in MOG-EAE rats.
Nature Communications, 2017 • March 20, 2017
This study measured the mechanical properties of the adult rat brain cortex and spinal cord in normal conditions and in response to two different types of traumatic injury using AFM. Healthy CNS tissu...
KEY FINDING: In contrast to scars in other mammalian tissues, CNS tissue significantly softens after injury.
JOURNAL OF NEUROTRAUMA, 2020 • February 1, 2020
This study provides quantitative evidence of chronic mechanical stiffening after SCI using atomic force microscopy microindentation. The study assessed the sensitivity of both mouse and human astrocyt...
KEY FINDING: Chronically injured mouse spinal cord is stiffer than healthy tissue.
Biology Open, 2019 • December 2, 2019
This paper presents an algorithm that automatically characterizes the level of damage to the spinal cord of a Xenopus laevis froglet by analyzing swimming videos. The algorithm measures the position o...
KEY FINDING: The system effectively characterizes spinal cord damage with 97% accuracy by tracking limb movements and extracting kinematic features.
Biophysical Journal, 2020 • January 21, 2020
This study investigates the mechanical properties of the adult zebrafish spinal cord during regeneration after complete spinal cord transection using atomic force microscopy. The researchers mapped the...
KEY FINDING: In uninjured zebrafish, gray matter regions of the spinal cord are stiffer than white matter regions.
Biophysical Journal, 2020 • January 21, 2020
This article discusses a study on zebrafish spinal cord injury and repair, focusing on the biochemomechanical microenvironment changes following transection. The key finding is that spinal cord tissue...
KEY FINDING: Gray matter in the spinal cord is approximately twice as stiff as white matter in both healthy and injured states.