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  4. Can a relatively large spinal cord for the dural sac influence severity of paralysis in elderly patients with cervical spinal cord injury caused by minor trauma?

Can a relatively large spinal cord for the dural sac influence severity of paralysis in elderly patients with cervical spinal cord injury caused by minor trauma?

Medicine, 2020 · DOI: http://dx.doi.org/10.1097/MD.00000000020929 · Published: June 26, 2020

Spinal Cord InjuryAgingMedical Imaging

Simple Explanation

This study investigates whether the size of the spinal cord relative to the dural sac (the membrane surrounding the spinal cord) affects the severity of paralysis in elderly patients who experienced cervical spinal cord injury from minor trauma, such as falls. The researchers measured the spinal cord and dural sac sizes using MRI and CT scans and correlated these measurements with the severity of paralysis as assessed by the Japanese Orthopaedic Association (JOA) scoring system. The study found that a relatively large spinal cord compared to the dural sac at the C5 vertebral level was associated with more severe paralysis in elderly patients with spinal cord injuries caused by minor trauma.

Study Duration
2009 to 2017
Participants
50 elderly patients (aged 65 years or older) with SCI caused by falls on flat ground
Evidence Level
Retrospective review, Observational Study

Key Findings

  • 1
    A significant negative correlation was observed between the JOA score (indicating severity of paralysis) and the spinal cord/dural sac ratio at the mid-C5 vertebral level.
  • 2
    No clear relationship was found between the JOA score and the bony canal anteroposterior diameter (APD) or the spinal cord compression ratio.
  • 3
    Multiple regression analysis confirmed a significant negative correlation between the JOA score and the spinal cord/dural sac ratio at mid-C5.

Research Summary

This study aimed to determine if a relatively large spinal cord for the dural sac influences the severity of paralysis in elderly patients with cervical spinal cord injury (SCI) caused by minor trauma. The study found a significant negative correlation between the severity of paralysis, as measured by the JOA score, and the spinal cord/dural sac ratio at the mid-C5 vertebral level. The findings suggest that elderly individuals with a relatively large spinal cord compared to the size of their dural sac may be more susceptible to severe paralysis following minor cervical trauma.

Practical Implications

Fall Prevention Measures

Implement fall prevention measures in asymptomatic elderly cases if screening shows that the spinal cord/dural sac ratio is high.

Predicting SCI Risk

Spinal cord/dural sac ratio of 80% or higher can reliably identify patients at risk of acute SCI after minor trauma.

Treatment Strategies

The result can be useful for the treatment and prevention of SCI in the elderly.

Study Limitations

  • 1
    Single-center study
  • 2
    Retrospective design
  • 3
    Small number of subjects from a single ethnic group

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