Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 4,111-4,120 of 12,052 results
J. Clin. Med., 2022 • August 30, 2022
The study aimed to evaluate hand motor fatigability in people with SCI, comparing it with able-bodied individuals and analyzing differences between tetraplegia and paraplegia. The findings suggest tha...
KEY FINDING: Muscle force decline during a fatiguing task is similar in SCI participants and controls, suggesting preserved capability to maintain prolonged effort in SCI.
J. Clin. Med., 2022 • August 30, 2022
This case report details the use of a single percutaneous spinal cord epidural stimulation (scES) lead to restore trunk control and standing in a 25-year-old male with T3 complete paraplegia. After on...
KEY FINDING: Reprogramming a single spinal cord stimulation lead resulted in immediate restoration of trunk control during a seated position, even with upper extremity perturbation.
Neural Plasticity, 2022 • August 29, 2022
This review explores the relationship between TSPO and chronic pain, highlighting its vital role in alleviating the initiation and maintenance of various types of chronic pain. TSPO acts as a negative...
KEY FINDING: TSPO is upregulated with microglial activation during neuroinflammation, serving as a marker and predictor of chronic pain.
Cells, 2022 • August 29, 2022
This review highlights the significant role of inflammation in the pathophysiology of SCI and the urgent need for effective treatments. The authors discuss various therapeutic strategies to regulate t...
KEY FINDING: Inflammation following SCI is a complex process with both beneficial and detrimental effects, requiring careful modulation for effective treatment.
Contrast Media & Molecular Imaging, 2022 • August 29, 2022
This research aimed to evaluate the effects of comprehensive nursing under the Omaha system on patients with traumatic paraplegia (TP) and to observe the changes in their magnetic resonance imaging (M...
KEY FINDING: Patients receiving comprehensive nursing under the Omaha system showed significantly higher scores in quality of life, role change, mental health, care, oral hygiene, skin integrity, neuromusculoskeletal (NMS) system function, defecation and urination function, and contagion/infection control compared to those receiving routine nursing.
Frontiers in Cellular Neuroscience, 2022 • August 29, 2022
This study investigates the therapeutic effects of human umbilical cord mesenchymal stem cell-derived small extracellular vesicles (hucMSC-sEVs) on spinal cord injury (SCI) in a rat model. The finding...
KEY FINDING: hucMSC-sEVs dramatically promoted the recovery of spinal cord function in a rat model of SCI, as evidenced by improved BBB scores.
International Journal of Biological Sciences, 2022 • August 29, 2022
This study demonstrates the therapeutic potential of VitD after TSCI by improving the integrity of myelin sheath through c-Myc suppression. Although the mechanisms of injury and pathophysiological alt...
KEY FINDING: VitD treatment post-TSCI effectively improved hindlimb movement in rats with normal VitD level irrespective of injury severity.
Tissue Eng Regen Med, 2022 • August 29, 2022
This study investigated the efficacy and safety of transplanting human polysialylated-neural cell adhesion molecule (PSA-NCAM)-positive neural precursor cells (hNPCsPSA-NCAM?) into rats with spinal co...
KEY FINDING: Transplantation of hNPCsPSA-NCAM? into injured spinal cords of rats significantly improved locomotor function.
Journal of Cardiothoracic Surgery, 2022 • August 26, 2022
This paper presents a case of hemothorax in a 13-year-old girl caused by a costal exostosis injuring her diaphragm. The authors reviewed similar cases in the literature and found that injury to the di...
KEY FINDING: Injury to the diaphragm is the primary cause of hemothorax caused by costal osteochondroma.
Medicine, 2022 • August 26, 2022
This retrospective study compared MRI features of SCI and CCM patients with intramedullary high-intensity lesions. The study measured lesion length, assessed snake-eye appearance, and calculated contr...
KEY FINDING: The longitudinal length of T2 high-intensity lesions was significantly longer in SCI patients than in CCM patients.