Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 3,941-3,950 of 12,052 results
Spine Surg Relat Res, 2022 • October 1, 2022
This systematic review and meta-analysis aimed to evaluate the efficacy of mesenchymal stem cell-derived conditioned media (MSC-CM) in promoting motor recovery following spinal cord injury (SCI) in an...
KEY FINDING: MSC-CM administration in SCI animal models promotes motor recovery, indicating a potential therapeutic effect. MSC-CM administration in SCI animal models promotes motor recovery
Journals of Gerontology: Biological Sciences, 2022 • October 1, 2022
This study characterized the effects of laparotomy on postoperative physical function and skeletal muscle gene expression in male C57BL/6N mice across life span. The study found that laparotomy-induce...
KEY FINDING: Laparotomy induced an age-associated postoperative decline in forelimb grip strength, with the greatest decline in the oldest mice.
Neural Regen Res, 2022 • October 1, 2022
This review defines respiratory plasticity post-spinal cord injury, discusses research models, and explores translation to clinical research. The review highlights neural interfacing, activity-based t...
KEY FINDING: Spinal interneurons (SpINs) are key therapeutic targets for promoting functional recovery post-SCI due to their role in modulating respiratory output.
Neural Regeneration Research, 2022 • October 1, 2022
PNI triggers a series of pathophysiological changes at the level of the cell body, at the site of injury, and in the target organ, reflecting the overall structure of the nervous system. Electrical st...
KEY FINDING: PNI leads to physiological and pathological changes in the spinal cord, injury site, and target organs, causing dysfunction.
Journal of Neurotrauma, 2022 • October 1, 2022
This multi-center study examined white matter changes after mTBI using DTI, finding widespread higher levels of AD, MD, and RD, and lower levels of FA, at two weeks after trauma compared with matched ...
KEY FINDING: Patients with mTBI showed higher levels of axial diffusivity (AD), mean diffusivity (MD), and radial diffusivity (RD) in white matter compared to controls at both two weeks and six months post-injury.
European Journal of Physical and Rehabilitation Medicine, 2022 • October 1, 2022
The study aimed to evaluate the performance of a prediction model, previously validated for traumatic SCI, in predicting bowel management independence one year after ischemic SCI. The model, based on ...
KEY FINDING: The prediction model showed fair discrimination, with an area under the ROC curve of 0.780 (95% confidence interval=0.702-0.860).
Korean J Neurotrauma, 2022 • October 1, 2022
This case report describes a 52-year-old man with cervical spinal cord injury who developed severe headache and hypertension. Initially suspected of autonomic dysreflexia, he was diagnosed with cerebr...
KEY FINDING: A patient with cervical spinal cord injury initially suspected of autonomic dysreflexia was diagnosed with cerebral venous sinus thrombosis after presenting with severe headache and hypertension.
Korean J Neurotrauma, 2022 • October 1, 2022
This study investigated the feasibility and effectiveness of overground exoskeleton-assisted gait training (OEGT) for patients with gait disorders caused by spinal stenosis. The study included five pa...
KEY FINDING: Participants showed positive changes in gait performance, balance, proximal muscle strength, psychologic state and satisfaction of rehabilitation after OEGT.
Korean J Neurotrauma, 2022 • October 1, 2022
This case report describes a 61-year-old male who developed white cord syndrome (WCS) after anterior cervical discectomy and fusion (ACDF). The patient presented with quadriplegia post-surgery, which ...
KEY FINDING: The patient developed quadriplegia immediately after anterior cervical discectomy and fusion (ACDF).
Top Spinal Cord Inj Rehabil, 2022 • October 1, 2022
This study investigates the impact of varying wheelchair axle positions on propulsion kinematics in individuals with C7 tetraplegia, focusing on speed, stroke frequency, acceleration, and shoulder ran...
KEY FINDING: Significant differences in speed were observed between axle position 1 (forward and up) and position 2 (forward and down), and between position 2 and position 4 (backward and up).