Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 3,931-3,940 of 12,052 results
BMJ Open, 2022 • October 2, 2022
This study analyzed neurological emergency admissions in England, identifying the number and types of admissions, specialist involvement, and the impact of socioeconomic deprivation. The findings reve...
KEY FINDING: Epilepsy was the most frequent neurological emergency, but only a small proportion of epilepsy admissions were managed by a neurologist.
Chinese Journal of Reparative and Reconstructive Surgery, 2022 • October 1, 2022
This study aimed to develop an anti-inflammatory PLGA scaffold by loading xanthohumol to promote cartilage regeneration. The results showed that the xanthohumol-loaded scaffolds had suitable pore size...
KEY FINDING: The xanthohumol-loaded PLGA scaffolds exhibited anti-inflammatory properties in vitro, reducing the expression of inflammatory cytokines (IL-1β and TNF-α) in macrophages.
Neuromodulation, 2022 • October 1, 2022
The study evaluated the analgesic effects of burst DRG stimulation compared to tonic stimulation in a rat model of neuropathic pain. Results indicated that burst and tonic DRG stimulation had similar ...
KEY FINDING: All waveforms tested (20 Hz-tonic, 20 Hz-burst, and 40 Hz-burst) showed similar analgesic effects in sensory tests and conditioned place preference.
J Neurosurg Spine, 2022 • October 1, 2022
This study investigates the use of Diffusion Basis Spectrum Imaging (DBSI) in combination with clinical metrics to predict outcomes of cervical decompression surgery for Cervical Spondylotic Myelopath...
KEY FINDING: The SVM trained with clinical and DBSI metrics achieved an accuracy of 88.1% and an area under the curve of 0.95 in predicting patient outcomes.
European Journal of Pain, 2022 • October 1, 2022
This study explored indicators of central sensitization in individuals with chronic neuropathic pain (NP) following spinal cord injury (SCI). Temporal summation of pain (TSP) and heat-induced sympathe...
KEY FINDING: Enhanced temporal summation of pain (TSP) was observed in SCI-NP (+66%) compared to SCI-nonNP (−75%, p = 0.009) and HC (−59%, p = 0.021).
European Journal of Pain, 2022 • October 1, 2022
This study investigated anti- and pro-nociceptive mechanisms in subjects with chronic neuropathic pain (NP) after spinal cord injury (SCI). The results do not support altered above-level anti- or pro-...
KEY FINDING: The study found no significant difference in overall pain inhibition or pain amplification between individuals with spinal cord injury-related neuropathic pain and healthy controls when testing above the level of the lesion.
Orthopaedic Surgery, 2022 • October 1, 2022
This study evaluated the effectiveness of single-door laminoplasty combined with atlantoaxial fusion for treating symptomatic atlas canal stenosis (SACS). The results showed significant improvements i...
KEY FINDING: Single-door laminoplasty combined with atlantoaxial fusion significantly increased the inner sagittal diameter of C1 and the space available for the spinal cord.
Anaesthesia, 2022 • October 1, 2022
This review addresses airway management in patients with suspected or confirmed traumatic spinal cord injury, aiming to guide best clinical practice. MILS is shown to potentially worsen laryngeal view...
KEY FINDING: Manual in-line stabilization (MILS) may worsen the laryngeal view during direct laryngoscopy, increasing the risk of failed intubation.
Chinese Journal of Reparative and Reconstructive Surgery, 2022 • October 1, 2022
This study evaluated the early clinical effectiveness of UBED combined with annulus fibrosus suture for treating LDH. The results showed significant improvements in pain and function, with a high rate...
KEY FINDING: The UBED combined with annulus fibrosus suture technique is safe and effective for treating lumbar disc herniation.
Chinese Journal of Reparative and Reconstructive Surgery, 2022 • October 1, 2022
This review examines the application and progress of UBE in treating lumbar-related diseases, covering its development, clinical uses, operative techniques, complications, and advantages. UBE is shown...
KEY FINDING: UBE is effective for lumbar spinal stenosis, providing satisfactory decompression with less damage and good lumbar stability.