Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 11,871-11,880 of 12,052 results
International Journal of Behavioral Nutrition and Physical Activity, 2007 • August 30, 2007
The study aimed to develop and evaluate the psychometric properties of the SCI Exercise Self-Efficacy Scale (ESES), a self-report measure for assessing exercise self-efficacy in individuals with spina...
KEY FINDING: The SCI Exercise Self-Efficacy Scale (ESES) demonstrated high internal consistency, with a Cronbach's alpha of .9269 in a large sample.
Journal of NeuroEngineering and Rehabilitation, 2007 • August 21, 2007
The purpose of this study was to determine how manual assistance affected lower limb electromyographic activity and joint kinematics in higher-level subjects with incomplete spinal cord injury during ...
KEY FINDING: Manual assistance does not significantly alter muscle activation profiles in individuals with spinal cord injury during treadmill training.
The Journal of Neuroscience, 2007 • August 15, 2007
This study demonstrates that spinal cord injury (SCI) induces microglial activation in the ventral posterolateral (VPL) nucleus of the thalamus, a brain region involved in pain processing. The chemoki...
KEY FINDING: CCL21 is upregulated in dorsal horn neurons and tissue levels are increased in the dorsal horn and VPL nucleus of the thalamus 4 weeks after SCI.
Dev Neurobiol, 2007 • August 1, 2007
This paper reviews the challenges of translating preclinical research on neural repair, particularly for stroke and spinal cord injury, into effective clinical therapies. It emphasizes the limitations...
KEY FINDING: Rodent models of neural repair for stroke and spinal cord injury have limitations due to differences in brain size, axonal regeneration distances, and immune responses compared to humans.
Exp Neurol, 2007 • August 1, 2007
The study investigates the physiological properties of regenerated sensory axons in the dorsal columns after spinal cord injury (SCI) in rats. It was found that regenerated axons, six months post-inju...
KEY FINDING: Regenerated axons had reduced conduction velocity compared to intact axons.
The Journal of Neuroscience, 2007 • July 25, 2007
This study investigates the role of ATF3, a transcription factor induced by peripheral nerve injury, in promoting nerve regeneration. The researchers generated transgenic mice that constitutively expr...
KEY FINDING: ATF3 enhances the rate of peripheral nerve regeneration to an extent comparable to a preconditioning nerve injury.
Journal of NeuroEngineering and Rehabilitation, 2007 • July 10, 2007
The study introduces a novel moveable clinical device intended for functional rehabilitation of strength and balance, allowing mediolateral APAs to occur across a wide range of gravity-like loads, whi...
KEY FINDING: Combined strength and balance training in a tilted virtual environment improves upright balance function and muscular strength.
The Journal of Neuroscience, 2007 • July 4, 2007
This study demonstrates that Schwann cells (SCs) and olfactory ensheathing cells (OECs) differentially interact with astrocytes, influencing astrocytosis following CNS injury. SC-conditioned media (SC...
KEY FINDING: Schwann cell-conditioned media induces reactive astrocytosis and boundary formation in OEC/astrocyte cocultures, sensitive to FGFR1 inhibition.
Neurorehabil Neural Repair, 2007 • July 1, 2007
This study compared walking speeds in patients with incomplete SCI using a 15.2-m walk and a 6-minute walk, finding no significant difference in speed at 3 and 6 months post-injury. At 12 months, pati...
KEY FINDING: The mean speed for the 15.2-m walk did not differ from that used for the 6-minute walk at 3 and 6 months.
Glia, 2007 • July 1, 2007
This study investigates the potential of exercise to overcome the inhibitory effects of myelin on neuronal growth in the central nervous system. The findings demonstrate that exercise reduces the inhi...
KEY FINDING: Exercise reduces the levels of myelin-associated glycoprotein (MAG) in the spinal cord, a potent axonal growth inhibitor.