Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 11,811-11,820 of 12,052 results
Exp Neurol, 2008 • June 1, 2008
This study demonstrates that treadmill exercise, even in small amounts, enhances axon regeneration in the peripheral nervous system after injury. Both continuous, low-intensity training (CT) and high-...
KEY FINDING: Treadmill exercise, even in small doses, enhances axon regeneration in the peripheral nervous system.
Molecular & Cellular Proteomics, 2008 • May 14, 2008
This study demonstrates that aFGF is able to induce effective functional recovery after contusive spinal cord injury in rats. This was achieved through a single injection of aFGF. Proteomics analysis ...
KEY FINDING: aFGF treatment induces functional recovery of locomotion in contusive SCI rats, as demonstrated by improved BBB scores and CBS analysis.
Osteoporos Int, 2008 • May 1, 2008
Spinal cord injury (SCI) causes severe bone loss due to increased bone resorption and decreased bone formation. The study utilized a clinically relevant contusion model of experimental spinal cord inj...
KEY FINDING: A significant decrease in bone mineral density (34%) was observed at the distal femoral metaphysis in injured rats compared to controls just 10 days post-injury.
Arch Phys Med Rehabil, 2008 • May 1, 2008
This study compared the effectiveness of different electrical stimulation strategies (progressively increasing intensity, frequency, or both) on maintaining paralyzed quadriceps muscle force during re...
KEY FINDING: Progressively increasing both stimulation intensity and frequency generated more successful contractions than progressively increasing the frequency followed by intensity.
Exp Neurol, 2008 • May 1, 2008
This study investigated the efficacy of microinjecting ChABC directly into the injury site in a rat model of spinal cord injury, using a peripheral nerve graft (PNG) to bridge the injury. The results ...
KEY FINDING: Microinjection of ChABC resulted in extensive CSPG digestion around the injury site.
Journal of NeuroEngineering and Rehabilitation, 2008 • April 26, 2008
The study aimed to investigate the biomechanics of the hip, knee, and ankle during progressive resistance cycling in SCI subjects to detect and measure muscle fatigue, hypothesizing that knee power ou...
KEY FINDING: Ankle and knee power outputs decreased with increasing resistance, while hip power output increased.
The Journal of Neuroscience, 2008 • April 9, 2008
This study used a dual-lesion paradigm in cats to investigate the role of the spinal central pattern generator (CPG) in the recovery of locomotion after partial spinal cord injuries (SCI). The researc...
KEY FINDING: Cats with partial SCI that received treadmill training exhibited immediate bilateral hindlimb locomotion after complete spinal cord transection, indicating that the spinal CPG was primed for locomotion.
The Journal of Neuroscience, 2008 • April 9, 2008
The study examined myelin status in spared axons after spinal cord injury in mice, finding that these axons are largely remyelinated by 12 weeks post-injury. This indicates a positive correlation betw...
KEY FINDING: Spared rubrospinal tract (RST) axons of passage were fully remyelinated 12 weeks after mouse spinal cord contusion injury.
The Journal of Neuroscience, 2008 • April 2, 2008
This study demonstrates that it is possible to inhibit glial scar formation and to facilitate regeneration after SCI using bioactive three-dimensional nanostructures displaying high densities of neuro...
KEY FINDING: Treatment with IKVAV PA after SCI reduced astrogliosis.
Am J Respir Crit Care Med, 2008 • April 1, 2008
This study assessed relationships between clinical factors and longitudinal change in FEV1 and FVC in chronic SCI. After adjusting for stature and age, significant determinants of longitudinal decline ...
KEY FINDING: Longitudinal change in FEV1 and FVC was not directly related to level and severity of SCI.