Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 11,761-11,770 of 12,052 results
Spinal Cord, 2008 • November 1, 2008
The purpose of this study was to examine the effects of FES-LCE training on systemic arterial compliance in persons with SCI. This investigation revealed for the first time that FES-LCE is effective i...
KEY FINDING: There was no significant change in large artery compliance after FES-LCE training.
J Mol Neurosci, 2008 • November 1, 2008
Vasoactive intestinal polypeptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP) are expressed in the neural pathways regulating the lower urinary tract. VIP-immunoreactivity (IR...
KEY FINDING: Exogenously applied VIP relaxes bladder and urethral smooth muscle and excites parasympathetic neurons in bladder ganglia.
Exp Neurol, 2008 • November 1, 2008
This study investigated the effects of TGF-α infusion on astrocyte response and axonal growth following spinal cord injury in mice. TGF-α modified the physical hurdle of the scar by transforming the a...
KEY FINDING: TGF-α infusion promoted extensive axon growth into the lesion site following spinal cord injury in mice.
Exp Neurol, 2008 • November 1, 2008
The study investigates the effects of lumbosacral ventral root avulsion (VRA) injury and re-implantation on the morphology of the rat bladder at twelve weeks post-operatively. VRA injury caused a thin...
KEY FINDING: VRA injury leads to overall thinning of the bladder wall, reduced thickness of the lamina propria and smooth muscle, and increased thickness of the bladder epithelium.
Neurobiol Dis, 2008 • November 1, 2008
This study investigated the effects of Niaspan on EAE mice, demonstrating that Niaspan treatment significantly improves neurological functional recovery. This recovery is potentially mediated by the r...
KEY FINDING: Niaspan treatment significantly increased neurological functional recovery in EAE mice compared to controls.
Journal of NeuroEngineering and Rehabilitation, 2008 • October 28, 2008
This study evaluated the reliability of a novel method for assessing isometric muscle force of leg muscles using the Lokomat, a driven gait orthosis (DGO). Inter- and intra-rater reliability were dete...
KEY FINDING: The study demonstrated fair to good inter- and intra-rater reliability for measuring isometric muscle force in the lower extremities using the Lokomat in subjects with and without neurological movement disorders.
Cell Mol Neurobiol, 2009 • October 17, 2008
The study successfully cloned the full-length PDGF-C gene from Gekko japonicus and analyzed its sequence, revealing similarities to PDGF-C in other species. Expression analysis showed that PDGF-C is w...
KEY FINDING: The PDGF-C gene of Gekko japonicus was cloned and found to have a transcript size of 2.8 kb.
Neuroscience, 2008 • October 15, 2008
The MRL/MpJ mouse strain, known for its regenerative abilities, was studied after spinal cord injury to see if it would result in reduced scar formation, increased axonal growth, and improved function...
KEY FINDING: MRL/MpJ mice exhibited robust axon growth within the lesion, beginning at 4 weeks post-injury.
Journal of Neuroinflammation, 2008 • October 15, 2008
The study investigates the effect of TMEV infection on inflammation and neurogenesis in the SVZ, a key area for brain repair. Results indicated that forebrain CD45+ cell activation precedes spinal cor...
KEY FINDING: CD45+ cell activation occurs early in the forebrain after TMEV infection, with the SVZ showing the most consistent activation.
Journal of Biology, 2008 • October 15, 2008
The review discusses the concept of using cellular bridges to repair spinal cord injuries, focusing on the challenges and potential of using different types of glial cells. It highlights research iden...
KEY FINDING: Certain astrocytes derived from glial-restricted precursors treated with BMP-4 promote spinal cord repair by integrating into host tissue, suppressing scar formation, and encouraging axon regeneration.