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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Latest Research Summaries

Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.

Showing 11,701-11,710 of 12,052 results

Assistive TechnologyRehabilitationBiomedical

Infrared thermography as an access pathway for individuals with severe motor impairments

Journal of NeuroEngineering and Rehabilitation, 2009 • April 16, 2009

The study investigates infrared thermography as a non-invasive access pathway for individuals with motor impairments, focusing on detecting mouth opening and closing. A thermal camera and computerized...

KEY FINDING: The study achieved high detection sensitivity and low error rates in detecting mouth opening and closing using infrared thermography.

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AgingNeurology

Age-related myelin dynamics revealed by increased oligodendrogenesis and short internodes

Aging Cell, 2009 • April 1, 2009

This study characterized myelin changes within the murine rubrospinal tract and found that internode lengths significantly decrease as a function of age which suggests active remyelination. The data r...

KEY FINDING: Internode lengths of rubrospinal tract axons significantly decrease with age, suggesting active remyelination.

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Spinal Cord InjuryParticipationRehabilitation

Physical activity is related to lower levels of pain, fatigue, and depression in individuals with spinal cord injury: A correlational study

Spinal Cord, 2009 • April 1, 2009

This study provides an evaluation of the level and nature of physical activity among a cohort of individuals with SCI. Demographic factors measured in this study (sex, age, time since injury, and lesi...

KEY FINDING: Approximately 50% of reported physical activity among individuals with SCI is due to activities of daily living.

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Spinal Cord InjuryNeurologyRehabilitation

A Systematic Review of the Management of Autonomic Dysreflexia Following Spinal Cord Injury

Arch Phys Med Rehabil, 2009 • April 1, 2009

This systematic review evaluates clinical evidence on strategies to prevent and manage autonomic dysreflexia (AD) following spinal cord injury (SCI). The review included 31 studies, with the majority ...

KEY FINDING: Preventative strategies for AD triggered by common stimuli (e.g., urogenital system) are primarily supported by Level 4 and Level 5 evidence.

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Spinal Cord InjuryGeneticsBiomedical

Local gene delivery from ECM coated poly (lactide co glycolide) multiple channel bridges after spinal cord injury

Biomaterials, 2009 • April 1, 2009

This study investigates surface immobilization to deliver complexed DNA (lipoplexes) from a multiple channel bridge in order to promote transgene expression in the injured spinal cord using low quanti...

KEY FINDING: Fibronectin, an ECM protein, produced greater gene expression levels and immobilization efficiencies compared with collagen and laminin.

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Spinal Cord InjuryCardiovascular Science

Permanent cardiac pacemaker for cardiac arrest following cervico-dorsal spinal injury

Eur Spine J, 2009 • March 28, 2009

This case report describes a 47-year-old male who suffered a traumatic C7–D1 dislocation and experienced severe bradycardia with multiple episodes of cardiac arrest for two months post-injury. Despite...

KEY FINDING: A patient with a cervico-dorsal (C7-D1) spinal injury experienced persistent and recurrent cardiac arrests that did not resolve within the expected 4-6 weeks.

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ImmunologyNeurologyGenetics

Macrophages Promote Axon Regeneration with Concurrent Neurotoxicity

The Journal of Neuroscience, 2009 • March 25, 2009

This study demonstrates that activated macrophages can simultaneously promote axon regeneration and neurotoxicity in the CNS. Zymosan-activated macrophages (ZAMs) initially enhance axon growth towards...

KEY FINDING: Activated macrophages (ZAMs) increase axon growth towards macrophage foci in the spinal cord, indicating a pro-regenerative effect.

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Spinal Cord InjuryNeurologyDermatology

A quantitative skin impedance test to diagnose spinal cord injury

Eur Spine J, 2009 • March 20, 2009

The study aimed to develop a quantitative skin impedance test to diagnose spinal cord injury (SCI), particularly in unconscious or non-cooperative patients. Skin impedance measurements were taken at s...

KEY FINDING: The artificial neural network (ANN) could classify traumatic SCI patients with a success rate of 73% when using skin impedance values.

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Regenerative MedicineGeneticsDermatology

Connexin43 carboxyl-terminal peptides reduce scar progenitor and promote regenerative healing following skin wounding

Regen Med, 2009 • March 1, 2009

The study demonstrates that a Cx43 carboxyl-terminal peptide (ACT1) can accelerate wound closure and improve the quality of skin healing in both mouse and pig models. ACT1 treatment leads to reduced i...

KEY FINDING: Cx43 CT-peptide prompted decreases in area of scar progenitor tissue and promoted restoration of dermal histoarchitecture and mechanical strength following wounding of skin.

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Spinal Cord InjuryNeurologyRehabilitation

Treadmill training enhances the recovery of normal stepping patterns in spinal cord contused rats

Exp Neurol, 2009 • March 1, 2009

The study examined the effect of treadmill training on locomotor recovery in rats with severe spinal cord contusions, comparing trained and untrained groups using a robotic device for training and ass...

KEY FINDING: Spinal cord contused rats can generate partial weight bearing stepping in the absence of treadmill training.

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