Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 11,691-11,700 of 12,052 results
Med Biol Eng Comput, 2009 • May 1, 2009
This paper introduces a feedforward–feedback controller for a two-joint, six-muscle arm model, designed for functional electrical stimulation (FES) systems. The controller incorporates an artificial n...
KEY FINDING: The combined feedforward-feedback controller achieved a tracking error of less than 4° in ideal conditions.
Arch Phys Med Rehabil, 2009 • May 1, 2009
This study evaluated the use of lower thoracic spinal cord stimulation (SCS) to restore cough function in patients with tetraplegia. The researchers hypothesized that SCS would activate expiratory mus...
KEY FINDING: Lower thoracic spinal cord stimulation (SCS) can effectively activate expiratory muscles in individuals with tetraplegia.
Arch Phys Med Rehabil, 2009 • May 1, 2009
This study evaluated the precision of dual energy x-ray absorptiometry (DXA) scanning at the distal femur and proximal tibia in individuals with spinal cord injury (SCI). The study found that precisio...
KEY FINDING: The root mean square coefficient of variation (RMS-CV) at the distal femur was 3.01%, and the root mean standard deviation (RMS-SD) was 0.025 g/cm2.
Arch Phys Med Rehabil, 2009 • May 1, 2009
This systematic review assessed the evidence for managing orthostatic hypotension (OH) in individuals with spinal cord injuries (SCI). The review identified 8 pharmacological and 21 non-pharmacologica...
KEY FINDING: Only one low-quality randomized controlled trial (RCT) supported the use of midodrine for OH management following SCI, providing Level 2 evidence.
JOURNAL OF NEUROTRAUMA, 2009 • May 1, 2009
This study examined the impact of forced exercise on recovery after a unilateral cervical spinal cord contusion injury in rats, focusing on forelimb and hindlimb function, spinal cord biochemistry, an...
KEY FINDING: Forced exercise led to a transient improvement in fore and hind limb function during weeks 2–4 following a cervical spinal cord injury.
Neuroimage, 2009 • May 1, 2009
This study investigated the use of quantitative MRI techniques (qT2 and MTR) to assess demyelination and remyelination in a mouse model of multiple sclerosis. Lysolecithin was injected into the spinal...
KEY FINDING: The myelin water fraction (MWF) and geometric mean T2 value significantly decreased at 14 days post-injection, indicating demyelination. By 28 days, these values returned to control levels, suggesting remyelination.
The Journal of Neuroscience, 2009 • April 29, 2009
This study demonstrates that α9 integrin expression promotes neurite outgrowth on tenascin-C (TN-C) both in vitro and in vivo, suggesting a potential therapeutic strategy for enhancing axon regenerati...
KEY FINDING: Expression of α9 integrin in PC12 cells and adult rat DRG neurons promotes extensive neurite outgrowth on tenascin-C in vitro.
PNAS, 2009 • April 28, 2009
The study investigates methods to induce regeneration of corticospinal axons, which are crucial for motor function but typically do not regenerate after injury. The researchers hypothesized that enhan...
KEY FINDING: Overexpression of trkB in layer V motor cortex in vivo induces axonal regeneration after subcortical axotomy.
Eur Spine J, 2009 • April 24, 2009
The study presents results of surgical treatment for thoracolumbar flexion-distraction fractures in young patients caused by motor vehicle crashes, focusing on function, pain, and neurological recover...
KEY FINDING: Fusion was achieved in all patients at follow-up, and clinical condition was satisfactory with absence of significant pain, indicating mechanical stability.
BMC Neuroscience, 2009 • April 20, 2009
This study aimed to evaluate the effect of electro-acupuncture (EA) on the survival and differentiation of bone marrow mesenchymal stem cell (MSC) transplantation, axonal regeneration, and functional ...
KEY FINDING: The combination of MSC transplantation and EA treatment significantly increased cAMP and NT-3 levels in the injured spinal cord compared to MSC transplantation or EA treatment alone.