Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 11,471-11,480 of 12,052 results
Int J Dev Neurosci, 2010 • October 1, 2010
This study investigates the temporal profile of the P2Y2 nucleotide receptor after spinal cord injury (SCI) in adult female Sprague–Dawley rats, focusing on its role in the pathophysiology response ge...
KEY FINDING: P2Y2 mRNA significantly increased after 2 days post-injury and remained elevated for 28 days.
Molecular Therapy, 2010 • October 1, 2010
The study investigates the role of tenascin-C (TNC) in spinal cord regeneration using TNC-deficient mice and wild-type controls after spinal cord injury. The findings indicate that TNC deficiency impa...
KEY FINDING: TNC-deficient mice exhibit impaired locomotor recovery after spinal cord injury compared to wild-type mice.
Spinal Cord, 2010 • October 1, 2010
The study aimed to determine whether the SRT is a valid and reliable measure of seated postural control in individuals with MISCI, comparing it with COPE and trunk excursion. Results showed that both ...
KEY FINDING: The SRT was correlated with COPE in three directions (forward, right, and backward) of reaching, except for leftward reaching in MISCI subjects.
Clin Neurophysiol, 2010 • October 1, 2010
Spinal motoneurons are the final neural output of the central nervous system (CNS) through which motor commands to peripheral muscles are communicated. The level of the monoaminergic drive from the br...
KEY FINDING: The motoneuronal PIC recovers after chronic SCI, restoring motoneuronal excitability and contributing to long-lasting reflexes and muscle spasms.
Ultrasound Med Biol, 2010 • October 1, 2010
This study evaluated the reliability and responsiveness of musculoskeletal ultrasound (US) in assessing muscle and tendon characteristics in individuals with and without spinal cord injury (SCI). The ...
KEY FINDING: Ultrasound detected muscle hypertrophy (p < 0.05) following electrical stimulation training in subjects with SCI (responsiveness), but did not detect differences in tendon thickness.
PM R, 2010 • October 1, 2010
This cross-sectional study examined the prevalence of shoulder pain and its association with mobility devices in individuals with chronic SCI. The study found a high prevalence of shoulder pain (39.8%...
KEY FINDING: Shoulder pain was reported by 39.8% of participants, making it the third most common site of pain after the legs and back.
Brain, 2010 • September 17, 2010
The study introduces a novel mouse model of CNS demyelination achieved through cell-specific activation of diphtheria toxin A (DT-A) expression in adult oligodendrocytes. This leads to widespread olig...
KEY FINDING: The study successfully generated a mouse model with inducible oligodendrocyte ablation in adulthood, leading to demyelination.
Journal of NeuroEngineering and Rehabilitation, 2010 • September 17, 2010
The study introduces dipolar cortico-muscular stimulation (dCMS), a novel electrical stimulation technique involving the application of negative voltage to the muscle and positive voltage to the motor...
KEY FINDING: In SCI animals, dCMS significantly improved cortically-elicited muscle contraction at both the contralateral (456%) and ipsilateral (457%) gastrocnemius muscles, with the improvement lasting for at least 60 minutes.
BMC Neuroscience, 2010 • September 16, 2010
The study investigated the effects of hMSC transplantation on neurogenic bladder and locomotor function recovery in rats with spinal cord injury, also examining the relationship with endogenous neurot...
KEY FINDING: hMSC transplantation reduced ED1 positive macrophages (inflammatory response) in the injured spinal cord compared to control groups.
Journal of NeuroEngineering and Rehabilitation, 2010 • September 10, 2010
This study investigates the immediate effects of patient-cooperative versus non-cooperative robot-aided gait training on individuals with incomplete spinal cord injury (iSCI). The results indicate tha...
KEY FINDING: Patients showed more spatial and temporal kinematic variability in the patient-cooperative path control mode with individually adjusted support.