Browse the latest research summaries in the field of women's health for spinal cord injury patients and caregivers.
Showing 51-60 of 60 results
PM R, 2019 • August 1, 2019
This population-based study examined pregnancy, delivery, and neonatal outcomes for women with SCI, paralysis, and SB. Infants of women with these conditions did not experience greater risk of longer-...
KEY FINDING: Women with SCI, paralysis, or SB had increased risks of prenatal urinary tract infection/pyelonephritis.
Journal of International Medical Research, 2019 • July 1, 2019
This case report presents a 35-year-old woman with a spinal cord injury (SCI) who developed autonomic dysreflexia (AD) during pregnancy, which resolved after delivery. The patient, with a T4 AIS-A SCI...
KEY FINDING: The patient developed new onset autonomic dysreflexia (AD) during pregnancy, characterized by increased need to empty her bladder, facial flushing, palpitation, sweating, and headache.
Spinal Cord Series and Cases, 2019 • May 5, 2019
This study examined the relationship between hormone levels (testosterone and TSH) and depressive symptoms in women with SCI. It aimed to address a gap in research focusing on women's unique health co...
KEY FINDING: Low total testosterone was observed in 20% of the participants, and this was associated with increased depressive symptoms after accounting for time from injury.
Top Spinal Cord Inj Rehabil, 2012 • January 1, 2012
This study provides preliminary evidence that women with SCI may have comparable trends in CMR as those observed in nondisabled women of similar menopausal status. The study found that postmenopausal ...
KEY FINDING: Postmenopausal women with SCI had significantly higher triglyceride levels compared to premenopausal women (101.8 mg/dL vs 55.7 mg/dL, P = .01).
Stem Cell Research & Therapy, 2022 • August 3, 2022
This study investigates the therapeutic potential of intra-amniotic transplantation of brain-derived neurotrophic factor (BDNF)-modified bone marrow mesenchymal stem cells (BMSCs) for rat fetuses with...
KEY FINDING: BDNF-BMSCs sustained the characteristic of directional migration, engrafted at the SBA lesion area, increased the expression of BDNF in the defective spinal cords, alleviated the apoptosis of spinal cord cells, differentiated into neurons and skin-like cells, reduced the area of skin lesions, and improved the amniotic fluid microenvironment.
Stem Cell Research & Therapy, 2024 • February 7, 2024
This study explored the heterogeneity of human UC-MSCs and identified the LRP1high subpopulation as capable of improving ovarian function in aged and POF mice. The LRP1high subpopulation improves ov...
KEY FINDING: Human UC-MSCs can be divided into three subtypes: mesenchymal stem cells, multilymphoid progenitor cells, and trophoblasts.
Cell Reports Medicine, 2024 • May 21, 2024
The study analyzes the transcriptome and DNA methylome of fetal germline cells following maternal SARS-CoV-2 infection, finding that infection at early gestational age trivially affects fetal germ cel...
KEY FINDING: Maternal SARS-CoV-2 infection has trivial impacts on fetal germ cell (FGC) development during early gestation, a critical period for germ cell specification and epigenetic reprogramming.
Molecular Therapy: Methods & Clinical Development, 2024 • June 1, 2024
This study investigated the safety and efficacy of prenatal AAV9-GFP administration in fetal lambs for potential treatment of neuromuscular disorders. The results showed broad biodistribution and tran...
KEY FINDING: Umbilical vein injection of AAV9-GFP resulted in widespread biodistribution in lamb tissues and maternal uteruses.
Journal of Molecular Medicine, 2020 • December 20, 2019
This study investigates the role of platelet-derived factors on placental βhCG synthesis. It demonstrates that maternal platelets can be detected at the early maternal-fetal interface and that platele...
KEY FINDING: Maternal platelets can be detected on the surface of placental villi and in intercellular gaps of trophoblast cell columns from gestational week 5 onwards.
Archives of Public Health, 2020 • March 24, 2020
This study assessed vitamin D deficiency prevalence in 34,417 pregnant women in Shanghai between 2014 and 2017. The study found a high prevalence of vitamin D deficiency among these women. Vitamin D l...
KEY FINDING: A large majority (98.4%) of pregnant women in Shanghai did not have adequate vitamin D levels, with 70% being severely deficient or deficient.