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  4. Prevalence of vitamin D deficiency in the pregnant women: an observational study in Shanghai, China

Prevalence of vitamin D deficiency in the pregnant women: an observational study in Shanghai, China

Archives of Public Health, 2020 · DOI: https://doi.org/10.1186/s13690-020-00414-1 · Published: March 24, 2020

EndocrinologyWomen's HealthPublic Health

Simple Explanation

Vitamin D is important for calcium and bone health, and also affects the immune system, blood production, cancer development, glucose control and brain function. Therefore, vitamin D deficiency can lead to various diseases. This study examined vitamin D levels in pregnant women in Shanghai, China, and found that most of them had insufficient levels of vitamin D. The study also looked at whether low vitamin D levels were linked to gestational diabetes or low birth weight. The study found that vitamin D levels varied by season and age, with winter and older age groups showing slightly higher levels. However, there was no link between vitamin D deficiency and gestational diabetes or low birth weight in this study population.

Study Duration
January 2014 to December 2017
Participants
34,417 pregnant women in Shanghai
Evidence Level
Observational study

Key Findings

  • 1
    A large majority (98.4%) of pregnant women in Shanghai did not have adequate vitamin D levels, with 70% being severely deficient or deficient.
  • 2
    Vitamin D levels varied significantly by season, with the highest levels observed in winter and the lowest in summer.
  • 3
    Older pregnant women (>35 years) tended to have higher vitamin D levels compared to younger women.

Research Summary

This study assessed vitamin D deficiency prevalence in 34,417 pregnant women in Shanghai between 2014 and 2017. The study found a high prevalence of vitamin D deficiency among these women. Vitamin D levels were influenced by season and age, but no association was found between vitamin D deficiency and gestational diabetes or low birth weight. The findings suggest a need for vitamin D supplementation among pregnant women in Shanghai to improve vitamin D status and potentially prevent related complications.

Practical Implications

Vitamin D Supplementation

The study suggests that most pregnant women in Shanghai may need vitamin D supplementation to achieve adequate vitamin D levels.

Targeted Interventions

Given the seasonal variations, interventions could be targeted during summer months when vitamin D levels are lowest.

Further Research

Further research is needed to determine an appropriate vitamin D intake guideline during gestation in China.

Study Limitations

  • 1
    Lack of demographic details, including sunlight exposure status and vitamin D supplement intake.
  • 2
    Potential inaccuracies in 25(OH)D level detection due to the Roche assay used.
  • 3
    Absence of an external quality control for detecting 25(OH)D level with Roche assay.

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