Browse the latest research summaries in the field of veterinary medicine for spinal cord injury patients and caregivers.
Showing 51-60 of 90 results
BMC Veterinary Research, 2021 • March 19, 2021
This study aimed to quantify static weight distribution (SWD) in neurologically normal, mature, chondrodystrophic small breed dogs using digital scales and to establish the feasibility of different sc...
KEY FINDING: Using two digital bathroom scales (B2) was the simplest and most reliable technique, and resulted in a thoracic limb to pelvic limb SWD of 63–37 %.
Frontiers in Veterinary Science, 2021 • March 12, 2021
Inactivity and bed rest have deleterious effects on various body systems, particularly the musculoskeletal system, in veterinary patients with spinal cord injury. Physical rehabilitation can help reve...
KEY FINDING: Inactivity leads to muscle atrophy, with muscle strength decreasing significantly, even more than the degree of atrophy observed.
Acta Vet Scand, 2021 • April 27, 2021
The review explores the history, biophysics, neurophysiology and parameters of the following neuromodulation modalities: FES, TESCS, and TDCS. Both human and small animal patients with SCI can benefit...
KEY FINDING: Functional electrical stimulation (FES) can be used to strengthen muscles, improve blood flow, and avoid progression of muscle atrophy in companion animals.
Open Veterinary Journal, 2021 • June 4, 2021
This study evaluates the use of autologous bone marrow-derived stromal cells in platelet-rich plasma for treating chronic spinal cord injuries in dogs and cats via a one-time combined intrathecal/intr...
KEY FINDING: The combined intrathecal/intravenous injection of bone marrow stromal cells is a safe and promising procedure for treating chronic spinal cord injuries in companion animals.
Journal of Feline Medicine and Surgery Open Reports, 2020 • April 2, 2020
This case report describes the successful use of intramuscular botulinum toxin type A (BTX-A) to treat severe muscle contractures in a 4-month-old cat following a spinal cord injury. The cat developed...
KEY FINDING: Intramuscular BTX-A injection was effective in treating acquired muscle contractures in a cat secondary to spinal cord injury.
Int. J. Mol. Sci., 2022 • October 4, 2022
This study evaluated the therapeutic potential of a selective calpain inhibitor (PD150606) in combination with methylprednisolone sodium succinate (MPSS) in a dog SCI model. The findings revealed that...
KEY FINDING: The combined administration of MPSS+PD150606 demonstrated considerably lower neuronal loss and microglial cell infiltration than the other groups, with a significant improvement in the locomotor score.
Animals, 2022 • December 18, 2022
Locomotor training is a strategy for functional neurorehabilitation that promotes relearning of stepping, leading to coordinated ambulation, applicable to various neurological diseases including spina...
KEY FINDING: Early treadmill training after SCI promotes muscle electromyography signal increase and modulates activity, correlating with motor recovery.
Neurourol Urodyn, 2017 • January 1, 2017
This study investigated vagal nerve sprouting to the bladder and clitoris in a canine model of lower motoneuron lesioned bladder. The researchers performed nerve transfer surgeries in female hounds an...
KEY FINDING: Increased detrusor pressure was seen in nerve transfer animals after functional electrical stimulation (FES).
J Neurosci Methods, 2016 • August 1, 2016
The study adapted the Basso–Beattie–Bresnahan (BBB) locomotor rating scale for use in dogs with spinal cord injury (SCI), creating the canine BBB (cBBB) scale. The cBBB was found to be highly responsi...
KEY FINDING: The original BBB locomotor rating scale requires modification for use in dogs due to differences in normal locomotion between rats and dogs.
Journal of Visualized Experiments, 2016 • July 29, 2016
This protocol describes a detailed implementation of a novel JAVA platform AD Detection software which would be combined with a telemetry device, for a long-term thorough analysis of ABP in SCI-animal...
KEY FINDING: The software characterizes spontaneous AD events by an increase in SBP greater than 20 mmHg accompanied by a decrease in HR of 40 bpm or greater.