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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Surgery Research

Browse the latest research summaries in the field of surgery for spinal cord injury patients and caregivers.

Showing 551-560 of 614 results

SurgeryTraumaOrthopedics

Application of Collagen-Based Scaffolds for the Treatment of Spinal Cord Injuries in Animal Models: A Literature Update

Cureus, 2022 • June 16, 2022

This review compiles recent data on collagen scaffolds for treating SCI in animal models. SCI presents significant challenges due to its economic and psychological impact. Studies using animals with s...

KEY FINDING: Collagen-based scaffolds, when transplanted, showed the most proliferation, and neural stem and progenitor cells survived up to 11 weeks after the transplant.

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HealthcareSurgeryBioinformatics

Performance of Artificial Intelligence-Based Algorithms to Predict Prolonged Length of Stay after Lumbar Decompression Surgery

J. Clin. Med., 2022 • July 13, 2022

This study investigates the application of artificial intelligence-based algorithms to predict prolonged hospital length of stay (LOS) after lumbar decompression surgery. The findings suggest that mac...

KEY FINDING: Machine learning and deep learning algorithms can predict whether patients will experience an increased LOS following lumbar decompression surgery.

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PharmacologySurgeryOrthopedics

The Effect of Amniotic Tissue on Spinal Interventions: A Systematic Review

International Journal of Spine Surgery, 2022 • October 12, 2022

This systematic review summarizes the existing literature regarding the use of amniotic membrane preparations, treatment regimens, and indications within spinal surgery. The review of reported studies...

KEY FINDING: Amnion products show promising effects in reducing epidural adhesions and scar tissue after spine surgery.

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Spinal Cord InjurySurgeryBiomedical

Building a Stronger Backbone: 3D Printing’s Role in Treating Spinal Cord Conditions

Asian J Neurosurg, 2024 • September 3, 2024

This systematic review explores the use of 3D printing (3DP) in treating spinal cord injuries (SCIs), assessing its cost, efficacy, safety, and technological constraints. The review analyzed 11 studie...

KEY FINDING: 3DP technologies are showing positive results in treating SCIs and have the potential to improve both surgical and non-surgical treatments.

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SurgeryBiomedical

Cervical subtotal discectomy prosthesis validated in non-human primate model: A novel artificial cervical disc replacement concept?

Frontiers in Bioengineering and Biotechnology, 2022 • October 13, 2022

The study evaluated a novel cervical subtotal discectomy prosthesis (CSDP) in a non-human primate model, focusing on its safety, osseointegration, and biomechanical stability. The CSDP demonstrated ex...

KEY FINDING: The CSDP constituent titanium alloy (Ti6Al4V-AO) showed extended adhesion, remarkable viability status, and cell proliferation when co-cultured with mouse embryo osteoblast precursor cells.

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SurgeryOrthopedicsResearch Methodology & Design

Full‑endoscopic versus conventional microsurgical therapy of lumbar disc herniation: a prospective, controlled, single‑center, comprehensive cohort trial (FEMT‑LDH trial)

Trials, 2022 • November 3, 2022

This study protocol outlines a comprehensive cohort trial comparing full-endoscopic and microsurgical techniques for lumbar disc herniation treatment. The study includes a randomized and a non-randomi...

KEY FINDING: The study aims to compare the results of lumbar discectomies using the full-endoscopic technique via the interlaminar and trans-foraminal access with those of the conventional microsurgical technique, particularly with regard to iatrogenic muscle trauma and patient-related outcome measures.

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SurgerySpinal Disorders

Correlation between direction of pedicle screw and restoration of lumbar degenerative scoliosis in degenerative lumbar spondylolisthesis: a retrospective study

Quantitative Imaging in Medicine and Surgery, 2023 • March 1, 2023

This retrospective study analyzed 57 patients with degenerative lumbar spondylolisthesis (DLS) and lumbar degenerative scoliosis who underwent single-level unilateral transforaminal lumbar interbody f...

KEY FINDING: TLIF surgery appears effective in improving radiographic and clinical outcomes for patients with DLS and lumbar degenerative scoliosis.

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SurgeryOrthopedicsMusculoskeletal Medicine

Minimally invasive plate osteosynthesis (MIPO) for distal humeral fractures: a cadaveric study and first clinical application

BMC Musculoskeletal Disorders, 2023 • March 28, 2023

This study investigated the feasibility of minimally invasive plate osteosynthesis (MIPO) for treating distal humeral fractures, including both extra-articular and intra-articular types. The researche...

KEY FINDING: Reduction and plate fixation of all distal humeral fractures (8 cadaveric) with and without osteotomy was feasible.

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SurgeryBiomedical

Multi-modulation of immune-inflammatory response using bioactive molecule-integrated PLGA composite for spinal fusion

Materials Today Bio, 2023 • March 14, 2023

This study introduces a bioactive molecule-laden PLGA composite (PME2/PN) designed for multi-modulation of bone fusion, addressing limitations in current bone substitute technologies. The PME2/PN comp...

KEY FINDING: The PME2/PN composite significantly improved osteogenic and angiogenic gene expression, crucial for bone fusion.

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NeurologySurgerySpinal Disorders

Increased blood flow of spinal cord lesion after decompression improves neurological recovery of degenerative cervical myelopathy: an intraoperative ultrasonography-based prospective cohort study

International Journal of Surgery, 2023 • March 31, 2023

The study aimed to evaluate spinal cord blood flow status after sufficient decompression by intraoperative contrast-enhanced ultrasonography (CEUS) and to analyze the correlation between neurological ...

KEY FINDING: Intraoperative CEUS can clearly reflect spinal cord blood flow in DCM patients.

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