Browse the latest research summaries in the field of spinal disorders for spinal cord injury patients and caregivers.
Showing 11-20 of 159 results
Journal of Orthopaedic Surgery and Research, 2025 • January 16, 2025
This study investigated the impact of simulated overload and microgravity on intervertebral disc degeneration in rabbits. The researchers focused on the expression of MMP1, MMP3, and TIMP1. The study ...
KEY FINDING: MMP1 and MMP3 expression increased significantly in experimental groups compared to controls. The increase correlated with longer exposure to simulated overload and microgravity.
J. Clin. Med., 2025 • January 9, 2025
Posterior vertebral resection techniques offer significant promise in the correction of pediatric spinal deformities. Careful case-by-case evaluation is necessary, especially because of the associated...
KEY FINDING: PVCR resulted in an average reduction in the Cobb angle from 86.3◦ preoperatively to 22.4◦ postoperatively, with a mean correction of 64%.
Journal of Orthopaedic Case Reports, 2025 • February 1, 2025
Spinal cord injury (SCI) is most common following trauma, typically involving motor vehicle incidents. The clinical prognosis depends on many factors, most importantly the initial grade of injury. We ...
KEY FINDING: A computed tomography scan demonstrated cervicomedullary transection caused by C6-C7 facet distraction with C6 retrolisthesis on C7.
Journal of Orthopaedic Surgery and Research, 2025 • February 10, 2025
This study retrospectively analyzed 22 patients with severe post-tubercular kyphosis (PTK) who underwent modified posterior vertebral column resection (mPVCR). The results demonstrated significant imp...
KEY FINDING: The modified PVCR technique resulted in a significant improvement in kyphosis angle (KA) from 129.5° to 43.7° postoperatively.
JMIR Formative Research, 2025 • February 24, 2025
This study evaluated the effectiveness of financial support workshops for patients with DCM under state pension age in the UK. The workshops, focusing on UC and PIP, were delivered in partnership with...
KEY FINDING: Participants rated the usefulness of the UC and PIP sessions highly, with average ratings of 9.00/10 and 10/10, respectively.
Fluids and Barriers of the CNS, 2025 • February 10, 2025
This study investigates the role of ependymal cilia and AQP4 in syringomyelia using a rat model. The findings highlight the significance of cilia on ependymal cells and the evolving microenvironment p...
KEY FINDING: Ependymal cilia are significantly reduced in syringomyelia, with altered morphology, and cell junctions between ependymal cells are loose and broken.
Cureus, 2025 • March 9, 2025
This case report describes a 72-year-old male who developed white cord syndrome (WCS) after undergoing posterior cervical laminectomy and fusion for cervical stenosis due to ossification of the poster...
KEY FINDING: The patient developed WCS after posterior cervical decompression and fusion for cervical stenosis caused by ossification of the posterior longitudinal ligament (OPLL).
Orthopaedic Surgery, 2022 • October 1, 2022
This study evaluated the effectiveness of single-door laminoplasty combined with atlantoaxial fusion for treating symptomatic atlas canal stenosis (SACS). The results showed significant improvements i...
KEY FINDING: Single-door laminoplasty combined with atlantoaxial fusion significantly increased the inner sagittal diameter of C1 and the space available for the spinal cord.
Medicine, 2022 • August 26, 2022
This retrospective study compared MRI features of SCI and CCM patients with intramedullary high-intensity lesions. The study measured lesion length, assessed snake-eye appearance, and calculated contr...
KEY FINDING: The longitudinal length of T2 high-intensity lesions was significantly longer in SCI patients than in CCM patients.
Frontiers in Neurology, 2024 • June 24, 2024
This cross-sectional study aimed to determine the significance of cardiac-related spinal cord motion and spinal stenosis as indicators of mechanical strain in degenerative cervical myelopathy (DCM) pa...
KEY FINDING: Patients with and without visible spinal cord damage on MRI (MRI+ and MRI-) showed similar levels of increased spinal cord motion and compression.