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Research Methodology & Design Research

Browse the latest research summaries in the field of research methodology & design for spinal cord injury patients and caregivers.

Showing 451-460 of 702 results

Spinal Cord InjuryNeurologyResearch Methodology & Design

A Model of Glial Scarring Analogous to the Environment of a Traumatically Injured Spinal Cord Using Kainate

Ann Rehabil Med, 2016 • October 1, 2016

This study developed an in vitro model of glial scarring that mimics the environment of a traumatically injured spinal cord using a combination of mechanical (scratch) and chemical (kainate) injuries....

KEY FINDING: Combining scratch injury with kainate treatment resulted in the most significant glial scarring, indicated by increased expression of GFAP, vimentin, CSPG, ROCK, and EphA4.

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Spinal Cord InjuryOrthopedicsResearch Methodology & Design

Checkpoints to Progression: Qualitative Analysis of the Personal and Contextual Factors that Influence Selection of Upper Extremity Reconstruction among Patients with Tetraplegia

J Hand Surg Am, 2017 • July 1, 2017

The study built a conceptual model outlining how personal and contextual factors influence patients' decisions regarding UER. Moving from functional dissatisfaction to awareness of UER was a major hur...

KEY FINDING: Patients who undergo UER typically progress through stages of functional dissatisfaction, awareness of UER, and acceptance of surgery.

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Spinal Cord InjuryRehabilitationResearch Methodology & Design

Understanding physical activity participation in spinal cord injured populations: Three narrative types for consideration

International Journal of Qualitative Studies on Health and Well-being, 2015 • August 14, 2015

This study used a narrative approach to understand physical activity participation in the spinal cord injured population, identifying three narrative types: exercise is restitution, exercise is medici...

KEY FINDING: The study identified three narrative types: (1) exercise is restitution, (2) exercise is medicine, and (3) exercise is progressive redemption.

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Spinal Cord InjuryNeurologyResearch Methodology & Design

Pronounced species divergence in corticospinal tract reorganization and functional recovery after lateralized spinal cord injury favors primates

Sci Transl Med, 2015 • August 26, 2015

The study investigated inter-species differences in recovery after lateralized spinal cord injury (SCI), focusing on the corticospinal tract reorganization. The researchers found that functional recov...

KEY FINDING: Functional gains increased with the laterality of spinal cord damage in humans.

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NeurologyTraumaResearch Methodology & Design

Paraplegia caused by cerebral contusions in the bilateral precentral gyri

Surgical Neurology International, 2016 • November 9, 2016

This case report describes a 72-year-old man who developed paraplegia due to cerebral contusions in the bilateral precentral gyri following a head injury. Initial CT and MRI scans of the spine were un...

KEY FINDING: Cerebral contusions in the bilateral precentral gyri can cause pure motor paraplegia.

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Spinal Cord InjuryAgingResearch Methodology & Design

SCI Longitudinal Aging Study: 40 Years of Research

Top Spinal Cord Inj Rehabil, 2015 • July 1, 2015

The SCI Longitudinal Aging Study, initiated in 1973, is a 40-year study examining the life situation of individuals with SCI, with a focus on aging. Five participant samples have been incorporated ove...

KEY FINDING: A 'survivor effect' exists, where individuals with SCI who are more active, well-adjusted, and healthier tend to live longer. This underscores the importance of psychosocial and vocational factors in longevity.

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Spinal Cord InjuryAssistive TechnologyResearch Methodology & Design

Letter to the editor regarding “Clinical effectiveness and safety of powered exoskeleton-assisted walking in patients with spinal cord injury: systematic review with meta-analysis”

Medical Devices: Evidence and Research, 2016 • November 29, 2016

Dijkers et al raise concerns about potential duplicate data in a meta-analysis regarding the clinical effectiveness and safety of powered exoskeletons for spinal cord injury (SCI) patients. They highl...

KEY FINDING: The letter identifies potential duplicate patient data in the meta-analysis by Miller et al.

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Spinal Cord InjuryPain ManagementResearch Methodology & Design

Standardizing the evaluation and management of neuropathic pain following spinal cord injury

CMAJ, 2017 • January 16, 2017

Neuropathic pain is a frequent complication of spinal cord injury that can significantly impair a patient's quality of life and ability to participate in daily activities. The CanPain SCI clinical pra...

KEY FINDING: The CanPain SCI clinical practice guideline is a valuable resource for clinicians treating neuropathic pain in patients after spinal cord injury.

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Spinal Cord InjuryNeurologyResearch Methodology & Design

A Systematic Review of Experimental Strategies Aimed at Improving Motor Function after Acute and Chronic Spinal Cord Injury

JOURNAL OF NEUROTRAUMA, 2016 • March 1, 2016

This systematic review evaluated various strategies for improving motor function after spinal cord injury (SCI), including single-intervention and multi-intervention approaches. The review found that ...

KEY FINDING: The highest level of evidence supports multi-intervention approaches that include a rehabilitation component for improving motor function after SCI.

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Spinal Cord InjuryResearch Methodology & DesignPublic Health

Measurement properties of a modified measure of participation for persons with spinal cord injury

The Journal of Spinal Cord Medicine, 2016 • July 1, 2016

This study aimed to refine a measure of participation (PM-PAC) for adults with spinal cord injury (SCI) based on a conceptual model of participation. The study involved secondary analysis of data from...

KEY FINDING: Three participation domains (Productivity, Social, and Community) were supported with good model fit in confirmatory factor analysis and good item fit in Rasch analysis.

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