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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Research Methodology & Design Research

Browse the latest research summaries in the field of research methodology & design for spinal cord injury patients and caregivers.

Showing 461-470 of 702 results

Spinal Cord InjuryNeurologyResearch Methodology & Design

Cough-induced hemiparesis: an unusual manifestation of cord compression

BMJ Case Rep, 2016 • May 12, 2016

This case report describes a 67-year-old woman with recurrent episodes of cough-induced hemiparesis due to atlantoaxial instability and spinal cord compression. The patient's symptoms were triggered b...

KEY FINDING: Atlantoaxial instability can cause spinal cord compression, leading to transient neurological symptoms.

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UrologyNeurologyResearch Methodology & Design

Successful bilateral pudendal neuromodulation to treat male detrusor areflexia following severe pubic symphysis fracture, a case report

BMC Urology, 2015 • October 29, 2015

This case report presents a successful instance of bilateral pudendal neuromodulation used to treat detrusor areflexia in a male patient following a severe pelvic fracture and subsequent complications...

KEY FINDING: Sacral neuromodulation can be effective in correcting traumatic urinary retention in male patients.

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AgingRehabilitationResearch Methodology & Design

Understanding non-performance reports for instrumental activity of daily living items in population analyses: a cross sectional study

BMC Geriatrics, 2016 • February 26, 2016

This study evaluated different strategies for classifying “does not do” responses to IADL questions when estimating prevalence of IADL limitations in a national survey. IADL stage prevalence estimates...

KEY FINDING: IADL stage prevalence estimates differed little across the four alternative strategies.

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Spinal Cord InjuryUrologyResearch Methodology & Design

Ureteral Rupture Caused by a Suprapubic Catheter in a Male Patient With Spinal Cord Injury: A Case Report

Ann Rehabil Med, 2016 • December 1, 2016

This case report describes a rare instance of ureteral rupture in a male patient with a spinal cord injury, caused by a suprapubic catheter. The patient developed complications 11 years after the init...

KEY FINDING: A 63-year-old male with SCI developed a ureteral rupture due to a suprapubic catheter 11 years after the initial injury.

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Spinal Cord InjuryTraumaResearch Methodology & Design

Disaster anxiety and self-assistance behaviours among persons with cervical cord injury in Japan: a qualitative study

BMJ Open, 2016 • April 1, 2016

This qualitative study investigated disaster-related anxiety and self-assistance behaviors among individuals with cervical cord injury (CCI) in Japan. The study found that participants were primarily ...

KEY FINDING: Participants primarily worried about managing their health, specifically urinary and fecal control, pressure sores, and body temperature, in a disaster scenario.

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Spinal Cord InjuryNeurologyResearch Methodology & Design

Brown-Sequard Syndrome after an Accidental Stab Injury of Cervical Spine: A Case Report

Korean J Neurotrauma, 2015 • June 1, 2015

This case report details a 42-year-old woman who developed Brown-Sequard syndrome (BSS) following an accidental stab wound to the cervical spine. The patient exhibited classic BSS symptoms, including ...

KEY FINDING: The patient presented with right-side hemiparesis, ipsilateral hypoesthesia, and contralateral sensory loss of pain and temperature, consistent with BSS.

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Spinal Cord InjuryRegenerative MedicineResearch Methodology & Design

Olfactory Ensheathing Cell Transplantation in Experimental Spinal Cord Injury: Effect size and Reporting Bias of 62 Experimental Treatments: A Systematic Review and Meta-Analysis

PLoS Biology, 2016 • May 31, 2016

This meta-analysis examined the efficacy of olfactory ensheathing cell (OEC) transplantation in experimental spinal cord injury (SCI). The study found a significant overall effect of OEC transplantati...

KEY FINDING: OEC transplantation improved locomotor recovery by 20.3% in experiments reporting BBB measures.

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Spinal Cord InjuryNeurologyResearch Methodology & Design

The swimming test is effective for evaluating spasticity after contusive spinal cord injury

PLoS ONE, 2017 • February 9, 2017

This study investigated the feasibility of using the swimming test to evaluate spasticity in a contusive spinal cord injury (SCI) rat model. Rats were divided into spasticity-strong and spasticity-wea...

KEY FINDING: The spasticity-strong group had significantly decreased rate-dependent depression of the H-reflex compared to the spasticity-weak group, indicating more hyperexcitability of the lumbar circuit.

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Spinal Cord InjuryUrologyResearch Methodology & Design

Prediction of Bladder Outcomes after Traumatic Spinal Cord Injury: A Longitudinal Cohort Study

PLoS Medicine, 2016 • June 21, 2016

The study developed and validated two models to predict urinary continence and complete bladder emptying 1 year after traumatic SCI using data from a large European multicenter study. The models, one ...

KEY FINDING: Two prediction models were developed: a full model using LEMS, light-touch sensation in the S3 dermatome, and SCIM subscale respiration and sphincter management; and a simplified model based on LEMS only.

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Spinal Cord InjuryRegenerative MedicineResearch Methodology & Design

Preclinical Efficacy Failure of Human CNS-Derived Stem Cells for Use in the Pathway Study of Cervical Spinal Cord Injury

Stem Cell Reports, 2017 • February 14, 2017

This study evaluated the efficacy of human neural stem cells (HuCNS-SCs) in a mouse model of cervical spinal cord injury (SCI), comparing a research cell line (RCL) and a clinical cell line (CCL) inte...

KEY FINDING: The research cell line (HuCNS-SC RCL) showed some improvement in locomotor function when transplanted 9 days post-injury (DPI) in mice with cervical SCI.

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