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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Research Methodology & Design Research

Browse the latest research summaries in the field of research methodology & design for spinal cord injury patients and caregivers.

Showing 281-290 of 702 results

Mental HealthNeurorehabilitationResearch Methodology & Design

Grieving a disrupted biography: an interpretative phenomenological analysis exploring barriers to the use of mindfulness after neurological injury or impairment

BMC Psychol, 2021 • August 11, 2021

The study explored the role of mindfulness in managing symptoms associated with sensory loss, focusing on experienced mindfulness practitioners with neurological disorders. Two superordinate themes we...

KEY FINDING: Mindfulness supports health self-management after neurological injury, but meditation can initially reactivate trauma and grief.

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Mental HealthNeurologyResearch Methodology & Design

A prospective examination of sex differences in posttraumatic autonomic functioning

Neurobiology of Stress, 2021 • August 21, 2021

This prospective study examined sex differences in autonomic functioning among individuals recently exposed to trauma. Participants were recruited from emergency departments and assessed for skin cond...

KEY FINDING: Men demonstrated significantly higher systolic blood pressure compared to women two weeks after trauma exposure.

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OncologyResearch Methodology & Design

Recent advances and new discoveries in the pipeline of the treatment of primary spinal tumors and spinal metastases: a scoping review of registered clinical studies from 2000 to 2020

Neuro-Oncology, 2022 • January 1, 2022

This scoping review highlights the key features of 174 clinical studies on spinal neoplasms registered from 2000 to 2020. Clinical trials are more focused on metastatic tumors than primary tumors, ref...

KEY FINDING: Most registered clinical studies were interventional and led by single institutions, mainly in North America and Europe.

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Medical ImagingResearch Methodology & Design

Author Correction: Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers

Scientific Data, 2021 • August 16, 2021

This is an author correction to a previously published Data Descriptor regarding open-access quantitative MRI data of the spinal cord. The correction addresses an error in the legend of Figure 16, whi...

KEY FINDING: The original figure legend incorrectly described the data presented in Figure 16.

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Spinal Cord InjuryRegenerative MedicineResearch Methodology & Design

Time-to-enrollment in clinical trials investigating neurological recovery in chronic spinal cord injury: observations from a systematic review and ClinicalTrials.gov database

Neural Regeneration Research, 2022 • September 17, 2021

This study aimed to evaluate the impact of time-to-enrollment in chronic SCI clinical trials by analyzing data from ClinicalTrials.gov and individual patient data from regenerative intervention trials...

KEY FINDING: The majority of chronic SCI trials in ClinicalTrials.gov do not restrict the maximum post-injury time for trial eligibility.

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Spinal Cord InjuryRehabilitationResearch Methodology & Design

Walking Ability Outcome Measures in Individuals with Spinal Cord Injury: A Systematic Review

International Journal of Environmental Research and Public Health, 2021 • September 9, 2021

This systematic review provides an updated qualitative review of walking ability outcome measures in SCI, considering diverse factors involving walking function and their limitations. Thirteen walking...

KEY FINDING: Thirteen different walking ability outcome measures were identified and grouped into categories, including multivariate walking metrics, spatiotemporal-related walking/balance measures, categorical measures of ambulation and balance measures.

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Spinal Cord InjuryBioinformaticsResearch Methodology & Design

Peripheral white blood cell responses as emerging biomarkers for patient stratification and prognosis in acute spinal cord injury

Curr Opin Neurol, 2021 • December 1, 2021

We survey recent advances in methods and approaches that may allow for a more refined diagnosis and better prognostication after acute SCI, discuss how these may help deepen our understanding of SCI p...

KEY FINDING: Significantly elevated neutrophil numbers in the blood of patients with an acute traumatic SCI and the likelihood of little to no functional improvement at hospital discharge.

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Assistive TechnologyHealthcareResearch Methodology & Design

User-Centered Design and Development of the Modular TWIN Lower Limb Exoskeleton

Frontiers in Neurorobotics, 2021 • October 7, 2021

This paper introduces TWIN, a modular lower limb exoskeleton developed using a user-centered design approach. The design process involved patients, engineers, and clinicians to identify key requiremen...

KEY FINDING: The study found that a user-centered design approach, involving patients and clinicians, was effective in developing an exoskeleton that addresses user needs.

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Spinal Cord InjuryResearch Methodology & DesignMusculoskeletal Medicine

A multilevel noncontiguous spinal fracture with cervical and thoracic spinal cord injury

International Journal of Surgery Case Reports, 2021 • October 19, 2021

This case report describes the operative management of an 18-year-old male with a multilevel noncontiguous spinal fracture (MNSF) and spinal cord injury involving the cervical and thoracic vertebrae. ...

KEY FINDING: MNSF with spinal cord injury following high-velocity accidents are unstable and complex injuries.

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Spinal Cord InjuryRehabilitationResearch Methodology & Design

Spinal Cord Injury – Functional Index/Capacity (SCI-FI/C): Responsiveness to Change over Time

Arch Phys Med Rehabil, 2022 • February 1, 2022

This study evaluated the responsiveness of the SCI-FI/C Basic Mobility, Self-Care, and Fine Motor item banks in individuals with SCI during the first year post-injury. Responsiveness was examined by c...

KEY FINDING: The SCI-FI Basic Mobility/C and Self-Care/C item banks demonstrated sensitivity to change at both 6 months and 1 year post-injury for individuals with SCI.

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