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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Rehabilitation Research

Browse the latest research summaries in the field of rehabilitation for spinal cord injury patients and caregivers.

Showing 41-50 of 3,020 results

Spinal Cord InjuryRehabilitationMusculoskeletal Medicine

Heterotopic ossification after spinal cord injury: prevention and treatment – a sistematic review

Acta Ortop Bras, 2023 • January 1, 2023

This systematic review investigates methods to prevent and treat neurogenic HO in people with spinal cord injuries, analyzing retrospective studies ranging from level 3 to 4 of evidence. Resection sur...

KEY FINDING: Non-steroidal anti-inflammatory drugs (NSAIDs) are the best method for preventing heterotopic ossification if administered in the acute period after spinal cord injury.

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Spinal Cord InjuryPain ManagementRehabilitation

Photobiomodulation reduces neuropathic pain after spinal cord injury by downregulating CXCL10 expression

CNS Neurosci Ther, 2023 • January 19, 2023

This study demonstrates that photobiomodulation (PBM) can alleviate neuropathic pain (NP) after spinal cord injury (SCI) in rats. PBM treatment led to improvements in pain-related behaviors and promot...

KEY FINDING: PBM therapy improves neuropathic pain behaviors after spinal cord injury in rats.

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Spinal Cord InjuryImmunologyRehabilitation

Photobiomodulation inhibits the expression of chondroitin sulfate proteoglycans after spinal cord injury via the Sox9 pathway

Neural Regeneration Research, 2024 • January 1, 2024

This study investigates the inhibitory effects of photobiomodulation (PBM) on the accumulation of chondroitin sulfate proteoglycans (CSPGs) after spinal cord injury (SCI). The findings demonstrate tha...

KEY FINDING: PBM irradiation markedly increased Basso Mouse Scale scores in SCI model mice from day 7 post-injury, and this difference was maintained until day 28.

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EndocrinologyNeurologyRehabilitation

Musculoskeletal and body composition response to high-dose testosterone with finasteride after chronic incomplete spinal cord injury—a randomized, double-blind, and placebo-controlled pilot study

Frontiers in Neurology, 2024 • December 11, 2024

This pilot study provides proof-of-concept for the use of TRT + finasteride in men with SCI. The treatment showed promise in improving body composition and musculoskeletal health. The results suggest ...

KEY FINDING: TRT + finasteride consistently increased testosterone and estradiol, while concomitantly reducing dihydrotestosterone.

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Spinal Cord InjuryNeurologyRehabilitation

Effects of exercise training on neurological recovery, TGF-β1, HIF-1α, and Nogo-NgR signaling pathways after spinal cord injury in rats

Clinics, 2023 • January 1, 2023

This study evaluated the effects of exercise training on neurological recovery after spinal cord injury (SCI) in rats, focusing on TGF-β1, HIF-1α, and Nogo-NgR signaling pathways. The results showed t...

KEY FINDING: Exercise training improved motor function in rats with spinal cord injury, as evidenced by increased BBB scores, modified Tarlow scores, and angles on the inclined plate.

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Assistive TechnologyRehabilitationBiomedical

Real-Life Wheelchair Mobility Metrics from IMUs

Sensors, 2023 • August 14, 2023

This study describes and validates a methodology to derive clinically relevant wheelchair mobility metrics (WCMMs) from IMUs placed on the wheelchair frame and wheel in real-life settings. The set of ...

KEY FINDING: IMUs can accurately measure wheelchair distance, speed, number of pushes, and turning characteristics in real-world settings.

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Spinal Cord InjuryRehabilitation

The effect of robot-assisted gait training for patients with spinal cord injury: a systematic review and meta-analysis

Frontiers in Neuroscience, 2023 • August 22, 2023

This meta-analysis evaluated 11 studies and found that robot-assisted gait training might improve TUG for spinal cord injury patients. The study indicates that robot-assisted training may not signific...

KEY FINDING: Robot-assisted gait training seems to be helpful for patients with spinal cord injuries to improve TUG (Timed Up and Go test results).

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Spinal Cord InjuryNursingRehabilitation

Application of nursing intervention based on Snyder’s hope theory in individuals with spinal cord injury

Am J Transl Res, 2024 • April 30, 2024

The study aimed to assess the effectiveness of nursing intervention based on Snyder’s hope theory in patients with spinal cord injury (SCI). The results indicated that the intervention significantly r...

KEY FINDING: Nursing intervention based on Snyder’s hope theory decreased anxiety and depression scores compared to routine care.

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NeurologyRehabilitation

Intermittent hypoxia-induced enhancements in corticospinal excitability predict gains in motor learning and metabolic e¨ciency

University of Colorado Boulder, 2024 • April 24, 2024

The study demonstrates that repetitive AIH amplifies excitability in lower limbs and improves motor learning and motor savings. Enhanced excitability is associated with greater metabolic efficiency, s...

KEY FINDING: AIH increases lower limb excitability, as evidenced by significant enhancements in MEPmax and the area under the recruitment curve.

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Spinal Cord InjuryPain ManagementRehabilitation

The Role of Exercise in the Alleviation of Neuropathic Pain Following Traumatic Spinal Cord Injuries: A Systematic Review and Meta-analysis

Neurospine, 2023 • September 1, 2023

This systematic review and meta-analysis aimed to assess the efficacy of exercise in neuropathic pain following traumatic spinal cord injuries. The meta-analysis of preclinical studies demonstrated th...

KEY FINDING: Exercise significantly improves mechanical allodynia, thermal hyperalgesia, and cold allodynia in rodent models of SCI.

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