Browse the latest research summaries in the field of physiology for spinal cord injury patients and caregivers.
Showing 251-260 of 321 results
The Journal of Physiology, 2018 • January 1, 2018
Spinal cord injury (SCI) in the cervical region increases the risk of obstructive sleep apnea (OSA). A study comparing individuals with and without SCI found impaired genioglossus (GG) muscle reflexes...
KEY FINDING: Individuals with SCI and OSA show impaired reflex activation of the genioglossus (GG) muscle, which helps keep the airway open.
Frontiers in Physiology, 2018 • May 18, 2018
This study investigated the acute cardiovascular effects of lumbosacral spinal cord epidural stimulation (scES) configured to facilitate motor activity in persons with SCI. The results showed that scE...
KEY FINDING: Spinal cord stimulation increased arterial blood pressure in individuals with SCI-induced cardiovascular deficits.
The Journal of Spinal Cord Medicine, 2019 • September 1, 2019
This study examined the impact of hybrid stimulation patterns, which combine paired-pulse doublets with constant-frequency background stimulation, on muscle torque in both paralyzed and non-paralyzed ...
KEY FINDING: Stimulation trains with doublets at both the start and middle yielded the most consistent enhancement of torque.
PLoS ONE, 2018 • June 27, 2018
This study assessed the association between circulating adipo-myokines and lean mass in 205 men with chronic SCI, finding a significant positive association between lean mass and leptin, independent o...
KEY FINDING: There was a significant positive association between lean mass and leptin in men with SCI that was independent of fat.
Spinal Cord Series and Cases, 2018 • June 19, 2018
The study examined the impact of self-guided training for the HandbikeBattle on fitness and body composition in individuals with spinal cord injury (SCI). It aimed to determine if training led to chan...
KEY FINDING: Training for the HandbikeBattle led to significant improvements in peak power output (POpeak).
BJU Int, 2019 • March 1, 2019
This study demonstrates that electrophysiological properties of the LUT are progressively impaired depending on SCI intensity and that intravesical P2X2/3R inhibition can attenuate electrical activity...
KEY FINDING: Severe SCI increased bladder contraction frequency and reduced bladder pressure amplitude and intraluminal-pressure high-frequency oscillations (IPHFO).
Arch Phys Med Rehabil, 2019 • June 1, 2019
This study investigated glucose metabolism differences among women with paraplegic and tetraplegic spinal cord injury (SCI) compared to able-bodied (AB) women, adjusting for body composition differenc...
KEY FINDING: Women with tetraplegia had higher glucose, insulin, and C-peptide concentrations at minute 120 during the oral glucose tolerance test (OGTT) compared to women with paraplegia and able-bodied women, even after adjusting for total body lean mass and percentage fat mass.
Korean J Neurotrauma, 2018 • August 20, 2018
Spinal shock is characterized by a temporary loss of reflexes and muscle tone below the injury level, with its resolution marked by the return of reflex activity, transitioning to spasticity over time...
KEY FINDING: The traditional view that reflexes return in a caudo-rostral sequence (from the tail to the head) after spinal shock may not be accurate.
JOURNAL OF NEUROTRAUMA, 2019 • May 1, 2019
Herein, we describe the surgical and intraoperative electrophysiological approach used, followed by initial EES-enabled results observed in 2 human subjects with motor complete paralysis who were enro...
KEY FINDING: Positioning active electrodes at the rostral region of the array resulted in significantly higher EES-evoked motor response amplitudes in proximal leg muscles.
Respir Physiol Neurobiol, 2019 • March 1, 2019
This study examined the effects of cervical spinal cord contusion (C2SC) on NKCC1 and KCC2 expression in phrenic motor neurons of rats. The researchers found that 5 weeks post-C2SC, while individual e...
KEY FINDING: Membrane-bound NKCC1 expression was not significantly affected by C2SC, but the membrane/cytosolic ratio increased.