Browse the latest research summaries in the field of physiology for spinal cord injury patients and caregivers.
Showing 181-190 of 321 results
Exp Neurol, 2017 • January 1, 2017
The study demonstrates that daily acute intermittent hypoxia (dAIH) improves breathing capacity and diaphragm activity in rats with chronic cervical spinal injuries. Combining dAIH with A2A receptor i...
KEY FINDING: Daily AIH improves tidal volume (VT) and bilateral diaphragm activity in rats with chronic cervical spinal injuries.
Respir Physiol Neurobiol, 2016 • July 15, 2016
This study examined the effect of Parkinson’s disease (PD) on pharyngeal somato-sensation using the PSEP protocol. The PD participants had a significant decrease in the N2 latency compared to the HOA....
KEY FINDING: PD participants had a decreased N2 latency, indicating faster processing of the stimulus.
The Journal of Spinal Cord Medicine, 2016 • January 1, 2016
This case report investigated the effect of acute intermittent hypoxia (AIH) treatment on ventilatory load compensation and respiratory perceptual sensitivity to inspiratory resistive loads (IRL) in a...
KEY FINDING: Significant improvements in airflow generated in response to applied inspiratory resistive loads were found after AIH treatment compared to Baseline.
Clin J Pain, 2015 • October 1, 2015
This study investigates the relationship between anterior brain asymmetry (FAA) and future pain-related catastrophizing in individuals with spinal cord injury. The AAE model suggests that greater left...
KEY FINDING: Anterior asymmetry scores reflecting greater left than right anterior activity were negatively associated with subsequent catastrophizing.
Respir Physiol Neurobiol, 2016 • October 1, 2016
The study investigates the potential of high-frequency spinal cord stimulation (HF-SCS) to restore cough function in individuals with neuromuscular diseases, addressing the limitations of conventional...
KEY FINDING: At any given level of stimulus current below 2mA, airway pressure generation was substantially larger at 500Hz compared to 50Hz.
The Journal of Neuroscience, 2016 • July 27, 2016
The study demonstrates that both moderate and severe hypoxia can induce phrenic motor facilitation (pMF) through competing serotonin- and adenosine-dependent mechanisms in the spinal cord. The specifi...
KEY FINDING: Blocking spinal A2A receptors with MSX-3 reveals mASH-induced pMF.
Exp Neurol, 2015 • January 1, 2015
The purpose of the present study was to define the capacity for a single bout of hypoxia to trigger short-term plasticity in phrenic output after cervical SCI, and to determine the phrenic motoneuron ...
KEY FINDING: A single bout of hypoxia triggers recruitment of PhrMNs in the ipsilateral spinal cord with bursting that persists beyond the hypoxic exposure.
Journal of Visualized Experiments, 2016 • July 29, 2016
This protocol describes a detailed implementation of a novel JAVA platform AD Detection software which would be combined with a telemetry device, for a long-term thorough analysis of ABP in SCI-animal...
KEY FINDING: The software characterizes spontaneous AD events by an increase in SBP greater than 20 mmHg accompanied by a decrease in HR of 40 bpm or greater.
The Journal of Spinal Cord Medicine, 2018 • January 1, 2018
This study investigated the impact of spinal cord injury (SCI) on auditory startle responses (ASR) and startle reflexes to somatosensory stimuli (SSS). The findings revealed that ASRs were enhanced in...
KEY FINDING: Patients with SCI exhibited exaggerated auditory startle responses (ASRs) compared to healthy controls.
The Journal of Spinal Cord Medicine, 2016 • January 1, 2016
The study investigated the effect of reducing NMES RT frequency to once weekly on body composition and knee extensor strength in a person with chronic complete SCI. Results showed that once weekly NME...
KEY FINDING: Once weekly NMES RT increased leg lean mass (LM) by >6%.