Browse the latest research summaries in the field of physiology for spinal cord injury patients and caregivers.
Showing 171-180 of 321 results
Frontiers in Physiology, 2018 • December 6, 2018
The study investigated the convergence of vestibulospinal and corticospinal pathways on lumbosacral motor pools in humans using transcutaneous electrical spinal stimulation, galvanic vestibular stimul...
KEY FINDING: Corticospinal volleys facilitate spinally evoked motor potentials at short latencies (10-30 ms).
Journal of Visualized Experiments, 2015 • September 23, 2015
This study presents an in vitro model using organotypic spinal cord co-cultures on MEAs to investigate functional regeneration after spinal cord injury. The model allows for the study of propriospinal...
KEY FINDING: Cultures lesioned at a young age (7 - 9 DIV) displayed a high amount of synchronized activity 2-3 weeks after lesion, indicating a greater capacity for regeneration.
Dev Biol, 2015 • December 1, 2015
This study investigates the response of ependymoglial cells to spinal cord injury in axolotls, focusing on the role of membrane potential dynamics in regeneration. The research demonstrates that spina...
KEY FINDING: Spinal cord injury induces a rapid and dynamic change in the resting membrane potential of ependymoglial cells in axolotls.
Neural Regen Res, 2021 • July 1, 2021
The study systematically analyzed clinical neurological functions, combined with examination of SEP and MEP, ranging from gross to fine motor skills in a rat model of SCI. Rats with severe SCI showed ...
KEY FINDING: Somatosensory and motor-evoked potential amplitudes decreased and latencies increased after spinal cord contusion injury.
Exp Neurol, 2021 • April 1, 2021
This study investigated serotonergic reinnervation of respiratory motor nuclei (phrenic and intercostal) following cervical spinal hemisection (C2Hx) in rats, and the impact of different intermittent ...
KEY FINDING: Spontaneous serotonergic reinnervation of the phrenic and intercostal motor nuclei is substantial 12 weeks post-C2Hx.
Muscle Nerve, 2014 • October 1, 2014
The study investigated the effects of neuromuscular electrical stimulation–induced resistance exercise (NMES-RE) on intracellular signaling pathways involved in translation initiation and mechanical l...
KEY FINDING: SCI muscle appears to be more sensitive to muscle contraction even several years after the injury, possibly due to heightened compensatory mechanisms against muscle atrophy.
Spinal Cord, 2016 • March 8, 2016
This study experimentally evaluated the effect of hypovolemia in acute traumatic spinal cord injury in rats. The study found that hypovolemia after traumatic spinal cord injury had a negative effect o...
KEY FINDING: Spinal cord contusion associated with hypovolemia had a negative influence on functional outcomes of the spinal cord injury.
The Journal of Spinal Cord Medicine, 2014 • January 1, 2014
This study investigated the effects of intermittent passive standing (PS) and whole body vibration (WBV) on muscle activity, cross-sectional area, and density of lower extremity muscles in individuals...
KEY FINDING: PS-WBV acutely induced EMG activity in lower extremity muscles of SCI subjects.
The Journal of Spinal Cord Medicine, 2016 • January 1, 2016
The study investigated the longitudinal effects of exercise cessation on body composition and metabolic profiles in men with chronic spinal cord injury (SCI). Following a 2.5-year washout period after...
KEY FINDING: Thigh circumference increased after exercise and remained greater than baseline, but leg lean mass increased following exercise and decreased in the follow-up visit.
The Journal of Spinal Cord Medicine, 2015 • January 1, 2015
This study examined the impact of chronic activity-based therapy (ABT) on body composition and metabolic markers in individuals with spinal cord injury (SCI). The results indicated that ABT did not si...
KEY FINDING: There was no significant change in body weight, percent body fat, or FFM of the leg, arm, or trunk across all subjects after 6 months of ABT.