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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Pain Management Research

Browse the latest research summaries in the field of pain management for spinal cord injury patients and caregivers.

Showing 551-560 of 682 results

Spinal Cord InjuryPharmacologyPain Management

Cannabis shenanigans: advocating for the restoration of an effective treatment of pain following spinal cord injury

Spinal Cord Series and Cases, 2018 • June 7, 2018

The author argues that cannabis is an effective pain reliever for individuals with spinal cord injuries and should be more accessible for both patients and researchers. The paper highlights the histor...

KEY FINDING: Patients with SCI and chronic pain report cannabis as the single most effective medication out of 26 pain treatments.

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Spinal Cord InjuryPharmacologyPain Management

The enigma of cannabis use in spinal cord injury

Spinal Cord Series and Cases, 2018 • May 26, 2018

Cannabis presents a complex challenge due to its intricate effects on the central nervous system. Practitioners hold differing opinions on cannabis, awaiting more definitive evidence regarding its the...

KEY FINDING: The composition of cannabis sativa is complex, consisting of hundreds of cannabinoids as well as terpenes, flavinoids, and phenoids.

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Spinal Cord InjuryNeurologyPain Management

Exercise-Induced Changes to the Macrophage Response in the Dorsal Root Ganglia Prevent Neuropathic Pain after Spinal Cord Injury

JOURNAL OF NEUROTRAUMA, 2019 • March 15, 2019

This study investigates the immunomodulatory effects of exercise on neuropathic pain development after spinal cord injury (SCI) in rats. The research reveals that rats with SCI-induced neuropathic pai...

KEY FINDING: Rats with SCI-induced neuropathic pain exhibited greater microglial activation in the dorsal horn compared to rats without pain. Exercise reduced this activation.

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Pain ManagementOrthopedicsPublic Health

Prevalence of Neck Pain among Athletes: A Systematic Review

Asian Spine J, 2018 • December 1, 2018

This systematic review aimed to determine the prevalence of neck pain (NP) among athletes by analyzing existing literature up to September 2015. The review included six studies with low-to-moderate ri...

KEY FINDING: The review found that neck pain is highly prevalent among athletes, similar to the general population.

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Spinal Cord InjuryNeurologyPain Management

Neuropathic pain modulation after spinal cord injury by breathing-controlled electrical stimulation (BreEStim) is associated with restoration of autonomic dysfunction

Journal of Pain Research, 2018 • January 1, 2018

This study explored the modulation of chronic neuropathic pain (NP) following spinal cord injury (SCI) using breathing-controlled electrical stimulation (BreEStim) and measured changes in heart rate v...

KEY FINDING: SCI+NP subjects had lower baseline HRV compared to SCI–NP subjects.

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Spinal Cord InjuryPain ManagementNutrition & Dietetics

Maintenance of diet participation in individuals with spinal cord injury: effect on mood and neuropathic pain

Spinal Cord Series and Cases, 2018 • October 16, 2018

This study followed up with individuals with SCI who had previously completed a 3-month anti-inflammatory diet to assess their dietary compliance and the persistence of benefits related to mood and ne...

KEY FINDING: Diet compliance significantly decreased from 92.6% at 3 months to 43.0% at the 1-year follow-up (p < 0.01).

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ImmunologyPain ManagementOrthopedics

Morphine Exacerbates Post-Fracture Nociceptive Sensitization, Functional Impairment, and Microglial Activation in Mice

Anesthesiology, 2019 • February 1, 2019

This study demonstrates that morphine administration following a tibial fracture in mice exacerbates nociceptive sensitization and functional impairment, prolonging recovery. The adverse effects of mo...

KEY FINDING: Morphine treatment after tibial fracture exacerbates mechanical nociceptive sensitization and prolongs its duration.

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Pain ManagementRehabilitationResearch Methodology & Design

Chronic Pain Rehabilitation for Upper Extremity Pain Following Stimulator Removal

Am J Case Rep, 2018 • November 19, 2018

This report is a single subject case study of a unique circumstance in which a patient was provided 2 treatment modalities in a manner creating a natural experimental design. Pain reduction was eviden...

KEY FINDING: Pain intensity decreased following SCS placement and CPRP.

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NeurologyPain ManagementGenetics

RNA-seq of spinal cord from nerve-injured rats after spinal cord stimulation

Molecular Pain, 2018 • November 12, 2018

This study used RNA-seq to identify gene expression changes in the spinal cord of nerve-injured rats after repetitive conventional spinal cord stimulation (SCS) treatment. The RNA-seq data suggest fur...

KEY FINDING: Repetitive SCS further increases many existing upregulated immune responses in chronic constrictive injury rats, including transcription of cell surface receptors and activation of non-neuronal cells.

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NeurologyPain Management

The impact of electrical charge delivery on inhibition of mechanical hypersensitivity in nerve-injured rats by sub-sensory threshold spinal cord stimulation

Neuromodulation, 2019 • February 1, 2019

The study aimed to determine whether sub-sensory threshold SCS of lower frequencies can also inhibit mechanical hypersensitivity in nerve-injured rats and examine how electric charge delivery of stimu...

KEY FINDING: Both high (10 kHz) and lower frequencies (200 Hz, 500 Hz, 1200 Hz) of subthreshold SCS attenuated mechanical hypersensitivity in nerve-injured rats.

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