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Pain Management Research

Browse the latest research summaries in the field of pain management for spinal cord injury patients and caregivers.

Showing 451-460 of 682 results

Spinal Cord InjuryAlternative MedicinePain Management

Auricular acupuncture for spinal cord injury related neuropathic pain: a pilot controlled clinical trial

The Journal of Spinal Cord Medicine, 2017 • July 1, 2017

This pilot study investigated the effects of Battlefield Acupuncture (BFA) on neuropathic pain in individuals with spinal cord injury (SCI). The study found that participants who received BFA reported...

KEY FINDING: The BFA group reported significantly more pain reduction than the delayed entry group (average change in NRS at eight weeks –2.92 ± 2.11 vs. −1.13 ± 2.14, P = 0.065).

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Spinal Cord InjuryParticipationPain Management

Changes in pain and quality of life in depressed individuals with spinal cord injury: does type of pain matter?

The Journal of Spinal Cord Medicine, 2016 • January 1, 2016

The study examined the relationship between neuropathic and nociceptive pain, pain interference, and quality of life (QoL) in individuals with spinal cord injury (SCI) participating in an antidepressa...

KEY FINDING: Lower baseline nociceptive pain interference was associated with higher satisfaction with life and mental health-related QoL at 12 weeks.

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Spinal Cord InjuryHealthcarePain Management

Health care utilization and expenditures among Medicaid beneficiaries with neuropathic pain following spinal cord injury

Journal of Pain Research, 2014 • July 1, 2014

The study evaluated health care resource utilization (HRU) and costs for neuropathic pain (NeP) secondary to spinal cord injury (SCI) among Medicaid beneficiaries. Significantly higher HRU and total c...

KEY FINDING: Patients with SCI-NeP had significantly higher percentages of physician office visits, emergency department visits, SCI- and pain-related procedures, and outpatient prescription utilization compared to the SCI-only cohort.

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PharmacologyNeurologyPain Management

An open-label, long-term study examining the safety and tolerability of pregabalin in Japanese patients with central neuropathic pain

Journal of Pain Research, 2014 • July 28, 2014

The study aimed to evaluate the long-term safety and tolerability of pregabalin in Japanese patients with central neuropathic pain over a 53-week period. The results indicated that pregabalin was gene...

KEY FINDING: A majority of patients (87.4%) experienced at least one treatment-related adverse event, most commonly somnolence, weight gain, dizziness, or peripheral edema.

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AnesthesiologyNeurologyPain Management

Differential Effects of Voltage-Gated Calcium Channel Blockers on Calcium Channel Alpha-2-Delta-1 Subunit Protein Mediated Nociception

Eur J Pain, 2015 • May 1, 2015

This study investigates the differential contributions of N-, L-, and P/Q-type voltage-gated calcium channels (VGCC) to behavioral hypersensitivity mediated by Cavα2δ1 dysregulation using a Cavα2δ1 ov...

KEY FINDING: N-type and L-type VGCC blockers (ω-conotoxin GVIA and nifedipine, respectively) significantly attenuated mechanical hypersensitivity in both the Cavα2δ1 overexpression (TG) and spinal nerve ligation (SNL) models.

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NeurologyPain ManagementMedical Imaging

Spinal Autofluorescent Flavoprotein Imaging in a Rat Model of Nerve Injury-Induced Pain and the Effect of Spinal Cord Stimulation

PLoS ONE, 2014 • October 3, 2014

This study uses Autofluorescent Flavoprotein Imaging (AFI) to examine changes in spinal dorsal horn metabolic activity in a rat model of nerve-injury induced pain (Seltzer model) and the effect of spi...

KEY FINDING: Neuropathic rats demonstrated an AFI-response to palpation, while naı¨ve rats did not.

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NeurologyPain Management

Baseline Brain Activity Predicts Response to Neuromodulatory Pain Treatment

Pain Med, 2014 • December 1, 2014

The study investigated whether baseline EEG-assessed brain oscillations predict response to neuromodulatory treatments for chronic pain in individuals with spinal cord injury. The key finding was that...

KEY FINDING: Higher presession theta activity was associated with greater pain reduction with hypnotic analgesia.

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Pain ManagementNutrition & DieteticsRehabilitation

Association Between Serum 25(OH)D Level and Nonspecific Musculoskeletal Pain in Acute Rehabilitation Unit Patients

JPEN J Parenter Enteral Nutr., 2016 • March 1, 2016

The study investigated the association between vitamin D status and nonspecific musculoskeletal pain in acute rehabilitation unit (ARU) patients. The results showed an inverse relationship between ser...

KEY FINDING: Serum 25(OH)D level was inversely associated with nonspecific musculoskeletal pain.

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Spinal Cord InjuryPharmacologyPain Management

An Exploratory Human Laboratory Experiment Evaluating Vaporized Cannabis in the Treatment of Neuropathic Pain from Spinal Cord Injury and Disease

J Pain, 2016 • September 1, 2016

This study investigated the analgesic efficacy of vaporized cannabis in patients with neuropathic pain related to spinal cord injury or disease. Participants underwent a randomized, double-blind, plac...

KEY FINDING: Vaporized cannabis provided significant pain relief compared to placebo in participants with neuropathic pain related to spinal cord injury or disease.

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Pain ManagementPediatricsDisability

DEFINING MILD, MODERATE, AND SEVERE PAIN IN YOUNG PEOPLE WITH PHYSICAL DISABILITIES

Disabil Rehabil., 2017 • June 1, 2017

This study aimed to identify appropriate cutoffs for classifying average and worst pain intensity in young people with physical disabilities. The results suggest that different cutoffs are needed for ...

KEY FINDING: The study found a non-linear association between pain intensity and pain interference.

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