Browse the latest research summaries in the field of pain management for spinal cord injury patients and caregivers.
Showing 431-440 of 682 results
Int. J. Environ. Res. Public Health, 2023 • December 21, 2022
This qualitative study explored the experiences and challenges of chronic pain management among individuals with traumatic spinal cord injury (TSCI) in the Western Cape, South Africa, revealing dissat...
KEY FINDING: Standard pain management, largely pharmacological, is often ineffective in providing significant or lasting relief for chronic pain in TSCI patients.
Spinal Cord Series and Cases, 2023 • January 1, 2023
This pilot study assessed the impact of a novel pain self-management program (PSMP) for persons living with chronic SCI pain, inspired by previously conducted programs, but with a specific focus on in...
KEY FINDING: For five out of the six participants, a majority of outcomes improved during either of the intervention phases or both.
Indian J Otolaryngol Head Neck Surg, 2022 • August 3, 2021
The study investigated SCM-VEMP and SETMP responses in patients with CMPS-D compared to a control group to assess saccular function and the etiology of dizziness. SCM-VEMP amplitudes were significantl...
KEY FINDING: The SCMVEMP response was absent in 4 of 15 patients with CMPS-D, and the mean response in the CMPS-D group was significantly lower than the control group.
Molecular Pain, 2023 • January 1, 2023
The study demonstrated that NKCC1 is overexpressed in the spinal cord and DRGs in a rat model of neuropathic pain following spinal cord injury. Inhibition of NKCC1 with bumetanide reduced mechanical e...
KEY FINDING: NKCC1 protein expression was significantly upregulated in the spinal cord and DRGs of rats with SCI.
BMC Musculoskeletal Disorders, 2023 • February 15, 2023
This study explored the pain-inhibitory effects of neuromuscular electrical stimulation (NMES) compared to volitional contractions and noxious electrical stimulation (NxES) in healthy participants. Th...
KEY FINDING: Noxious electrical stimulation (NxES) produced higher pain ratings compared to neuromuscular electrical stimulation (NMES).
Life, 2023 • January 17, 2023
This review provides an up-to-date overview of rTMS for treating neuropathic pain, summarizing treatment protocols and adverse effects from existing clinical trials. Current evidence suggests that 10 ...
KEY FINDING: Current evidence supports the use of 10 Hz HF-rTMS of the primary motor cortex to reduce neuropathic pain.
Frontiers in Molecular Neuroscience, 2023 • February 16, 2023
This study investigated the analgesic effect of Resveratrol (Res) in a rat model of spinal cord injury (SCI), focusing on its impact on neuropathic pain (NP) and underlying mechanisms. The findings in...
KEY FINDING: Intrathecal administration of Resveratrol (Res) alleviated mechanical allodynia in rats with spinal cord injury (SCI) for up to 21 days.
Frontiers in Molecular Neuroscience, 2023 • March 3, 2023
This study investigates the mechanisms behind neuropathic pain (NP) induced by spinal cord injury (SCI) in mice, focusing on the role of Nav1.7, a voltage-gated sodium channel. The findings demonstrat...
KEY FINDING: SCI induces ectopic expression of Nav1.7 in SDH neurons, making them hypersensitive and contributing to central sensitization and spontaneous/walking-evoked mechanical pain.
Frontiers in Pain Research, 2023 • March 9, 2023
This review examines various neuromodulation modalities for managing pain and restoring function in SCI patients, highlighting the potential of HF-SCS and B-SCS for pain relief. DRG-S and TMS show pro...
KEY FINDING: High-frequency spinal cord stimulation (HF-SCS) and burst spinal cord stimulation (B-SCS) have been shown to have the most promising effect in improving pain intensity and frequency.
NeuroImage: Clinical, 2023 • April 20, 2023
This study examined resting-state functional connectivity (rsFC) in individuals with spinal cord injury (SCI) to differentiate between neuropathic and nociceptive pain. The researchers aimed to identi...
KEY FINDING: Higher neuropathic pain severity was significantly associated with lower connectivity between the right posterior parahippocampal gyrus (pPaHC) to the right putamen and amygdala.