Browse the latest research summaries in the field of pain management for spinal cord injury patients and caregivers.
Showing 361-370 of 682 results
Front. Cell. Neurosci., 2019 • November 21, 2019
The study investigated the role of CCL21 in neuropathic pain (NeP) after spinal cord injury (SCI) using CCL21 knockout (plt) mice. plt mice exhibited reduced mechanical and thermal hypersensitivity af...
KEY FINDING: SCI-induced hypersensitivities to mechanical and thermal stimulation were relieved in plt mice compared with wild-type mice.
JOURNAL OF NEUROTRAUMA, 2020 • August 1, 2020
This study investigated the effects of FTY720 on neuropathic pain in a rat model of spinal cord injury (SCI). FTY720, a sphingosine-1-phosphate receptor agonist, was administered to female rats 24 hou...
KEY FINDING: FTY720 significantly attenuated post-traumatic neuropathic pain in a rat model of spinal cord injury.
Medicine, 2019 • December 6, 2019
This case report describes a 50-year-old woman who developed acute cervical myelopathy with quadriparesis following a cervical TFESI. MRI revealed spinal cord damage, and the patient was treated with ...
KEY FINDING: Cervical TFESI can lead to spinal cord injury despite careful fluoroscopic guidance.
Physiological Reports, 2019 • January 1, 2019
This study demonstrates that dendritic spine dysgenesis occurs in ventral horn motor neurons following burn injury, suggesting motor neuron synaptic plasticity. Romidepsin, a Pak1-inhibitor, restored ...
KEY FINDING: Second-degree burn injury significantly affects motor neuron structure within the spinal cord, specifically increasing dendritic spine density.
Journal of International Medical Research, 2019 • April 1, 2019
The study aimed to determine the role of spinal adenosine A1 receptors (A1Rs) in the analgesic effects of electroacupuncture (EA) for neuropathic pain using a rat model. Results showed that EA increas...
KEY FINDING: Electroacupuncture (EA) at the zusanli acupoint increases adenosine levels in the L4–6 spinal cord of rats.
Chinese Medical Journal, 2020 • January 1, 2020
This study investigated the effect of pulsed radiofrequency (PRF) on neuropathic pain (NP) in a rat model of chronic constriction injury (CCI). The findings suggest that PRF alleviates CCI-induced NP ...
KEY FINDING: PRF treatment significantly increased hindpaw withdrawal threshold (HWT) and thermal withdrawal latency (TWL) in CCI model rats after 28 days.
Journal of Exercise Rehabilitation, 2019 • December 1, 2019
This study aimed to determine the most effective core stability exercise position and technique (drawing-in vs. bracing) for activating the transverse abdominis (TrA) muscle. We aimed to compare the a...
KEY FINDING: Abdominal bracing in the bridge position resulted in the highest activation of the transverse abdominis muscle compared to other positions and the drawing-in technique. AB in the bridge position showed the highest activation of TrA.
Nutrients, 2020 • January 3, 2020
The study investigates the antinociceptive and anti-inflammatory effects of Nypa fruticans Wurmb extracts (NFE) in a rat model of sciatic nerve crush injury, focusing on the role of TRPV1. Results ind...
KEY FINDING: NFE (500 mg/kg) significantly delayed paw withdraw reaction in thermal hyperalgesia test compared to the vehicle group.
Journal of Clinical Medicine, 2020 • January 5, 2020
This study assessed the perceived helpfulness of various treatment modalities within a multidisciplinary pain management program (MPMP) for chronic back pain (CBP) patients. The study found that patie...
KEY FINDING: Patients' perceived treatment helpfulness differs significantly between treatment modalities, with individual physiotherapy being rated the highest and music therapy the lowest.
Frontiers in Human Neuroscience, 2020 • January 10, 2020
The study investigated contact heat stimulation parameters to detect peripheral sensitization related to topical capsaicin application, aiming to improve CHEP-based measurement of sensitization. Resul...
KEY FINDING: Capsaicin sensitization resulted in increased pain ratings in the primary area of hyperalgesia.