Browse the latest research summaries in the field of pain management for spinal cord injury patients and caregivers.
Showing 281-290 of 682 results
Orthopedic Reviews, 2024 • January 1, 2024
This review consolidates recent research on biologic complications associated with spinal cord stimulation (SCS), emphasizing the importance of understanding these risks for patient safety and optimal...
KEY FINDING: Infections are a potential complication, often caused by bacteria like streptococcus and staphylococcus, and may require device removal.
European Journal of Medical Research, 2024 • January 1, 2024
The study investigated the mechanism by which pulsed radiofrequency (PRF) alleviates neuropathic pain (NP) in a rat model of chronic constriction injury (CCI). PRF treatment was found to alleviate NP ...
KEY FINDING: PRF treatment alleviated NP in CCI rats, and upregulated the expression of MG53 while inhibiting microglial activation.
Interventional Pain Medicine, 2024 • November 25, 2024
This review summarizes the interventional pain management methods used for pediatric CRPS, noting the lack of high-quality evidence and specific protocols for diagnosis and management. Techniques like...
KEY FINDING: Interventional pain management methods like continuous epidural anesthesia, lumbar sympathetic blocks, and spinal cord stimulation have been used safely and successfully in treating pediatric CRPS as part of a multimodal strategy.
Cureus, 2024 • November 22, 2024
This systematic review assessed the efficacy of neuromodulation, interventional, and unconventional treatments for CRPS, focusing on pain reduction and secondary outcomes. The review identified 23 art...
KEY FINDING: Dorsal Root Ganglion (DRG) stimulation and Spinal Cord Stimulation (SCS) demonstrated statistically significant pain reduction.
Front. Neurosci., 2024 • December 11, 2024
This study investigates the analgesic effects of Dahuang Fuzi Decoction (DF) on neuropathic pain (NeP) using a rat model of chronic sciatic nerve compression injury (CCI). The research combines chemic...
KEY FINDING: DF treatment significantly increased the mechanical withdrawal threshold (MWT) and thermal withdrawal latency (TWL) in CCI rats, indicating its analgesic effect.
Frontiers in Neurology, 2024 • December 24, 2024
This study provides a bibliometric analysis of neuropathic pain (NP) research after spinal cord injury (SCI) from 2013 to 2024, using CiteSpace to analyze publications, journals, authors, references, ...
KEY FINDING: There was an overall upward trend in the number of publications on neuropathic pain after spinal cord injury between 2013 and 2024.
Cell & Bioscience, 2025 • January 2, 2025
This study investigates the role of AEA and its receptors, TRPV1 and CB1R, in the hyperexcitability of nociceptors after spinal cord injury (SCI). The key findings include that SCI increases AEA level...
KEY FINDING: SCI induces increased AEA content and hyperactivity in nociceptors, with the timing of SCI-induced hyperexcitability paralleling an increase in AEA content.
Archives of Rehabilitation Research and Clinical Translation, 2024 • January 1, 2024
This case report investigates the effectiveness of cryoneurolysis for pain and spasticity in a patient with spinal cord injury, severe orthopedic deformity, and impaired hand function. Percutaneous cr...
KEY FINDING: Cryoneurolysis led to immediate and sustained improvements in ROM in both upper and lower limbs.
Scientific Reports, 2025 • January 13, 2025
This study explores the protective effect of prior exercise against neuropathic pain (NP) in rats by examining protein expression changes in the spinal dorsal horn using proteomic analysis. The findin...
KEY FINDING: Prior exercise significantly increased the mechanical withdrawal threshold (MWT) and thermal withdrawal latency (TWL) in rats with CCI, indicating a reduction in pain sensitivity.
Journal of Medical Case Reports, 2025 • January 8, 2025
This case report describes the successful insertion of a new intrathecal baclofen catheter in a patient with a fractured catheter, without removing the original fractured catheter. The new catheter wa...
KEY FINDING: The intrathecal baclofen catheter breakage was identified as the cause of the patient's worsening spasticity 13 years after the initial pump implantation.