Browse the latest research summaries in the field of pain management for spinal cord injury patients and caregivers.
Showing 251-260 of 682 results
SAGE Open Medical Case Reports, 2024 • May 13, 2024
This case report presents the successful use of epidural steroid injection (ESI) to manage severe lower limb spasticity in a 33-year-old male with traumatic paraplegia following a knife assault. The p...
KEY FINDING: Epidural steroid injection led to a significant decrease in spasticity in a patient with traumatic paraplegic lumbar spinal cord injury.
J. Clin. Med., 2024 • May 23, 2024
This systematic review assessed the effectiveness of exercise interventions in alleviating upper body pain among spinal cord injury (SCI) patients. The results provide substantial evidence supporting ...
KEY FINDING: Exercise interventions are effective in reducing pain in patients with SCI, with a particular emphasis on alleviating shoulder pain.
Spinal Cord, 2024 • June 19, 2024
This study was a phase IIA clinical trial designed to assess the safety, tolerability, and preliminary efficacy of NFX88 in treating neuropathic pain in individuals with spinal cord injury. The trial ...
KEY FINDING: NFX88 treatment was found to be highly safe and well tolerated in individuals with spinal cord injury.
Ann Rehabil Med, 2024 • May 1, 2024
This systematic review and meta-analysis examined the effects of Botox-A on spasticity and nociceptive pain in individuals with spinal cord injuries (SCIs). The study included two randomized controlle...
KEY FINDING: Botox-A significantly decreased spasticity in SCI patients (SMD, -1.73; 95% CI, -2.51 to -0.95; p<0.0001, I2=48%).
Archives of Rehabilitation Research and Clinical Translation, 2024 • January 1, 2024
The study prospectively examined patients with prior chronic pain who suffered an acute complete spinal cord injury (SCI) to determine if the pre-existing pain persisted, changed, and whether opioids ...
KEY FINDING: Four out of seven participants with prior chronic pain continued to experience the same pain after complete tetraplegia.
Cureus, 2024 • June 22, 2024
This study aimed to determine the efficacy of minimal exercise intervention in relieving neuropathic pain in a rat model. Rats with chronic constriction injury (CCI) were divided into exercise and non...
KEY FINDING: Rats in the exercise group showed a significantly higher pain threshold compared to the non-exercise group five weeks after nerve injury, indicating pain relief.
Spinal Cord Series and Cases, 2024 • July 23, 2024
This feasibility study investigated the use of virtual walking (VW) therapy for chronic neuropathic pain in spinal cord injury (SCI) patients. Four patients with SCI and neuropathic pain participated ...
KEY FINDING: The study found good satisfaction and acceptance of virtual walking therapy among the participants.
Journal of Neuroinflammation, 2024 • August 22, 2024
This study aimed to explore the roles of oligodendrocytes and their interactions with other glial cells in neuropathic pain (NP) development using a chronic constriction injury (CCI) model in mice and...
KEY FINDING: Neuropathic pain peaked on day 7 after chronic constriction injury in mice, concurrent with myelin lesions in both the spinal cord and sciatic nerve.
Trials, 2024 • January 1, 2024
This study is a double-blind, randomized controlled trial designed to assess the impact of aerobic exercise on neuropathic pain and quality of life in individuals with chronic paraplegia. Participants...
KEY FINDING: The trial aims to provide new knowledge about the effectiveness of aerobic exercise in improving neuropathic pain and QoL in individuals with chronic paraplegia.
Interventional Pain Medicine, 2024 • June 5, 2024
This retrospective study investigates the safety of cervical transforaminal epidural steroid injections (TFESIs) using non-particulate steroids over a 17-year period at an academic institution. The st...
KEY FINDING: No catastrophic complications (spinal cord injury, stroke, death or other) were reported in 6241 cervical TFESIs performed between 2004 and 2021.