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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Orthopedics Research

Browse the latest research summaries in the field of orthopedics for spinal cord injury patients and caregivers.

Showing 61-70 of 452 results

PharmacologyGeneticsOrthopedics

Astragaloside IV attenuates IL‑1β‑induced intervertebral disc degeneration through inhibition of the NF‑κB pathway

Journal of Orthopaedic Surgery and Research, 2022 • December 5, 2022

This study investigates the potential of Astragaloside IV (AS IV) to treat intervertebral disc degeneration (IDD) by alleviating inflammation, apoptosis, and extracellular matrix (ECM) degeneration in...

KEY FINDING: AS IV effectively alleviated IL-1β-induced inflammation, apoptosis, and extracellular matrix degeneration in NPCs.

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SurgeryOrthopedicsSpinal Disorders

Analysis of surgical strategies and efficacy in the treatment of Os odontoideum with atlantoaxial dislocation

Journal of Orthopaedic Surgery and Research, 2023 • January 8, 2023

This study retrospectively analyzed 56 patients with os odontoideum (OO) and atlantoaxial dislocation (AAD) to determine effective surgical strategies. AAD was classified into four types, and surgical...

KEY FINDING: OO patients with irreducible AAD can be treated by translateral mass release or transoral release combined with posterior fixation and fusion

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Assistive TechnologySurgeryOrthopedics

Robot-assisted anterior transpedicular screw fixation with 3D printed implant for multiple cervical fractures: A case report

Medicine, 2022 • December 1, 2022

This case report presents a novel approach to treating multiple cervical fractures using robot-assisted anterior transpedicular screw (ATPS) fixation combined with a custom 3D printed implant. The pat...

KEY FINDING: Robot-assisted ATPS fixation with a 3D printed implant is a feasible, safe, and accurate method for treating multiple cervical fractures.

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Spinal Cord InjuryOrthopedicsBiomechanics

Biomechanical analysis of spinal cord injury during scoliosis correction surgery

Front. Bioeng. Biotechnol., 2024 • July 2, 2024

This study investigates the biomechanical changes in the spinal cord during scoliosis correction surgery using patient-specific finite element models. The aim is to understand the mechanisms of spinal...

KEY FINDING: Stress concentration in the spinal cord was observed in patients with poor prognosis, aligning with their clinical manifestations of neurological dysfunction. For example, patient a showed stress concentration at the T8-T9 segments, consistent with paraplegia at that level.

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SurgeryOrthopedics

A novel surgical management for pediatric patients with irreducible atlantoaxial dislocation: Transoral intraarticular cage distraction and fusion with C-JAWS staple fixation

Frontiers in Surgery, 2023 • January 6, 2023

This study introduces a novel surgical technique for treating pediatric patients with irreducible atlantoaxial dislocation (IAAD) using a transoral approach involving intraarticular cage distraction a...

KEY FINDING: The surgeries were successfully performed in all patients without injuries to spinal cord, nerve and blood vessel.

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Spinal Cord InjurySurgeryOrthopedics

Cervical single open-door laminoplasty with or without local lateral mass screw fixation and fusion to treat cervical spinal cord injuries accompanied by segmental spinal canal stenosis

Frontiers in Surgery, 2023 • January 4, 2023

This retrospective study evaluated the efficacy of cervical single open-door laminoplasty with and without local lateral mass screw fixation and fusion for treating cervical spinal cord injuries accom...

KEY FINDING: Both laminoplasty alone and laminoplasty with fusion improved neurological function.

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NeurologySurgeryOrthopedics

Treatment of lower cervical spine fracture with ankylosing spondylitis by simple long anterior cervical plate: a retrospective study of 17 cases

Frontiers in Neurology, 2024 • July 2, 2024

This retrospective study evaluated the effectiveness of anterior internal fixation using a long anterior cervical plate for treating lower cervical spine fractures in 17 patients with ankylosing spond...

KEY FINDING: No postoperative neurological deterioration occurred in any of the 17 cases.

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SurgeryTraumaOrthopedics

Frequency and Causes of Traumatic and Non-traumatic Spinal Injury Reported at Two Major Tertiary Care Hospitals of Khyber Pakhtunkhwa

Cureus, 2023 • January 1, 2023

This study investigated the frequency and causes of spinal cord injuries (SCIs) in two major hospitals in Peshawar, Pakistan, distinguishing between traumatic and non-traumatic origins. Traumatic inju...

KEY FINDING: The study found that 35% of patients experienced spinal disorders due to trauma, with falls (42%), road traffic accidents (29%), and weight lifting (21%) being the primary causes.

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NeurologyOrthopedicsMusculoskeletal Medicine

CORR Insights®: Can a Nomogram Predict Survival After Treatment for an Ankylosing Spondylitis Cervical Fracture in a Patient With Neurologic Impairment? A National, Multicenter Study

Clin Orthop Relat Res, 2023 • February 8, 2023

The article discusses the increasing incidence and severity of cervical spine fractures in patients with ankylosing spondylitis (AS). It highlights a study by Bai et al. that developed a nomogram to p...

KEY FINDING: A study by Bai et al. developed a formula to predict survival in patients with cervical spine fracture and underlying ankylosis, identifying factors independently associated with increased mortality risk.

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GeneticsPediatricsOrthopedics

Which is the best femoral implant in children with osteogenesis imperfecta? a retrospective cohort study of 783 procedures

BMC Musculoskeletal Disorders, 2023 • February 3, 2023

This retrospective cohort study compared the clinical outcomes of four different femoral implants (telescopic rod, plate and screws, elastic nail, and non-elongating rod) in children with osteogenesis...

KEY FINDING: Children with Sillence type III (severe OI) had the highest revision rate and shortest implant survival period, while those with type I (mild OI) had the lowest revision rate and longest survival period.

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