Browse the latest research summaries in the field of orthopedics for spinal cord injury patients and caregivers.
Showing 371-380 of 452 results
Asian Spine Journal, 2014 • April 1, 2014
The study evaluated the neurologic outcome after anterior decompressive surgery in late neglected cases of mechanical cervical spinal cord disorder. It focused on patients admitted 3 months after spin...
KEY FINDING: Anterior cervical decompression with interbody fusion is effective in improving functional outcomes, even in late-presenting incomplete quadriplegic patients.
HAND, 2014 • March 4, 2014
The study evaluated surgical procedures to reconstruct pinch and hook functions in tetraplegic patients, comparing different tendon transfer and tenodesis techniques. Results indicated that both BR an...
KEY FINDING: Both brachioradialis (BR) and pronator teres (PT) tendon transfers were equally effective for reconstructing key pinch.
PRS Global Open, 2021 • June 22, 2021
Targeted muscle reinnervation and regenerative peripheral nerve interfaces are increasingly utilized strategies to mitigate phantom and residual limb pain in amputees. In this case report, the authors...
KEY FINDING: The patient reported a decrease in pain score from eight to four upon activation of the nerve stimulator postoperatively.
International Journal of Biomaterials, 2021 • June 19, 2021
The study evaluated various fixation methods for hydrogel constructs in minipig cartilage defects, comparing fibrin glue, BioGlue®, suturing, and press-fit techniques. Results showed that fixation in ...
KEY FINDING: Fixation rates were below 50% for all tested methods in chondral defects.
Stem Cells International, 2021 • August 24, 2021
This study investigates the use of umbilical cord mesenchymal stem cells (UC-MSCs) combined with hydroxyapatite (HA) scaffolds for treating vertebral bone defects caused by spondylitis tuberculosis. T...
KEY FINDING: The study found increased bone formation at the defect site over six months, with 75-100% of the bone area showing formation. This suggests the stem cell and scaffold combination supports bone regeneration.
Frontiers in Bioengineering and Biotechnology, 2021 • November 30, 2021
The study aimed to enhance the biological performance of 3D-printed Ti6Al4V implants by modifying their surface with a polydopamine (PDA) coating. In vitro results showed that the PDA coating improved...
KEY FINDING: PDA coating enhanced the hydrophilicity of 3D-printed Ti6Al4V implants.
EBioMedicine, 2022 • January 1, 2022
This study investigates the impact of allergy-induced systemic inflammation on tendon quality using a mouse model and human health survey data. The findings demonstrate that allergic inflammation nega...
KEY FINDING: Tendons from allergic mice exhibited a significant reduction in both elastic modulus and tensile stress.
eBioMedicine, 2022 • February 1, 2022
This study investigates the therapeutic efficacy of combining ultra-purified human bone marrow mesenchymal stem cells (RECs) and a bioresorbable gel for IVD regeneration after discectomy in a sheep mo...
KEY FINDING: Co-culturing RECs and nucleus pulposus cells (NPCs) in the gel significantly increased gene expression of NPC markers, growth factors, and extracellular matrix compared to monocultures.
Aging and Disease, 2022 • April 1, 2022
This study investigates the role of CB2R in intervertebral disc degeneration (IVDD) by examining its effects on nucleus pulposus cell (NPC) senescence both in vitro and in vivo. The study found that C...
KEY FINDING: CB2R expression is decreased in degenerated nucleus pulposus (NP) tissues from both human IVDD patients and rat acupuncture IVDD models, while the expression of p16INK4a increased.
JOR Spine, 2022 • January 1, 2022
Intradiscal injection is a minimally invasive technique used for low back pain, with its safety and effectiveness supported by clinical trials. Various medications and biological agents are used, but ...
KEY FINDING: Intradiscal injection is a minimally invasive outpatient procedure that can improve pain quality for patients with LBP or lumbar disc herniation (LDH).