Browse the latest research summaries in the field of oncology for spinal cord injury patients and caregivers.
Showing 111-120 of 200 results
Cell Death and Disease, 2025 • January 29, 2025
The study demonstrates that the nuclear orphan receptor NR2F6 represses the expression of the activating receptor NKp46, an established key player in NK cell-mediated cytotoxicity during infection and...
KEY FINDING: NR2F6 represses the expression of the activating receptor NKp46, a key player in NK cell-mediated cytotoxicity.
Genome Medicine, 2023 • February 15, 2023
This study investigated the tumor microenvironment (TME) remodeling in non-small cell lung cancer (NSCLC) patients after neoadjuvant PD-1 blockade combined with chemotherapy using single-cell RNA sequ...
KEY FINDING: Cancer cells from patients who responded well to treatment showed signs of presenting antigens, which helps the immune system recognize and attack them.
Molecular Oncology, 2021 • January 24, 2021
This study benchmarks HLA genotyping on TCGA data using multiple tools to generate reliable HLA genotyping results. It finds that HLA class I genotyping is generally better than class II genotyping, w...
KEY FINDING: POLY-SOLVER, OptiType, and xHLA show high accuracy in HLA class I genotyping, with accuracies of 0.954, 0.949, and 0.937, respectively.
The Journal of Spinal Cord Medicine, 2017 • March 1, 2017
This study addresses the rehabilitation of patients with spinal cord dysfunction (SCDys) caused by tumors. It includes a literature review, a survey of healthcare professionals, and expert opinions to...
KEY FINDING: Most respondents reported that people with benign tumors were routinely admitted for rehabilitation but only a smaller percentage reported that people with malignant tumors were routinely admitted.
The Journal of Spinal Cord Medicine, 2015 • January 1, 2015
This study investigates the effectiveness of inpatient rehabilitation for patients with malignant spinal cord compression (MSCC) compared to those with non-traumatic spinal cord injury (NT-SCI). The r...
KEY FINDING: Patients with MSCC showed significant improvement in the Functional Independence Measure (FIM) scores during inpatient rehabilitation.
Medicine, 2015 • February 1, 2015
This case report presents two cases of spinal neurilemmoma in a 29-year-old man and an 11-year-old boy, highlighting the clinical and radiographic features of this rare condition. Both patients underw...
KEY FINDING: Intraspinal neurilemmoma, though rare, should be considered when diagnosing spinal cord compression.
Phys Med Rehabil Clin N Am, 2017 • February 1, 2017
Spinal tumors can be classified into extradural, intradural extramedullary and intradural intramedullary tumors. Management of spinal tumors varies according to the stability of the spine, neurologica...
KEY FINDING: Localized spine pain is the most common symptom in patients with epidural spinal cord compression at the time of diagnosis.
Annals of Rehabilitation Medicine, 2016 • December 1, 2016
This case series reports on the effects of radiation therapy (RT) in three patients with established neurogenic heterotopic ossification (HO) following brain injury. The study found that RT led to dec...
KEY FINDING: Radiation therapy resulted in decreased pain and increased range of motion in patients with established neurogenic heterotopic ossification.
British Journal of Cancer, 2006 • January 24, 2006
This retrospective audit assessed the care of 174 patients with MSCC at a UK cancer centre over a 12-month period, revealing shortcomings in pain assessment, patient mobility, and rehabilitation plann...
KEY FINDING: The common primary tumor diagnoses were lung (29%), prostate (19%), and breast (13%).
Acta Orthopaedica, 2017 • April 1, 2017
This study evaluated the outcomes of surgical treatment for metastatic spinal cord compression (MSCC) as the initial manifestation of malignancy (IMM) in 69 patients. The primary outcomes assessed wer...
KEY FINDING: Postoperative survival depends on the type of primary tumor, with prostate cancer and myeloma showing the longest survival.