Browse the latest research summaries in the field of neurorehabilitation for spinal cord injury patients and caregivers.
Showing 231-240 of 344 results
Scientific Reports, 2018 • August 10, 2018
This study evaluated the long-term efficacy and safety of aFGF in treating chronic SCI patients over a 48-month period. The aFGF was administered directly to the injured spinal cord during surgery and...
KEY FINDING: Significant improvements were observed in ASIA impairment scales, motor scores, pin prick, light touch, and FIM motor subtotal scores in both cervical and thoracolumbar SCI groups.
Journal of NeuroEngineering and Rehabilitation, 2017 • March 30, 2017
The study investigates the impact of body weight support (BWS) on gait patterns in healthy individuals during overground walking using a cable-based robotic system (FLOAT). Results indicate that parti...
KEY FINDING: Healthy individuals maintain consistent walking kinematics even when unloaded by half their body weight, suggesting the support system permits physiological gait.
Annu Rev Med, 2004 • January 1, 2004
The prospects for successful clinical trials of neuroprotective and neurorestorative interventions for patients with acute and chronic myelopathies depend on preclinical animal models of injury and re...
KEY FINDING: Neurotrophic factors, such as BDNF, can reverse atrophy of rubrospinal neurons and promote spinal axon regeneration, even when administered long after SCI.
J Neurol Neurosurg Psychiatry, 2005 • May 1, 2005
This study demonstrates that systematic collection, analysis, and interpretation of standardised clinical outcomes data are feasible within routine clinical practice. Inpatient rehabilitation is effec...
KEY FINDING: Patients in the neurorehabilitation unit showed improvements in functional ability, as measured by the Barthel Index (BI) and Functional Independence Measure (FIM).
Neural Plasticity, 2017 • April 20, 2017
This special issue focuses on the effectiveness and mechanisms of neurorehabilitation in inducing neural plasticity and functional recovery following neurological diseases. Articles in this issue cove...
KEY FINDING: EMG-controlled neuromuscular electrical stimulation improved arm and hand function and induced plastic changes in intracortical and spinal interneurons following stroke.
Neurorehabil Neural Repair, 2007 • January 1, 2007
Two multicenter randomized clinical trials (MRCT), the Extremity Constraint Induced Therapy Evaluation (EXCITE) to improve upper extremity function after stroke and the Spinal Cord Injury Locomotor Tr...
KEY FINDING: In EXCITE, the CIMT group increased the speed at which it completed a battery of standardized tasks with the affected hand compared to the control group that did not receive any therapy.
Journal of NeuroEngineering and Rehabilitation, 2007 • January 23, 2007
This study explores the use of biofeedback in robot-assisted gait training to improve patient performance and motivation. It addresses the challenge of reduced therapist-patient interaction in robotic...
KEY FINDING: Biofeedback values correlated well with the different activity levels of the subjects, indicating its potential to reflect gait performance accurately.
Journal of NeuroEngineering and Rehabilitation, 2007 • February 9, 2007
Modern gait rehabilitation emphasizes task-specific and repetitive training, moving away from tone-inhibiting approaches. Gait rehabilitation machines facilitate this by allowing patients to practice ...
KEY FINDING: The DEGAS study showed that machine-supported training (Gait Trainer GT I) resulted in superior gait ability and competence in activities of daily living compared to conventional gait training in stroke patients.
J Biomech, 2007 • January 1, 2007
This study compared three mathematical muscle models (linear, 2nd order nonlinear, and Hill Huxley type nonlinear) for predicting force properties in trained and untrained paralyzed soleus muscles of ...
KEY FINDING: Nonlinear models, especially the Hill Huxley type, predict paralyzed muscle force properties more accurately than linear models.
Dev Neurobiol, 2007 • August 1, 2007
This paper reviews the challenges of translating preclinical research on neural repair, particularly for stroke and spinal cord injury, into effective clinical therapies. It emphasizes the limitations...
KEY FINDING: Rodent models of neural repair for stroke and spinal cord injury have limitations due to differences in brain size, axonal regeneration distances, and immune responses compared to humans.