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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Neuroimaging Research

Browse the latest research summaries in the field of neuroimaging for spinal cord injury patients and caregivers.

Showing 31-40 of 95 results

NeuroimagingNeurologyNeurorehabilitation

EEG hyperscanning in motor rehabilitation: a position paper

J NeuroEngineering Rehabil, 2021 • June 1, 2021

This paper proposes an approach to study EEG-HS in different patient populations, such as stroke, spinal cord injury (SCI), Parkinson’s disease (PD), and traumatic brain injury (TBI). The authors addr...

KEY FINDING: Inter-brain synchronization may not exclusively depend on the precise execution of a particular movement, suggesting that self-determined engagement during gestural imitation is more informative.

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Spinal Cord InjuryNeuroimagingRehabilitation

Lateral corticospinal tract and dorsal column damage: predictive relationships with motor and sensory scores at discharge from acute rehabilitation after spinal cord injury.

Arch Phys Med Rehabil, 2022 • January 1, 2022

This retrospective study examined the predictive relationship between the integrity of specific spinal cord tracts and sensorimotor function in individuals with SCI. The study found that LCST integrit...

KEY FINDING: The integrity of the lateral corticospinal tract (LCST) showed a significant predictive relationship with lower extremity motor function at discharge.

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Spinal Cord InjuryNeuroimagingMedical Imaging

Generic acquisition protocol for quantitative MRI of the spinal cord

Nat Protoc, 2021 • October 1, 2021

The study presents a prospectively harmonized consensus protocol, called the spine generic protocol, for acquiring high-quality qMRI of the human cervical SC at 3 Tesla (T) across GE, Philips and Siem...

KEY FINDING: The spine generic protocol provides a harmonized approach for acquiring high-quality qMRI of the human cervical spinal cord at 3T across the three main MRI manufacturers.

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NeuroimagingHealthcare

Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers

Scientific Data, 2021 • August 16, 2021

This study introduces a standardized spine generic quantitative MRI protocol and associated datasets acquired across multiple centers and MRI manufacturers. The datasets, consisting of single-subject ...

KEY FINDING: The spine generic protocol demonstrated high reproducibility across different MRI sites and manufacturers, with an average inter-site coefficient of variation of less than 5% for most metrics.

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NeuroimagingNeurology

The Frequency and Associated Factors of Asymmetrical Prominent Veins: A Predictor of Unfavorable Outcomes in Patients with Acute Ischemic Stroke

Neural Plasticity, 2021 • September 17, 2021

This study aimed to determine the frequency and associated risk factors of asymmetrical prominent veins (APV) in patients with acute ischemic stroke (AIS) within 12 hours of symptom onset. The study f...

KEY FINDING: The frequency of high APV (volume ≥10 mL) was 46.05% in patients with AIS within 12 hours of symptom onset.

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NeuroimagingNeurology

Characterizing the Neuroimaging and Histopathological Correlates of Cerebral Small Vessel Disease in Spontaneously Hypertensive Stroke-Prone Rats

Frontiers in Neurology, 2021 • November 30, 2021

The study characterized four stages of CSVD severity in SHRSP at different time points, ranging from pre-hypertensive to advanced CSVD. Quantitative analyses of brain MRI enable identification of in v...

KEY FINDING: SHRSP showed a significantly higher prevalence of small subcortical hyperintensities on T2w imaging that progressed in size and frequency with aging compared to WKY controls.

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Spinal Cord InjuryNeuroimagingPediatrics

Clinical Utility of Diffusion Tensor Imaging as a Biomarker to Identify Microstructural Changes in Pediatric Spinal Cord Injury

Top Spinal Cord Inj Rehabil, 2022 • April 1, 2022

This prospective study examined the utility of diffusion tensor imaging (DTI) as a biomarker for assessing microstructural changes in pediatric spinal cord injury (SCI). The study compared DTI metrics...

KEY FINDING: A significant positive association was found between fractional anisotropy (FA) and upper extremity muscle strength in participants with SCI, indicating that higher muscle strength is associated with higher FA values.

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NeuroimagingMental Health

Persistent Dissociation and its Neural Correlates Uniquely Predict Worse Outcomes after Trauma Exposure

Am J Psychiatry, 2022 • September 1, 2022

This study investigated the predictive capacity of persistent derealization, a type of dissociation, for adverse psychiatric outcomes following acute trauma. The research found that derealization, mea...

KEY FINDING: Derealization was associated with increased activity in the ventromedial prefrontal cortex (vmPFC) during an emotion reactivity task.

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NeuroimagingMental HealthNeurology

Structural covariance of the ventral visual stream predicts posttraumatic intrusion and nightmare symptoms: a multivariate data fusion analysis

Translational Psychiatry, 2022 • August 22, 2022

This study investigated the role of the ventral visual stream (VVS) in PTSD using multimodal MRI data from trauma-exposed individuals. A structural covariance network (SCN) within the VVS was identifi...

KEY FINDING: A structural covariance network (SCN) of the ventral visual stream (VVS) was identified, and its strength was positively associated with PTSD symptoms two weeks after trauma.

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NeuroimagingNeurologyMedical Imaging

Individual variations of the human corticospinal tract and its hand-related motor fibers using diffusion MRI tractography

Brain Imaging Behav, 2020 • June 1, 2020

This study introduces a novel method using dMRI tractography to delineate the CST and isolate its hand motor representation (HMFTs). The study quantifies the variability of these tracts in 37 healthy ...

KEY FINDING: The study successfully delineated the CST and HMFTs using a novel dMRI tractography method.

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