Browse the latest research summaries in the field of neuroimaging for spinal cord injury patients and caregivers.
Showing 41-50 of 95 results
Frontiers in Neurology, 2019 • November 1, 2019
The study proposes a distance-based neurorehabilitation evaluation method using rs-fMRI and linear SVM to monitor brain function changes after a rehabilitation program. The method involves training an...
KEY FINDING: The classifier successfully separated patients and healthy controls based on their resting-state fMRI data.
Brain Communications, 2023 • December 19, 2022
This study introduces a neuroimaging and analysis protocol to identify spinal cord levels at the lumbosacral enlargement, assess anatomical variability, locate epidural stimulation electrodes, and lin...
KEY FINDING: The length of the spinal column and spinal cord, location of the conus tip, and the relationship between spinal cord and vertebral levels at the lumbosacral enlargement vary across individuals.
Neural Plasticity, 2020 • March 10, 2020
This study investigated the reorganization of insular subregions in individuals suffering from neuropathic pain (NP) after incomplete spinal cord injury (ISCI) to disclose the underlying mechanism of ...
KEY FINDING: Compared to ISCI individuals without neuropathic pain, those with neuropathic pain showed increased functional connectivity between the left posterior insula and the right cerebellum VIIb and VIII, as well as Brodmann area 37.
Neuroimage, 2020 • August 15, 2020
This study used fMRI to quantitatively assess the spatial distribution of spinal cord activity from left- and right-sided tactile stimulation of the lateral shoulders and dorsal third digits of the ha...
KEY FINDING: Tactile stimulation resulted in activity localized primarily to the ipsilateral hemicord, with the left- and right-sided stimuli having more activation in the respective ipsilateral hemicord.
NeuroImage: Clinical, 2020 • July 25, 2020
The study investigated alterations in brain activity, specifically using power spectral density (PSD) analysis of resting-state fMRI, in patients with spinal cord injury (SCI) experiencing neuropathic...
KEY FINDING: Lower PSD values in supplementary motor and medial prefrontal areas were associated with greater pain severity and poorer postural balance and mobility in patients with SCI.
Sci. Adv., 2020 • August 7, 2020
The study used DTI and NODDI to investigate white matter changes after mTBI, correlating them with neuropsychological performance. Early microstructural white matter changes in mTBI are driven by incr...
KEY FINDING: Early lower fractional anisotropy (FA) and neurite density index (NDI), and early higher mean diffusivity (MD) and free water fraction (FISO) were observed in mTBI patients compared to controls.
Scientific Reports, 2020 • August 5, 2020
This study characterizes neurodegenerative and reorganizational changes across the basal ganglia-thalamic circuit after SCI using advanced neuroimaging measures, in vivo. We demonstrate a dynamic patt...
KEY FINDING: Surface area contracted in the motor (i.e. lower extremity) and pulvinar thalamus, and striatum; and expanded in the motor thalamus and striatum in patients compared to controls over 2-years.
Hum Brain Mapp, 2021 • January 1, 2021
This study validated a simultaneous analysis tool (SPM-BSC) for brain and cervical cord MRI data within the SPM framework, comparing trauma-induced changes in SCI patients to healthy controls. The SPM...
KEY FINDING: The SPM-BSC approach identified trauma-induced changes in the sensorimotor system of the brain and spinal cord in SCI patients, consistent with findings from established analysis methods.
Neurorehabilitation and Neural Repair, 2021 • January 1, 2021
This study assessed the predictive value of midsagittal tissue bridges for American Spinal Injury Association (ASIA) Impairment Scale (AIS) grade conversion and SCI patient stratification into recover...
KEY FINDING: Larger ventral and dorsal tissue bridges were associated with higher AIS conversion rates 12 months post-SCI.
Front. Syst. Neurosci., 2020 • October 21, 2020
This study investigated the relationship between spinal cord MRI markers and the recovery of volitional leg movement with spinal cord epidural stimulation (scES) in individuals with clinically motor c...
KEY FINDING: The amount and location of spared spinal cord tissue at the lesion site were unrelated to the ability to generate volitional lower limb movements with scES.