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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Neuroimaging Research

Browse the latest research summaries in the field of neuroimaging for spinal cord injury patients and caregivers.

Showing 21-30 of 95 results

Spinal Cord InjuryNeuroimagingNeurology

The gray matter atrophy and related network changes occur in the higher cognitive region rather than the primary sensorimotor cortex after spinal cord injury

PeerJ, 2023 • October 9, 2023

This study explored brain structural and functional changes in SCI patients using fMRI, revealing gray matter atrophy in frontal, temporal, and insular cortices. Functional connectivity analysis showe...

KEY FINDING: SCI patients showed decreased GMV in the frontal, temporal, and insular cortices compared to healthy controls.

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NeuroimagingNeurologyResearch Methodology & Design

Contrast-medium injury of spinal cord after cerebral angiography using nonionic contrast agents: A case report and literature review

Medicine, 2023 • December 1, 2023

This case report details an instance of contrast-induced spinal cord injury (CIS) occurring after cerebral angiography with a nonionic contrast agent, Ioversol. The patient initially experienced contr...

KEY FINDING: A patient developed contrast-induced spinal cord injury (CIS) following cerebral angiography using a nonionic contrast agent (Ioversol). This is a rare occurrence, as CIS is more commonly associated with ionic contrast agents.

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Spinal Cord InjuryNeuroimagingNeurology

Body size interacts with the structure of the central nervous system: A multi-center in vivo neuroimaging study

bioRxiv preprint, 2024 • May 1, 2024

The study investigates the relationship between body size parameters and brain and spinal cord MRI metrics in 267 healthy adults. Results indicate that body height correlates with brain gray matter vo...

KEY FINDING: Body height correlated moderately with brain gray matter volume and spinal cord white matter area.

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Spinal Cord InjuryNeuroimagingPediatrics

The relationship between the structural changes in the cervical spinal cord and sensorimotor function of children with thoracolumbar spinal cord injury (TLSCI)

Spinal Cord, 2024 • June 1, 2024

This study investigates structural changes in the cervical spinal cord of children with TLSCI and their relationship with sensorimotor function, aiming to identify objective imaging biomarkers. The st...

KEY FINDING: CSA and LRW in the AIS A/B group were significantly lower than those in the TD group and the AIS C/D group, indicating spinal cord atrophy is related to the severity of the injury.

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Spinal Cord InjuryNeuroimagingNeurology

Delayed cerebrovascular reactivity in individuals with spinal cord injury in the right inferior parietal lobe: a breath-hold functional near-infrared spectroscopy study

medRxiv preprint, 2024 • June 4, 2024

The study examined differences in CVR amplitude and delays between SCI and AB individuals using fNIRS during a hypercapnic breath-holding task. It reports significantly delayed CVR in the right inferi...

KEY FINDING: Individuals with SCI showed significantly delayed CVR in the right inferior parietal lobe compared to able-bodied controls.

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NeuroimagingNeurologyPediatrics

Alterations in cortical thickness and volumes of subcortical structures in pediatric patients with complete spinal cord injury

CNS Neurosci Ther, 2024 • June 3, 2024

This study investigated the changes in cortical thickness and subcortical gray matter structures in children with complete spinal cord injury (CSCI) compared to healthy controls (HCs). The results sho...

KEY FINDING: Pediatric CSCI patients showed decreased cortical thickness in the right precentral gyrus, superior temporal gyrus, and posterior segment of the lateral sulcus compared to healthy controls.

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NeuroimagingNeurologyRehabilitation

The importance of brain mapping for rehabilitation in birth nonprogressive neuromuscular diseases

Front. Neuroimaging, 2024 • July 15, 2024

This review emphasizes the scarcity of research on brain mapping in children with birth motor deficits of non-brain origin, highlighting a gap in the application of brain stimulation therapy despite s...

KEY FINDING: Individuals with birth-related motor conditions exhibit unique central adaptation features compared to those with acquired conditions, such as nonsomatotopic presentation of involved muscles in the sensorimotor cortex.

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NeuroimagingMedical Imaging

EPISeg: Automated segmentation of the spinal cord on echo planar images using open-access multi-center data

bioRxiv preprint, 2025 • January 27, 2025

This study introduces EPISeg, a deep learning-based method for automated spinal cord segmentation on gradient-echo EPI images, commonly used in fMRI. EPISeg addresses challenges related to heterogeneo...

KEY FINDING: EPISeg significantly improves spinal cord segmentation quality compared to existing methods.

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Spinal Cord InjuryNeuroimagingPain Management

Differences in resting cerebellar and prefrontal cortical blood flow in spinal cord injury-related neuropathic pain: A brief report

The Journal of Spinal Cord Medicine, 2021 • July 1, 2020

This pilot study aimed to identify differences in resting cerebral blood flow between individuals with spinal cord injury (SCI)-related neuropathic pain (NP) and healthy controls using arterial spin l...

KEY FINDING: Individuals with SCI-related neuropathic pain exhibited significantly reduced resting blood flow in the cerebellum (specifically Crus I/II), the rostral ventromedial medulla, and the left insular cortex compared to healthy controls.

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NeuroimagingNeurology

Brain microstructural and metabolic alterations detected in vivo at onset of the first demyelinating event

Brain, 2021 • April 27, 2021

The study investigates microstructural and metabolic alterations in the brains of patients at the onset of their first neurological episode suggestive of demyelination using neurite orientation disper...

KEY FINDING: Patients showed increased axonal dispersion in normal-appearing white matter, especially in the corpus callosum, along with axonal degeneration and sodium accumulation.

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