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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Neuroimaging Research

Browse the latest research summaries in the field of neuroimaging for spinal cord injury patients and caregivers.

Showing 91-95 of 95 results

Spinal Cord InjuryNeuroimagingMedical Imaging

Diffusion tensor imaging of spinal microstructure in healthy adults: improved resolution with the readout segmentation of long variable echo-trains

Neural Regeneration Research, 2017 • December 1, 2017

This study investigated the use of the RESOLVE sequence in diffusion tensor imaging (DTI) to improve the resolution of spinal cord microstructure imaging in healthy adults. The results showed that the...

KEY FINDING: The RESOLVE sequence significantly increased the resolution of the diffusion images and improved the median signal-to-noise ratio of the middle (C4–6) and lower (C7–T1) cervical segments to the level of the upper cervical segment.

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NeuroimagingNeurology

Imaging outcome measures of neuroprotection and repair in MS A consensus statement from NAIMS

Neurology, 2019 • March 12, 2019

This study summarizes current and emerging imaging techniques for assessing neuroprotection and repair in multiple sclerosis (MS). It provides a consensus opinion on each technique's utility in clinic...

KEY FINDING: Conventional MRI measures in acute lesions can assess myelin integrity and repair, leveraging routinely collected data, though lacking pathologic specificity and requiring signal normalization.

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NeuroimagingRegenerative MedicineNeurology

Three-Dimensional In vivo Magnetic Resonance Imaging (MRI) of Mouse Facial Nerve Regeneration

Frontiers in Neurology, 2019 • April 2, 2019

The study establishes an MRI protocol in mice to monitor the regeneration of small nerves without contrast agents, focusing on the facial nerve. MRI scans revealed nerve hyperintensity after injury, w...

KEY FINDING: Nerve injury caused hyperintense signal in T2-weighted images, and an increase in nerve size of the proximal and distal nerve stumps were observed.

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NeuroimagingNeurology

Functional connectivity after hemispherectomy

Quant Imaging Med Surg, 2020 • May 1, 2020

This editorial comments on a study by Kliemann et al. that investigated functional connectivity in individuals who had undergone hemispherectomy. The key finding was that despite having only one hemis...

KEY FINDING: Interhemispheric connectivity in brains with only one hemisphere is strikingly similar to the functional network organization in brains with two hemispheres.

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NeuroimagingNeurology

Multiexponential T2 and Magnetization Transfer MRI of Demyelination and Remyelination in Murine Spinal Cord

Neuroimage, 2009 • May 1, 2009

This study investigated the use of quantitative MRI techniques (qT2 and MTR) to assess demyelination and remyelination in a mouse model of multiple sclerosis. Lysolecithin was injected into the spinal...

KEY FINDING: The myelin water fraction (MWF) and geometric mean T2 value significantly decreased at 14 days post-injection, indicating demyelination. By 28 days, these values returned to control levels, suggesting remyelination.

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