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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Mental Health Research

Browse the latest research summaries in the field of mental health for spinal cord injury patients and caregivers.

Showing 271-280 of 289 results

Spinal Cord InjuryMental HealthPain Management

Pain Intensity and Its Association with Negative Mood States in Patients with Spinal Cord Injury

Pain Ther, 2013 • October 12, 2013

This study examined the relationship between pain intensity and negative mood states in adults with SCI. The results showed that a significant proportion of participants reported clinically significan...

KEY FINDING: Clinically significant pain intensity was found in 52% of the 107 participants.

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Spinal Cord InjuryMental HealthPain Management

Effects of chronic pain on function, depression, and sleep among patients with traumatic spinal cord injury

Ann Saudi Med, 2014 • May 1, 2014

This study assessed chronic pain and its effects on functional status, depression, and sleep quality in patients with traumatic SCI. It was observed that “Pain Severity” was significantly higher in th...

KEY FINDING: A positive correlation was observed between “Pain Severity” and HAM-D and PSQI.

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Spinal Cord InjuryMental HealthPain Management

Cluster Analysis and Chronic Pain: An Empirical Classification of Pain Subgroups in a Spinal Cord Injury Sample

Rehabil Psychol, 2005 • November 1, 2005

The study aimed to identify homogeneous pain subgroups within a spinal cord injury (SCI) population using cluster analysis based on pain intensity, pain interference, and depression. Multivariate clus...

KEY FINDING: Four distinct SCI pain subgroups were identified: Low Pain, Positive Adaptation to Pain, Minimal Distress, and Chronic Pain Syndrome.

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Spinal Cord InjuryMental HealthRehabilitation

Effects of Adult Romantic Attachment and Social Support on Resilience and Depression in Individuals with Spinal Cord Injuries

Top Spinal Cord Inj Rehabil, 2015 • January 1, 2015

This study investigated the relationships between adult romantic attachment, perceived social support, depression, and resilience in individuals with SCI undergoing inpatient rehabilitation. The resea...

KEY FINDING: Individuals with higher levels of attachment avoidance have lower perceived social support, which in turn relates to lower perceived resilience.

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PharmacologyPhysiologyMental Health

Differential acute impact of therapeutically effective and overdose concentrations of lithium on human neuronal single cell and network function

Translational Psychiatry, 2021 • April 19, 2021

This study investigates the acute effects of therapeutic and overdose concentrations of lithium on human iPSC-derived cortical neurons using MEA and patch-clamp techniques. The findings reveal that th...

KEY FINDING: Therapeutic concentrations of lithium increase neuronal excitability and network activity in human iPSC-derived cortical neurons.

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Regenerative MedicineMental HealthNeurology

Assessment of Swim Endurance and Swim Behavior in Adult Zebrafish

J Vis Exp, null • June 24, 2022

This study describes methods to quantify swim endurance and swim behavior in adult zebrafish using a swim tunnel. Zebrafish are subjected to increasing water current velocities to measure swim enduran...

KEY FINDING: Wild-type zebrafish swam for 41 minutes before exhaustion, establishing a baseline for motor function.

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Mental HealthNeurologyNutrition & Dietetics

Impaired hippocampal neurogenesis in vitro is modulated by dietary-related endogenous factors and associated with depression in a longitudinal ageing cohort study

Molecular Psychiatry, 2022 • July 7, 2022

Using serum samples from a longitudinal, population-based ageing cohort, we provide evidence to support that blood-borne factors, via the systemic milieu of participants, influence the fate of hippocam...

KEY FINDING: Reduced cell death and increased neuronal differentiation were associated with later life depressive symptomatology.

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Mental HealthGeneticsBioinformatics

Integrated co-expression network analysis uncovers novel tissue-specific genes in major depressive disorder and bipolar disorder

Frontiers in Psychiatry, 2022 • August 23, 2022

This study used integrated co-expression network analysis to identify tissue-specific gene modules and functions in major depressive disorder (MDD) and bipolar disorder (BP). The analysis revealed nin...

KEY FINDING: Nine tissue-specific modules were identified in MDD across four tissues, and six modules in BP.

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Mental HealthPain ManagementRehabilitation

Comparative effectiveness of nonpharmacological interventions in reducing psychological symptoms among patients with chronic low back pain

International Journal of Surgery, 2024 • September 26, 2023

This systematic review and network meta-analysis evaluated the effectiveness of nonpharmacological interventions for reducing psychological symptoms in patients with chronic low back pain (CLBP). The ...

KEY FINDING: Mind body therapy, biopsychosocial approach, and physical therapy were effective in reducing depression compared to the control group.

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Mental HealthNeurology

Henry Head (1861–1940) and his importance for neurology

Der Nervenarzt, 2024 • October 12, 2023

Henry Head's name is primarily associated with Head zones, even though he likely did not create the initial depictions. His groundbreaking work lies in the regeneration of peripheral nerve lesions and...

KEY FINDING: The drawings considered depictions of the Head zones in today’s medical textbooks were actually not created by Head.

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