Medical Imaging Research

KEY FINDING: MEMRI ratios were significantly lower in transection and hemisection groups compared to controls, indicating reduced neuronal activity in injured spinal cords.

KEY FINDING: In vivo imaging reveals reversible axon damage in clinically relevant models of CNS injury and disease, suggesting axonal rescue as a promising therapeutic strategy.

KEY FINDING: The RESOLVE sequence significantly increased the resolution of the diffusion images and improved the median signal-to-noise ratio of the middle (C4–6) and lower (C7–T1) cervical segments to the level of the upper cervical segment.

KEY FINDING: AxonTracer correlates strongly with semi-manual quantification by NeuronJ, a widely used ImageJ plugin, but with full automation and reduced user input.

KEY FINDING: Increased radiation dose (D90) correlated with aggravated pathological damage of neurons and microvessels in the gray matter and white matter.

KEY FINDING: Lower TNF-α expression before surgery was associated with a positive response to non-union therapy.

KEY FINDING: P2RY12 expression increases in murine and human microglia following exposure to anti-inflammatory stimuli.

KEY FINDING: The system effectively characterizes spinal cord damage with 97% accuracy by tracking limb movements and extracting kinematic features.

KEY FINDING: The total rate of all adverse events was 0.13%, and the rate of severe adverse events was 0.04%.

KEY FINDING: SCs and OECs efficiently internalize dextran-coated SPIO from the culture medium by fluid phase pinocytosis.