Browse the latest research summaries in the field of medical imaging for spinal cord injury patients and caregivers.
Showing 211-220 of 231 results
Genome Biology, 2024 • March 8, 2024
SpaDo is introduced as a computational framework for multi-slice spatial domain analysis, including multi-slice spatial domain detection, reference-based spatial domain annotation, and multi-slice clu...
KEY FINDING: SpaDo demonstrates good interpretability, robustness, and tolerance to noise and batch effects in spatial transcriptomic data analysis.
Journal of Biomedical Optics, 2024 • March 19, 2024
This paper introduces the photoacoustic differential attenuation spectrum (PA-DAS) method to study the attenuation characteristics of cancellous bone for osteoporosis diagnosis. The method modifies Bi...
KEY FINDING: The photoacoustic differential attenuation spectrum (PA-DAS) method can effectively differentiate osteoporotic bone from healthy bone.
Quant Imaging Med Surg, 2024 • April 10, 2024
The study validated an AI-based MAC algorithm for improving image quality in low-dose CT scans following percutaneous vertebroplasty (PVP). The AI-MAC algorithm demonstrated superior performance compa...
KEY FINDING: AI-MAC demonstrated no significant difference compared to reference images in CT attenuation, image noise, signal-to-noise ratios (SNRs), and contrast-to-noise ratio (CNR).
eNeuro, 2025 • January 1, 2025
This study demonstrates that norepinephrine axons in the adult mouse brain are capable of regrowth following injury induced by the neurotoxin DSP4, challenging the widely held belief that axons in the...
KEY FINDING: Norepinephrine axons in the adult mouse brain can regrow following injury induced by DSP4.
Journal of Craniovertebral Junction and Spine, 2024 • January 15, 2025
The study compared radiographic outcomes and subsidence rates between hyperlordotic and standard lordotic interbody spacers in ACDF patients. Hyperlordotic spacers led to increased cervical lordosis a...
KEY FINDING: Hyperlordotic spacers resulted in a significantly higher cervical lordosis (CL) at 1-year post-surgery compared to standard lordotic spacers.
Neural Regen Res, 2015 • March 1, 2015
The study investigates the use of magnetic guidance to enhance the delivery of bone marrow mesenchymal stem cells (BMSCs) to spinal cord injury (SCI) sites in rats. Superparamagnetic iron oxide (SPIO)...
KEY FINDING: Superparamagnetic iron oxide nanoparticles effectively label bone marrow mesenchymal stem cells and impart sufficient magnetism to respond to external magnetic fields.
Neural Regeneration Research, 2015 • March 1, 2015
This study aimed to explore the fractional anisotropy and apparent diffusion coefficient of diffusion tensor magnetic resonance imaging and the feasibility of diffusion tensor tractography in the eval...
KEY FINDING: The fractional anisotropy scores after spinal cord transection in rats were significantly lower than those in normal rats (P < 0.05); the apparent diffusion coefficient was significantly increased compared with the normal group (P < 0.05).
eNeuro, 2015 • March 26, 2015
The study introduces optimized methods for visualizing traced axons in cleared spinal cords from transgenic and nontransgenic animals, comparing different AAV serotypes, promoters, and fluorescent pro...
KEY FINDING: AAV8 serotype with UbC promoter expressing GFP provides the strongest fluorescence signal after tetrahydrofuran-based tissue clearing, referred to as 3D imaging of solvent-cleared organs (3DISCO).
Neural Regeneration Research, 2015 • November 1, 2015
The study assessed the potential of diffusion tensor imaging (DTI) for quantitative assessment of compressed lumbosacral spinal nerve roots in patients with lumbosacral stenosis. DTI findings demonstr...
KEY FINDING: DTI showed thinning and distortion in 36 lumbosacral spinal nerve roots (49%) and abruption in 17 lumbosacral spinal nerve roots (23%) in patients with spinal stenosis.
J Neurosci Methods, 2016 • September 15, 2016
The study introduces retroDISCO, a novel optical clearing technique for intact mouse spinal cords, enabling efficient and accurate quantification of retrograde labeled motor neurons using confocal mic...
KEY FINDING: Complete optical clearing of spinal cords using retroDISCO takes approximately four hours. Confocal microscopy can then obtain z-stacks of labeled motor neuron pools within 3–5 minutes.