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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Immunology Research

Browse the latest research summaries in the field of immunology for spinal cord injury patients and caregivers.

Showing 251-260 of 730 results

Spinal Cord InjuryImmunologyHealthcare

Identifying Patterns of Primary Care Antibiotic Prescribing for a Spinal Cord Injury (SCI) Cohort Using an Electronic Medical Records (EMR) Database

Top Spinal Cord Inj Rehabil, 2023 • January 1, 2023

This study investigated primary care antibiotic prescribing patterns for adults with SCI using linked health administrative and electronic medical records databases from 2013 to 2015. The study found ...

KEY FINDING: UTIs were the most common indication for antibiotic prescription, accounting for 59.8% of prescriptions.

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ImmunologyNeurologyRehabilitation

Spinal cord infarction attributed to SARS-CoV-2, with post-acute sequelae of COVID-19: A case report

World Journal of Clinical Cases, 2023 • December 26, 2023

This case report describes a 70-year-old female who developed a spinal cord infarction attributed to acute SARS-CoV-2 infection, resulting in paraplegia and subsequent post-acute sequelae of COVID-19 ...

KEY FINDING: Spinal cord infarction can occur as a rare complication following acute SARS-CoV-2 infection, leading to significant neurological disability.

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Spinal Cord InjuryImmunologyHealthcare

Antibiogram data of urinary tract infection in spinal cord injury patients in an outpatient setting

Neurosciences, 2024 • January 1, 2024

This study analyzed urine culture results from 151 SCI patients with UTIs to determine common causative organisms and their antibiotic sensitivities based on different voiding methods. The most common...

KEY FINDING: E. coli was found to be the most common cause of UTIs overall, especially in patients using self-intermittent catheterization (SIC) and indwelling catheters (IDC).

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Spinal Cord InjuryImmunologyHealthcare

Identifying prescribers of antibiotics in a primary care spinal cord injury cohort

Spinal Cord Series and Cases, 2024 • January 22, 2024

This retrospective cross-sectional study identified that individuals with SCI received outpatient antibiotic prescriptions from multiple sources, with rostered primary care practice physicians being t...

KEY FINDING: Rostered-primary care practice physicians prescribed the majority (58.9%) of dispensed antibiotics to the SCI cohort.

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Spinal Cord InjuryImmunologyRehabilitation

Incidence and risk factors of urinary tract infection in hospitalized patients with spinal cord injury in a hospital of China

Scientific Reports, 2024 • February 10, 2024

This retrospective study analyzed data from 538 hospitalized patients with SCI in China between 2014 and 2023 to determine the incidence and risk factors for urinary tract infections (UTIs). The study...

KEY FINDING: The incidence of UTI in hospitalized patients with SCI in China was found to be 49.8%.

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Spinal Cord InjuryImmunologyPain Management

Impact of inflammation and Treg cell regulation on neuropathic pain in spinal cord injury: mechanisms and therapeutic prospects

Frontiers in Immunology, 2024 • January 29, 2024

This review comprehensively describes the mechanisms underlying the inflammatory response and Treg cell regulation subsequent to spinal cord injury, with a specific focus on exploring the potential mech...

KEY FINDING: Inflammation following spinal cord injury involves the release of mediators like cytokines and chemokines, which stimulate sensory neurons and increase neuronal excitability, leading to pain perception.

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Spinal Cord InjuryImmunologyGastroenterology

Faecal microbiota transplantation for multidrug-resistant organism decolonization in spinal cord injury patients: a case series

Infection Prevention in Practice, 2024 • January 27, 2024

This case series investigates the use of faecal microbiota transplantation (FMT) for decolonizing multidrug-resistant (MDR) bacteria in seven spinal cord injury (SCI) patients. The study found that FM...

KEY FINDING: FMT was successful in decolonizing MDR bacteria in five out of seven spinal cord injury patients.

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Spinal Cord InjuryImmunologyNeurology

Nicotinamide Riboside Regulates Chemotaxis to Decrease Inflammation and Ameliorate Functional Recovery Following Spinal Cord Injury in Mice

Curr. Issues Mol. Biol., 2024 • February 1, 2024

This study investigates the effects of nicotinamide riboside (NR) supplementation on spinal cord injury (SCI) in mice. The findings indicate that NR can effectively increase NAD+ levels in spinal cord...

KEY FINDING: NR supplementation significantly elevated NAD+ levels in the spinal cord tissue of mice after SCI, reversing the decrease typically observed after such injuries.

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Spinal Cord InjuryImmunologySurgery

Diagnostic and Management Challenges of Esophageal Rupture with Concomitant Cervical Abscess in Chronic High Cervical Tetraplegia

Diagnostics, 2024 • February 11, 2024

This case report describes a 65-year-old patient with chronic high cervical tetraplegia who developed an esophageal rupture with a concomitant cervical abscess following previous cervical surgery. The...

KEY FINDING: Esophageal rupture can occur as a rare complication following cervical surgery, even in chronic cases.

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ImmunologyNeurologyRehabilitation

Treatment and Rehabilitation of a Patient with Neuromyelitis Optica Spectrum Disorder-Induced Complete Spinal Cord Injury Following COVID-19 Vaccination: A Case Report

J. Clin. Med., 2024 • February 19, 2024

This case report describes a 52-year-old female who developed NMOSD-induced complete spinal cord injury after receiving the Pfizer–BioNTech COVID-19 vaccine. The patient presented with pain in both ey...

KEY FINDING: The patient experienced a remarkable neurological recovery, transitioning from complete spinal cord injury (AIS-A) to functional independence (AIS-E) after intensive treatment and rehabilitation.

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