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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Brain Injury Research

Browse the latest research summaries in the field of brain injury for spinal cord injury patients and caregivers.

Showing 91-100 of 128 results

Spinal Cord InjuryBioinformaticsBrain Injury

Elucidation of Gene Expression Patterns in the Brain after Spinal Cord Injury

Cell Transplantation, 2017 • July 1, 2017

This study investigates gene expression patterns in the brain after spinal cord injury (SCI) in mice, focusing on acute (3 hours) and subacute (2 weeks) phases post-injury. Transcriptome analysis reve...

KEY FINDING: At the acute phase after SCI, the oxidative phosphorylation pathway in the brain is affected, indicating impaired energy production.

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NeurologyRehabilitationBrain Injury

Rehabilitation modality and onset differentially influence whisker sensory hypersensitivity after diffuse traumatic brain injury in the rat

Restor Neurol Neurosci, 2017 • January 1, 2017

The study determined that the modality and onset of rehabilitation differentially influenced sensory hypersensitivity and plasma CORT levels in sham and diffuse brain-injured rats. Deprivation during ...

KEY FINDING: Deprivation therapy during week two elicited significantly greater sensory hypersensitivity compared to week one.

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Sleep MedicineNeurologyBrain Injury

Repetitive Brain Injury of Juvenile Mice Impairs Environmental Enrichment-Induced Modulation of REM Sleep in Adulthood

Neuroscience, 2018 • April 1, 2018

The study aimed to determine if multiple mild traumatic brain injuries in juvenile mice lead to disrupted sleep cycles in adulthood, and if this effect is prevented by an enriched environment (EE). Th...

KEY FINDING: Repeated mild TBIs in juvenile mice did not significantly alter basal or homeostatic sleep responses in adulthood under standard laboratory conditions.

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Spinal Cord InjuryNeuroimagingBrain Injury

Injury of the Papez circuit in a patient with traumatic spinal cord injury and concomitant mild traumatic brain injury

Neural Regeneration Research, 2018 • January 1, 2018

This study reports on a male patient with memory impairment who showed injury of the Papez circuit following TSCI and concomitant mild TBI. DTT revealed injury of the left thalamocortical tract and th...

KEY FINDING: The patient with TSCI and mild TBI showed memory impairment.

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Mental HealthRehabilitationBrain Injury

Psychological well-being in individuals living in the community with traumatic brain injury

Brain Inj., 2018 • January 1, 2018

The study focused on unemployed individuals with TBI living in the community who expressed interest in improving their psychological well-being. The research found that this group experienced cognitiv...

KEY FINDING: Participants with TBI showed significant cognitive impairment and high levels of emotional distress.

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Spinal Cord InjuryRehabilitationBrain Injury

Functional outcomes in patients with co-occurring traumatic brain injury and spinal cord injury from an inpatient rehabilitation facility’s perspective

The Journal of Spinal Cord Medicine, 2018 • January 1, 2018

This retrospective study examined the occurrence and severity of co-occurring traumatic brain injury (TBI) in persons with traumatic spinal cord injury (SCI) and described differences in functional ou...

KEY FINDING: Forty-one percent of persons with traumatic SCI experienced co-occurring TBI.

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NeurologyGeneticsBrain Injury

Depression following a traumatic brain injury: uncovering cytokine dysregulation as a pathogenic mechanism

Neural Regeneration Research, 2018 • October 1, 2018

Depression is a significant long-term complication of traumatic brain injury (TBI) that can impair cognitive function and overall quality of life. The underlying cause of this increased depression ris...

KEY FINDING: TBI-induced inflammation, characterized by elevated cytokines, is a potential mechanism for post-TBI depression.

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HealthcareBrain Injury

Identification of hidden health utilization services and costs in adults awaiting tertiary care following mild traumatic brain injury in Toronto, Ontario, Canada

Concussion, 2016 • August 8, 2016

This study investigated healthcare utilization and costs for mTBI patients awaiting tertiary care, revealing a significant number of healthcare provider visits during the wait period. The study found ...

KEY FINDING: Males reported an average of 37 healthcare provider visits, while females reported 30, costing over $500,000 Canadian dollars for potentially excess care in one year.

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NeurologyPain ManagementBrain Injury

Headache due to spinothalamic tract injury in patients with mild traumatic brain injury: Two case reports

Medicine, 2019 • February 1, 2019

This study reports two cases of patients with mild TBI who developed headaches due to injury of the spinothalamic tract (STT). Diffusion tensor tractography (DTT) revealed narrowing or discontinuation...

KEY FINDING: DTT scans revealed narrowing of the spinothalamic tract (STT) in both hemispheres of both patients.

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Spinal Cord InjuryPatient ExperienceBrain Injury

Interviewer- vs. Self-administration of PROMIS Measures for Adults with Traumatic Injury

Health Psychol, 2019 • May 1, 2019

This study evaluated mode-of-administration effects in a sample of participants with SCI or TBI for whom interviewer-administered measures may be an especially important option. Adults with SCI or TBI...

KEY FINDING: PROMIS instruments demonstrated measurement equivalence across interviewer- administered and self-administered conditions.

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