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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Brain Injury Research

Browse the latest research summaries in the field of brain injury for spinal cord injury patients and caregivers.

Showing 101-110 of 128 results

NeurologyRehabilitationBrain Injury

Bilateral movement training promotes axonal remodeling of the corticospinal tract and recovery of motor function following traumatic brain injury in mice

Cell Death and Disease, 2013 • March 7, 2013

This study compared the effects of unilateral repetitive and bilateral movement training on motor function recovery in a mouse model of TBI, focusing on corticospinal tract (CST) rewiring. The results...

KEY FINDING: Bilateral movement training (rotarod) enhances motor function recovery more effectively than simple repetitive training (reaching) after TBI in mice.

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Spinal Cord InjuryNeurorehabilitationBrain Injury

Combined SCI and TBI: Recovery of forelimb function after unilateral cervical spinal cord injury (SCI) is retarded by contralateral traumatic brain injury (TBI), and ipsilateral TBI balances the effects of SCI on paw placement

Exp Neurol, 2013 • October 1, 2013

This study investigates the effects of combined spinal cord injury (SCI) and traumatic brain injury (TBI) on forelimb function in rats, using a unilateral cervical contusion and controlled cortical im...

KEY FINDING: SCI combined with contralateral TBI severely impaired paw placement recovery, while SCI with ipsilateral TBI increased paw use on the injured side.

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Spinal Cord InjuryRehabilitationBrain Injury

Effect of rehabilitation length of stay on outcomes in individuals with traumatic brain injury or spinal cord injury: a systematic review protocol

Systematic Reviews, 2013 • July 20, 2013

This systematic review protocol outlines a plan to examine the impact of rehabilitation length of stay on outcomes for individuals with traumatic brain injury (TBI) or spinal cord injury (SCI). The re...

KEY FINDING: The systematic review aims to identify the effect of rehabilitation length of stay and intensity on functional independence and social participation outcomes in individuals with TBI or SCI.

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Spinal Cord InjuryMental HealthBrain Injury

The Impact of Mild Traumatic Brain Injury on Cognitive Functioning Following Co-occurring Spinal Cord Injury

Archives of Clinical Neuropsychology, 2013 • September 20, 2013

This study examined the impact of MTBI on cognitive function in individuals with SCI. Participants were tested between 26 and 76 days post-injury. The study found no significant difference in neuropsy...

KEY FINDING: Persons who sustained traumatic SCI and co-occurring MTBI did not evidence significantly greater impairment on neuropsychological tests when compared with persons who sustained a traumatic SCI alone.

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PediatricsRehabilitationBrain Injury

Residual Cognitive Disability after Completion of Inpatient Rehabilitation among Injured Children

J Pediatr, 2014 • January 1, 2014

The study aimed to determine the prevalence and nature of residual cognitive disability after inpatient rehabilitation for children aged 7-18 years with traumatic injuries. The study found that childr...

KEY FINDING: Children with TBI had more severe cognitive disability on admission to inpatient rehabilitation compared to those with spinal cord injury or other injuries.

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Sleep MedicineNeurologyBrain Injury

Diffuse Brain Injury Induces Acute Post-Traumatic Sleep

PLoS ONE, 2013 • December 26, 2013

This study investigates acute post-traumatic sleep in mice following diffuse traumatic brain injury (TBI) using a non-invasive sleep monitoring system. The results show a significant increase in sleep...

KEY FINDING: Diffuse TBI in mice leads to a significant increase in sleep during the first 6 hours post-injury.

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Regenerative MedicineNeurologyBrain Injury

SCF + G‑CSF treatment in the chronic phase of severe TBI enhances axonal sprouting in the spinal cord and synaptic pruning in the hippocampus

Acta Neuropathologica Communications, 2021 • May 21, 2021

This study investigates the neurorestorative efficacy of repeated SCF + G-CSF treatment in the chronic phase of severe TBI, demonstrating its superiority over single treatments. The treatment enhances...

KEY FINDING: Repeated SCF + G-CSF treatments in the chronic phase of severe TBI lead to better neurological function improvement than single SCF + G-CSF treatment.

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Spinal Cord InjuryRegenerative MedicineBrain Injury

Future Perspectives in Spinal Cord Repair: Brain as Saviour? TSCI with Concurrent TBI: Pathophysiological Interaction and Impact on MSC Treatment

Cells, 2021 • October 30, 2021

This review provides a detailed overview of the local and systemic alterations due to TSCI and TBI, which severely affect multiple physiological systems. It raises awareness of the impact of TSCI–TBI ...

KEY FINDING: TSCI and TBI interact bidirectionally, impacting cognitive and sensorimotor outcomes.

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Critical CareBrain Injury

Perceived Utility of Intracranial Pressure Monitoring in Traumatic Brain Injury: A Seattle International Brain Injury Consensus Conference Consensus-Based Analysis and Recommendations

Neurosurgery, 2023 • August 1, 2023

This study investigated the perceived utility of intracranial pressure (ICP) monitoring among experienced neurotraumatologists. The study used a consensus-based approach, polling members of the Seattl...

KEY FINDING: ICP monitor use is wider than predicted by guidelines.

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NeurologyBrain Injury

The vascular locked-in and locked-in-plus syndrome: A retrospective case series

Therapeutic Advances in Neurological Disorders, 2023 • September 25, 2023

This retrospective case series explored the structural differences between LiS and LiPS patients of vascular etiology, focusing on lesion patterns and locations. The study included nine patients diagn...

KEY FINDING: Lesions in LiS patients are typically round and confined to the pons, the part of the brainstem responsible for motor control.

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