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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Biomedical Research

Browse the latest research summaries in the field of biomedical for spinal cord injury patients and caregivers.

Showing 351-360 of 904 results

NeurologyBioinformaticsBiomedical

Training an Actor-Critic Reinforcement Learning Controller for Arm Movement Using Human-Generated Rewards

IEEE Trans Neural Syst Rehabil Eng, 2017 • October 1, 2017

This study investigates the use of human-generated rewards to train reinforcement learning (RL) controllers for functional electrical stimulation (FES) of arm movements in individuals with spinal cord...

KEY FINDING: RL controllers trained with human and pseudo-human rewards significantly outperformed standard controllers in reaching tasks.

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RehabilitationBiomedicalBiomechanics

Comparing joint kinematics and center of mass acceleration as feedback for control of standing balance by functional neuromuscular stimulation

Journal of NeuroEngineering and Rehabilitation, 2012 • May 6, 2012

This study compared the effectiveness of joint kinematics and center of mass (COM) acceleration feedback for controlling standing balance using functional neuromuscular stimulation (FNS) in individual...

KEY FINDING: Compared to constant stimulation, feedback control systems using joint kinematics, COM acceleration, or a combination reduced the need for upper extremity support by 51%, 43%, and 56%, respectively.

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Spinal Cord InjuryNeurologyBiomedical

A muscle-driven approach to restore stepping with an exoskeleton for individuals with paraplegia

Journal of NeuroEngineering and Rehabilitation, 2017 • May 16, 2017

The study presents a self-contained muscle-driven exoskeleton to restore stepping in individuals with paraplegia due to SCI. The untethered hybrid system coordinates exoskeletal constraints with muscl...

KEY FINDING: The hybrid neuroprosthesis (HNP) system restored stepping in three individuals with motor complete paralysis due to SCI.

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Spinal Cord InjuryNeurologyBiomedical

Reactive stepping with functional neuromuscular stimulation in response to forward-directed perturbations

Journal of NeuroEngineering and Rehabilitation, 2017 • June 1, 2017

This study presents a reactive stepping controller designed for individuals with spinal cord injuries using implanted neuroprostheses. The controller utilizes body-mounted accelerometers to detect for...

KEY FINDING: The controller effectively initiated steps for all perturbations with magnitude between 10 and 17.5 s body weight, and initiated a postural response with occasional steps at 5% body weight.

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Spinal Cord InjuryUrologyBiomedical

Intraspinal stimulation for bladder voiding in cats before and after chronic spinal cord injury

J Neural Eng, 2007 • December 1, 2007

This study evaluated the effects of intraspinal microstimulation on bladder voiding in cats before and after spinal cord injury. Microelectrode arrays were implanted in the sacral spinal cord to stimu...

KEY FINDING: Stimulation at the S1 level produced strong bladder contractions and EUS relaxation, resulting in voiding in 14 animals.

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NeurologyBiomedical

Emulation of computer mouse control with a noninvasive brain-computer interface

J Neural Eng, 2008 • June 1, 2008

This study demonstrates that a noninvasive BCI using EEG can provide people with multidimensional movement and selection capabilities, emulating mouse operation. The results show that users can learn ...

KEY FINDING: People can learn to use scalp-recorded EEG rhythms to move a cursor in two dimensions to reach a target and then to select the target.

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Spinal Cord InjuryNeurologyBiomedical

Hindlimb Movement in the Cat Induced by Amplitude-Modulated Stimulation Using Extra-Spinal Electrodes

J Neural Eng, 2008 • June 1, 2008

The study demonstrated that extra-spinal electrical stimulation, particularly when amplitude-modulated, can induce coordinated hindlimb movements in cats, including flexion, extension, and stepping. T...

KEY FINDING: Stimulation location influences movement type: rostral segments (L5) induced flexion, caudal segments (L7/S1) induced extension.

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NeurologyBiomedical

Automated optimal coordination of multiple-degree-of-freedom neuromuscular actions in feedforward neuroprostheses

IEEE Trans Biomed Eng, 2009 • January 1, 2009

This paper describes a new method for designing feedforward controllers for multiple-muscle, multiple-degree-of-freedom, motor system neural prostheses. We tested the method experimentally in ten able...

KEY FINDING: Good control of isometric force was achieved in both degrees of freedom, with RMS errors less than 10% of the force range in seven experiments.

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Biomedical

Adaptive Control of Movement for Neuromuscular Stimulation-Assisted Therapy in a Rodent Model

IEEE Trans Biomed Eng, 2009 • February 1, 2009

This study implemented an adaptive control system in a rodent model for neuromotor therapy to address the shortcomings of previous open-loop control systems, which were unable to generate accurate mov...

KEY FINDING: The adaptive PG/PS control system provided excellent movement tracking with less than 10% error in 100-cycle movement trials, although stimulation levels increased to counteract muscle fatigue.

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BioinformaticsBiomedical

Combined feedforward and feedback control of a redundant, nonlinear, dynamic musculoskeletal system

Med Biol Eng Comput, 2009 • May 1, 2009

This paper introduces a feedforward–feedback controller for a two-joint, six-muscle arm model, designed for functional electrical stimulation (FES) systems. The controller incorporates an artificial n...

KEY FINDING: The combined feedforward-feedback controller achieved a tracking error of less than 4° in ideal conditions.

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