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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Alternative Medicine Research

Browse the latest research summaries in the field of alternative medicine for spinal cord injury patients and caregivers.

Showing 61-70 of 188 results

Spinal Cord InjuryAlternative MedicineNeurology

Iridoids rich fraction from Valeriana jatamansi Jones promotes axonal regeneration and motor functional recovery after spinal cord injury through activation of the PI3K/Akt signaling pathway

Frontiers in Molecular Neuroscience, 2024 • May 2, 2024

This study investigates the therapeutic effect of Iridoid-rich fraction derived from Valeriana jatamansi Jones (IRFV) on spinal cord injury (SCI) and its underlying mechanism, focusing on axonal regen...

KEY FINDING: IRFV significantly enhanced motor function recovery, reduced pathological injury, and facilitated axonal regeneration in SCI rats.

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Spinal Cord InjuryAlternative MedicineImmunology

Phillygenin inhibits neuroinflammation and promotes functional recovery after spinal cord injury via TLR4 inhibition of the NF-κB signaling pathway

Journal of Orthopaedic Translation, 2024 • July 29, 2024

We found that PHI exerted anti- neuroinflammatory effects by inactivating the NF-κB signaling pathway by targeting TLR4. PHI can efficiently prevent microglial activation and the subsequent neuroinfla...

KEY FINDING: PHI significantly inhibited the inflammatory response and neuronal apoptosis while enhancing axonal regeneration and improving motor function recovery in vivo.

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Alternative MedicineNeurology

Acupuncture promotes neurological recovery and regulates lymphatic function after acute inflammatory nerve root injury

Heliyon, 2024 • August 6, 2024

The study aimed to investigate the therapeutic effect of acupuncture on acute inflammatory nerve root injury by regulating lymphatic function, using a mouse model of L5 nerve root compression. Key fin...

KEY FINDING: Acupuncture increased the mechanical pain threshold in mice with nerve root injury, suggesting a pain-relieving effect.

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Cardiovascular ScienceAlternative MedicinePain Management

Electroacupuncture Relieves Neuropathic Pain via Adenosine 3 Receptor Activation in the Spinal Cord Dorsal Horn of Mice

Int. J. Mol. Sci., 2024 • September 24, 2024

The study investigates the efficacy of electroacupuncture (EA) in mitigating neuropathic pain (NPP) in mice by examining the role of adenosine A3 receptors (Adora-3) in the central nervous system. EA ...

KEY FINDING: EA upregulates Adora-3 and CD73 expression while inhibiting ADA expression in the spinal cord dorsal horn (SCDH) of mice with spared nerve injury (SNI)-induced neuropathic pain.

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Alternative MedicineNeurologyRehabilitation

Efficacy of combined electroacupuncture and moxibustion for treatment of neurogenic bladder after spinal cord injury: A retrospective analysis

Medicine, 2024 • December 1, 2024

This retrospective study evaluated the clinical efficacy of combined electroacupuncture and moxibustion for the treatment of neurogenic bladder in patients with spinal cord injury. The study found tha...

KEY FINDING: The study group (electroacupuncture combined with moxibustion) showed significantly greater improvement in bladder function compared to the control group (electroacupuncture alone).

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Alternative MedicineImmunologyPain Management

Analgesic effect of Dahuang Fuzi Decoction in neuropathic pain through inhibiting TNF-α and PI3K-AKT signaling

Front. Neurosci., 2024 • December 11, 2024

This study investigates the analgesic effects of Dahuang Fuzi Decoction (DF) on neuropathic pain (NeP) using a rat model of chronic sciatic nerve compression injury (CCI). The research combines chemic...

KEY FINDING: DF treatment significantly increased the mechanical withdrawal threshold (MWT) and thermal withdrawal latency (TWL) in CCI rats, indicating its analgesic effect.

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Spinal Cord InjuryAlternative MedicineRehabilitation

Efficacy analysis of acupuncture and rehabilitation for traumatic spinal cord injury

Medicine, 2025 • January 1, 2025

This study investigates the role and efficacy of acupuncture combined with rehabilitation therapy during the recovery phase of patients with traumatic spinal cord injury. Posttreatment assessments rev...

KEY FINDING: Acupuncture combined with rehabilitation therapy led to significant improvements in residual urine volume and detrusor pressure compared to rehabilitation therapy alone.

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Alternative MedicineNeurologyResearch Methodology & Design

Sciatic nerve injury treated by acupuncture: a bibliometric study and visualization analysis

Frontiers in Neurology, 2024 • December 31, 2024

This study uses visualization software VOSviewer and CiteSpace to provide the current status and trends in SNI of acupuncture over the past decade and predicts potential research frontiers and hot dir...

KEY FINDING: Acupuncture combined with drug therapy, physical therapy, and rehabilitation training can comprehensively improve the treatment effect for sciatic nerve injury.

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Spinal Cord InjuryAlternative MedicineNeurology

Electroacupuncture Improves the Motor Function in Rats with Spinal Cord Injury by Regulating UCN2‑Mediated cAMP‑PKA Signaling in the Spinal Cord Microenvironment

Cellular and Molecular Neurobiology, 2025 • February 11, 2025

This study investigated the effects of electroacupuncture (EA) on spinal cord injury (SCI) in rats, focusing on the role of urocortin 2 (UCN2) and the cAMP-PKA signaling pathway. EA treatment improved...

KEY FINDING: EA treatment significantly improved behavioral scores and hind-limb locomotion in rats with SCI at 7, 14, and 28 days post-injury.

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Spinal Cord InjuryAlternative Medicine

Acupuncture combined with moxibustion promote the recovery of spinal cord injury in correlation with Shh/Gli-1 signaling pathway

The Journal of Spinal Cord Medicine, 2022 • January 1, 2022

This study aimed to determine the effect and mechanism of acupuncture combined with moxibustion (AM) treatment on spinal cord injury (SCI) recovery in rats. The results demonstrated that AM treatment ...

KEY FINDING: Acupuncture combined with moxibustion (AM) treatment significantly improved hindlimb motor function in SCI rats compared to the SCI group.

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