Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 4,011-4,020 of 12,052 results
Frontiers in Neurology, 2022 • September 15, 2022
This study conducted quantitative and qualitative analyses on 213 publications in the field of acupuncture for SCI in the WOS core database from 1979 to 2021. Quantitative analysis shows a fluctuating...
KEY FINDING: The number of publications related to acupuncture for SCI showed a fluctuating upward trend from 1979 to 2021.
The Journal of Immunology, 2022 • September 15, 2022
The study explores the transcriptomic profile of CD8+ T cells in the brains of aged and Alzheimer's disease (AD) transgenic mice, comparing them to CD8+ T cells in the blood and identifying them as ti...
KEY FINDING: Brain CD8+ T cells in both AD transgenic and aged wild-type mice exhibit a gene signature characteristic of tissue-resident memory (Trm) T cells.
The Journal of Neuroscience, 2022 • September 14, 2022
The study investigates the role of adult-born dentate granule cells (DGCs) in feedback inhibition and recurrent excitation in the dentate gyrus following traumatic brain injury (TBI) using a controlle...
KEY FINDING: Activation of DGCs born before CCI increased feedback inhibition in mature DGCs and excitation in parvalbumin-expressing basket cells (PVBCs) compared to sham controls.
Interact CardioVasc Thorac Surg, 2022 • September 14, 2022
This study evaluated the outcomes of descending thoracic aortic repair (DTAR) for chronic aortic dissection (CAD) at a single center, finding good early and long-term results. The study identified age...
KEY FINDING: Descending thoracic aortic repair for chronic aortic dissection resulted in good early and long-term results.
Journal of Extracellular Biology, 2022 • September 14, 2022
The “massivEVs” workshop focused on the challenges and potential solutions for large-scale EV production, bringing together experts from academia and industry. Key areas discussed included manufacturi...
KEY FINDING: EV purity may not always correlate with functionality, and co-isolates could contribute to function and stability.
Br J Nutr, 2022 • September 14, 2022
This review highlights the importance of considering the unique metabolic and physiological changes that occur after SCI when developing nutritional recommendations. The authors emphasize the need for...
KEY FINDING: Individuals with SCI often have an increased risk of neurogenic obesity, which results from dysfunction of energy metabolism, physical deconditioning, and altered hormonal homeostasis.
BMC Neurology, 2022 • September 14, 2022
This case report describes a rare instance of long-segment spinal cord infarction complicated by multiple cerebral infarctions in a 65-year-old male. The patient presented with sudden pain, weakness, ...
KEY FINDING: Long-segment spinal cord infarction can occur in conjunction with multiple cerebral infarctions, presenting a complex clinical picture.
Int. J. Environ. Res. Public Health, 2022 • September 14, 2022
This study evaluated gait initiation in iSCI patients using wearable IMUs in dry land and water immersion conditions. The aquatic condition showed an increased first step duration and decreased RMS acc...
KEY FINDING: In the aquatic environment, the initial step lasted longer compared to walking on land.
Neurochemical Research, 2022 • September 14, 2022
This study investigates the effects of the ROCK inhibitor Y27632 on astrocytes and functional recovery in a rat model of SCI. The findings demonstrate that Y27632 promotes functional recovery after SC...
KEY FINDING: Y27632 treatment improved functional recovery of SCI and elevated the proliferation and migration abilities of the astrocytes.
Sci. Adv., 2022 • September 14, 2022
This study demonstrates that Chk2 is a promising therapeutic target for preventing functional decline in both acute and chronic neurological diseases. Targeting Chk2 suppresses neurodegeneration in Dr...
KEY FINDING: Knockdown of ATM and Chk2 is neuroprotective in Drosophila models of chronic neurodegeneration, suggesting that suppressing the ATM-Chk2 pathway can help preserve neuronal function.