Browse the latest research summaries in the field of rheumatology for spinal cord injury patients and caregivers.
Showing 11-16 of 16 results
Front. Rehabil. Sci., 2025 • March 14, 2025
This case series describes the presentation, diagnostic evaluation, treatment, and functional outcomes of two adolescent female patients diagnosed with lupus myelitis as a first manifestation of new-on...
KEY FINDING: Early aggressive immunomodulatory treatment (IMT) and intensive inpatient rehabilitation led to significant laboratory and functional improvement in both patients.
J Med Case Reports, 2021 • May 10, 2021
This case report describes a 70-year-old man with ankylosing spondylitis who presented with severe intercostal neuralgia, initially misdiagnosed as herpes zoster. Further investigation revealed an atr...
KEY FINDING: Severe intercostal neuralgia can be an early symptom of atraumatic spinal fractures in patients with ankylosing spondylitis.
Spinal Cord Series and Cases, 2016 • July 7, 2016
This study is a retrospective descriptive survey of post-acute, traumatic AS-SCI patients, transferred from the neurosurgical department and admitted in a Romanian Neurorehabilitation Clinic, during 2...
KEY FINDING: Low-energy trauma was incriminated in 54.5% cases.
Reumatologia, 2017 • April 1, 2017
Cervical spine involvement is common in rheumatoid arthritis (RA) and can lead to various types of instability, potentially causing neurological complications. Early identification of these instabilit...
KEY FINDING: Plain radiographs are a common initial imaging method due to their availability and low cost, particularly for assessing atlanto-axial joint anomalies using functional radiographs in flexion and extension.
Inflammation Research, 2024 • February 11, 2024
This study used Mendelian randomization to investigate the causal effects of lipid-lowering drug targets on psoriatic arthritis (PsA) risk. The analysis revealed a significant association between gene...
KEY FINDING: Genetically proxied PCSK9 inhibition is associated with a decreased risk of psoriatic arthritis (OR: 0.51; 95% CI 0.14–0.88; P < 0.01).
British Journal of Pharmacology, 2018 • January 1, 2018
This study investigates the analgesic effects of ASP3662, a novel 11β-HSD1 inhibitor, in rat models of neuropathic and dysfunctional pain. ASP3662 is a potent, selective, and CNS-penetrable inhibitor ...
KEY FINDING: ASP3662 effectively inhibits 11β-HSD1 in humans, mice, and rats, demonstrating selectivity over 11β-HSD2 and showing no significant impact on other enzymes, transporters, and receptors.