Browse the latest research summaries in the field of research methodology & design for spinal cord injury patients and caregivers.
Showing 571-580 of 702 results
Neurology, 2019 • July 2, 2019
This meta-analysis of 549 preclinical SCI studies including 9,535 animals provides empirical evidence of prevalent bias in the design and reporting of experimental SCI studies, resulting in overestima...
KEY FINDING: Interventions reported a neurobehavioral outcome improvement of 26.3%.
Spinal Cord Series and Cases, 2019 • February 22, 2019
This case report underscores the inadequate care and support systems for individuals with spinal cord injuries (SCI) in India, emphasizing the lack of specialized rehabilitation centers, expertise in ...
KEY FINDING: Mishandling at the accident site and during transportation to the hospital exacerbated the patient's condition due to a lack of awareness among the general public and ambulance staff.
Annals of Rehabilitation Medicine, 2019 • July 1, 2019
This study investigated the potential of miRNA-21 and miRNA-223 as indicators of the severity and acute phase of spinal cord injury (SCI) using a balloon-compression model in rats. The results showed ...
KEY FINDING: Significant differences in miRNA-21 expression levels were observed between the experimental groups at 1, 3, and 7 days post-injury, suggesting that miRNA-21 expression levels might serve as an indicator of the severity of SCI.
BMC Neurology, 2019 • July 3, 2019
The study investigated physical strategies used by individuals with SCI and their families to overcome physical disability, revealing a main theme of 'towards overcoming physical disability' with thre...
KEY FINDING: Participants used physiotherapy and occupational therapy as essential for rehabilitation. They also invented simple rehabilitation equipment with family help.
Neuromuscul Disord, 2019 • July 1, 2019
This study tracked changes in reachable workspace upwards for 5-years in 18 FSHD subjects. Reachable workspace declined more significantly if the subjects were challenged with 500g wrist weights The s...
KEY FINDING: Reachable workspace declined −1.63%/year in total (p=0.144), with most decline in above-the-shoulder quadrants.
GMS German Medical Science, 2019 • June 17, 2019
This clinical practice guideline provides a structured approach to pain management in individuals with spinal cord injury (SCI), addressing challenges in classification, assessment, and therapy. The g...
KEY FINDING: The guideline recommends the International Spinal Cord Injury Pain (ISCIP) classification for SCI-related pain.
Systematic Reviews, 2019 • August 22, 2019
This systematic review and meta-analysis is designed to assess the independent and combined effects of age at time of injury and elapsed time since injury on quality of life in persons with chronic SC...
KEY FINDING: The primary objective is to establish the effects of participant age and time since injury on QoL scores.
Spinal Cord Series and Cases, 2019 • June 1, 2019
This study describes methodological issues, experienced challenges related to data collection in North Macedonia and to discuss possible improvements of epidemiological data collection in future studi...
KEY FINDING: The study identified three major challenges with data collection in this setting: (1) research logistics and procedures, such as recruitment, infrastructure, and compensation, (2) ethical issues and the initial lack of mutual trust and understanding between researchers and participants, and (3) scientific quality and interpretation, including representativeness.
Neurological Research and Practice, 2019 • April 4, 2019
This study demonstrates a positive correlation between ulnar nerve CMAP amplitudes and AIS incompleteness over time in cervical SCI patients. Early ulnar nerve axonal integrity (within 4 weeks) is an ...
KEY FINDING: Higher ulnar nerve CMAP amplitudes are associated with better AIS grades over the entire follow-up period in cervical SCI patients.
JOURNAL OF NEUROTRAUMA, 2012 • June 10, 2012
The study quantitatively assessed SCI clinical trials against ICCP best practice guidelines and representation of the SCI population. It found increasing trends in randomization, blinding, and use of ...
KEY FINDING: Most interventional studies were randomized and controlled, aligning with ICCP recommendations, and blinding practices have increased over time.