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Research Methodology & Design Research

Browse the latest research summaries in the field of research methodology & design for spinal cord injury patients and caregivers.

Showing 341-350 of 702 results

Spinal Cord InjuryUrologyResearch Methodology & Design

Review Recommendations for evaluation of bladder and bowel function in pre-clinical spinal cord injury research

The Journal of Spinal Cord Medicine, 2020 • January 1, 2020

The goal of this article is to provide guidance for selection of bladder and bowel measures applicable as either primary or ancillary outcomes. Several fundamental assessments share reasonable levels ...

KEY FINDING: Three fundamental measures each for bladder and bowel assessments were identified, centering upon tissue morphology, voiding efficiency/volume, and smooth muscle-mediated pressure studies.

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Spinal Cord InjuryNutrition & DieteticsResearch Methodology & Design

Effect of docosahexaenoic acid on the recovery of motor function in rats with spinal cord injury: a meta-analysis

Neural Regen Res, 2020 • March 1, 2020

This meta-analysis assesses the effect of DHA on motor function recovery in rat models of SCI, confirming that DHA administration significantly improved functional recuperation. The ability of DHA to ...

KEY FINDING: The highest mean Basso, Beattie, and Bresnahan scale score occurred at 42 days after DHA treatment in spinal cord injury rats.

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Alternative MedicineTraumaResearch Methodology & Design

Cervical epidural hematoma after spinal manipulation therapy: a case report

BMC Musculoskeletal Disorders, 2019 • October 9, 2019

This case report presents a rare instance of cervical epidural hematoma and tetraplegia following spinal manipulation therapy in a 55-year-old male with no prior history of related conditions. The pat...

KEY FINDING: A 55-year-old man developed tetraplegia and spinal shock after cervical spinal manipulation for stiff neck pain, with no prior history of coagulation disorders or anticoagulant use.

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Spinal Cord InjuryMental HealthResearch Methodology & Design

Diagnostic accuracy and feasibility of depression screening in spinal cord injury: A systematic review

The Journal of Spinal Cord Medicine, 2019 • January 1, 2019

This systematic review aimed to evaluate the diagnostic accuracy and feasibility of various depression screening tools for adults with spinal cord injury (SCI/D) by comparing them against clinical ass...

KEY FINDING: The Patient Health Questionnaire-9 (PHQ-9) demonstrated the highest sensitivity (100%) and specificity (84%) compared to other screening tools, indicating its accuracy in identifying individuals with and without depression.

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Spinal Cord InjuryRehabilitationResearch Methodology & Design

The graded redefined assessment of strength sensibility and prehension version 2 (GV2): Psychometric properties

The Journal of Spinal Cord Medicine, 2019 • January 1, 2019

This study evaluated the psychometric properties of GRASSP Version 2 (GV2), an updated version of an upper extremity measure designed for individuals with traumatic tetraplegia. The results indicate t...

KEY FINDING: Inter-rater and test-retest reliability for all subtests of GV2 ranged between 0.849–0.971 and 0.950–0.971 respectively, indicating excellent reliability.

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AnesthesiologySpinal DisordersResearch Methodology & Design

Catastrophic thoracolumbar spinal massive hematoma triggered by intraspinal anesthesia puncture

Medicine, 2019 • October 18, 2019

This case report details a catastrophic outcome following intraspinal anesthesia due to an undiagnosed spinal deformity leading to an intradural hematoma. The patient suffered significant neurological...

KEY FINDING: The patient presented with a massive spindle-like intradural hematoma compressing the dural sac, extending from T12 to S2.

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Spinal Cord InjuryHealthcareResearch Methodology & Design

FAIR SCI Ahead: The Evolution of the Open Data Commons for Pre-Clinical Spinal Cord Injury Research

JOURNAL OF NEUROTRAUMA, 2020 • March 15, 2020

The paper summarizes the policy outcomes of the FAIR-SCI Ahead meeting and reports on progress implementing these policies in the form of a digital ecosystem: the Open Data Commons for Spinal Cord Inj...

KEY FINDING: The ODC-SCI implements FAIR data sharing and enables pooled data-driven discovery while crediting the generators of valuable SCI data.

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Spinal Cord InjuryRehabilitationResearch Methodology & Design

Validation and application of the International Classification of Functioning core set for spinal cord injury in the Turkish patients

Turk J Phys Med Rehab, 2019 • January 30, 2019

The study applied the Comprehensive ICF-Core Set for SCI-early post-acute-situation in Turkish SCI patients to evaluate common problems and investigate construct validity. The study found that Turkish...

KEY FINDING: 55 of the 63 ICF categories of the Component Body Functions (CBF) and each and every category for the Component Body Structures (CBS) as well as the Component Activities and Participation (CAP) were reported as a problem among the Turkish patients with SCI.

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Spinal Cord InjuryEducationResearch Methodology & Design

Development of the International Spinal Cord Injury/Dysfunction Education Basic Data Set

Spinal Cord Series and Cases, 2019 • August 11, 2019

The study developed the International SCI/D Education Basic Data Set to standardize the collection of essential information about the educational experiences of children and youth with SCI/D. The data...

KEY FINDING: The International SCI/D Education Basic Data Set Version 1.0 consists of 16 items. These items are categorized into three domains: school setting/therapeutic services, school participation/academic success, and barriers/attitudes.

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Spinal Cord InjuryGeneticsResearch Methodology & Design

Therapeutic effect of regulating autophagy in spinal cord injury: a network meta-analysis of direct and indirect comparisons

Neural Regen Res, 2020 • December 10, 2019

This meta-analysis aimed to evaluate the effects of autophagy regulation on spinal cord injury (SCI) in rats through direct and indirect comparisons of relevant studies. The study found that both upre...

KEY FINDING: Upregulation of autophagy significantly elevated Basso, Beattie, and Bresnahan scores at 1 day, 3 days, 1 week, 2 weeks, 3 weeks and 4 weeks after spinal cord injury compared with the control group.

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